Pentoxifylline protects against loss of function and renal interstitial fibrosis in chronic experimental partial ureteral obstruction.

Tubulointerstitial fibrosis (TIF) is a hallmark of chronic kidney disease resulting from diverse etiologies and predicts severity and progression of the kidney disease. To investigate the pathogenesis of TIF, complete unilateral ureteral obstruction (UUO) is the most widely used animal model. However, UUO precludes evaluation of renal function.

Toward a new definition of 'refugee': is the 1951 convention out of date?

Definitions, by necessity, may change or need to be changed to accommodate situations that arise. The United Nations recognized that the emergence of new refugee situations required changes in the Convention. These changes were codified in the 1967 Protocol Relating to the Status of Refugees.

Efficacy of postoperative continuous wound infiltration with local anesthetic after major abdominal surgery.

The aim of this study was to evaluate the analgesic efficacy, safety, opioid sparing effects and improvement of respiratory function when using 0.2% ropivacaine continuous wound infiltration after major intra-abdominal surgery. Forty patients undergoing major intra-abdominal surgery requiring a midline incision of > or = 20 cm were enrolled into this IRB-approved, randomized, prospective controlled study.

International Disaster Response Law: an introduction.

Objective: To review the current state of International Disaster Response Law (IDRL) and identify barriers to development and future directions.

Design: This study is an introduction to the current status of IDRL.

Conclusions: The data suggest that globally we will have increasing incidents and costs in responding to disasters, but the development of IDRL has not kept pace.