Bidirectional bionic limbs: a perspective bridging technology and physiology.

Precise control of bionic limbs relies on robust decoding of motor commands from nerves or muscles signals and sensory feedback from artificial limbs to the nervous system by interfacing the afferent nerve pathways. Implantable devices for bidirectional communication with bionic limbs have been developed in parallel with research on physiological alterations caused by an amputation. In this perspective article, we question whether increasing our effort on bridging these technologies with a deeper understanding of amputation pathophysiology and human motor control may help to overcome pressing stalls in the next generation of bionic limbs.

Simultaneous decoding of cardiovascular and respiratory functional changes from pig intraneural vagus nerve signals.

. Bioelectronic medicine is opening new perspectives for the treatment of some major chronic diseases through the physical modulation of autonomic nervous system activity. Being the main peripheral route for electrical signals between central nervous system and visceral organs, the vagus nerve (VN) is one of the most promising targets.

Systematic analysis of wavelet denoising methods for neural signal processing.

Among the different approaches for denoising neural signals, wavelet-based methods are widely used due to their ability to reduce in-band noise. All wavelet denoising algorithms have a common structure, but their effectiveness strongly depends on several implementation choices, including the mother wavelet, the decomposition level, the threshold definition, and the way it is applied (i.e.

Soft Embodiment for Engineering Artificial Limbs.

We highlight two alternative, yet complementary, solutions for harnessing available neural resources for improving integration of artificial limbs (ALs) through embodiment. 'Hard' embodiment exploits neural and cognitive body mechanisms by closely mimicking their original biological functions. 'Soft' embodiment exploits these same mechanisms by recycling them to support a different function altogether.