The Reindeer Circadian Clock Is Rhythmic and Temperature-compensated But Shows Evidence of Weak Coupling Between the Secondary and Core Molecular Clock Loops.

Circadian rhythms synchronize the internal physiology of animals allowing them to anticipate daily changes in their environment. Arctic habitats may diminish the selective advantages of circadian rhythmicity by relaxing daily rhythmic environmental constraints, presenting a valuable opportunity to study the evolution of circadian rhythms. In reindeer, circadian control of locomotor activity and melatonin release is weak or absent, and the molecular clockwork is reportedly non-functional.

Bioinformatic identification of monkeypox virus phylogenetic gene trees that are representative of its whole-genome phylogenetic tree.

Phylogenetic analysis based on whole-genome sequences is the gold standard for monkeypox virus (MPXV) phylogeny. However, genomic epidemiology capability and capacity are lacking or limited in resource poor countries of sub-Saharan Africa. Therefore, these make real-time genome surveillance of MPXV virtually impossible.

Scaling the high latitudes: evolution, diversification, and dispersal of Coryphella nudibranchs across the Northern Hemisphere.

Nudibranch molluscs Coryphella are widely distributed and species-rich gastropod group lacking fossil record and displaying a complex distribution across both Southern and Northern hemispheres. In this paper we provide a detailed review of the morphology, ecology, and distribution of Coryphella, estimation of divergence times between species, an ancestral area reconstruction, and a population analysis of widely distributed trans-Arctic species Coryphella verrucosa to investigate the evolution, phylogeographic patterns and reconstruct possible historical routes of oceanic dispersal. The inclusion of a larger sample size and five molecular markers has revealed a complex evolutionary history of Coryphella, shaped by transgression, vicariance, and dietary shifts, and overall driven by the pervasive effect of glacial cycles.

Increasing mind wandering with accelerated intermittent theta burst stimulation over the left dorsolateral prefrontal cortex.

Mind wandering (MW) is the intentional or unintentional experience of attending to internal task-unrelated thoughts while being occupied with an external task. Even though maintaining task focus is assumed to require executive functions (EF), it is not clear how and to what extent MW and EF interact. Research has found that activity in the dorsolateral prefrontal cortex (DLPFC) is associated with EF and MW.

Clinical decision-making during childbirth in health facilities from the perspectives of labouring women, relatives, and health care providers: A scoping review.

Problem: For health care providers to ensure appropriate decision-making in clinical settings during childbirth, facilitators and barriers must be identified.

Background: Women who experience a sense of control by participating in the decision-making process, are more likely to have a positive birth experience. However, decision-making may involve hierarchies of close observation and control.

Seasonal dynamics of chemistry in an Arctic glacier-fed river.

Arctic rivers, intricately linked to fjord systems, wield significant influence over the geochemical and biological dynamics of the upper Arctic Ocean, providing it with freshwater, nutrients, suspended particles, and potentially harmful pollutants. To comprehend the full picture of the Arctic ecosystem, it is crucial to understand how these rivers vary across regions and seasons, especially considering ongoing climate changes. However, comprehensive studies that address long-term observations and seasonal variations in Arctic rivers' geochemical composition remain scarce.

Artificial Intelligence Algorithm for Subclinical Breast Cancer Detection.

Importance: Early breast cancer detection is associated with lower morbidity and mortality.

Objective: To examine whether a commercial artificial intelligence (AI) algorithm for breast cancer detection could estimate the development of future cancer.

Design, Setting, And Participants: This retrospective cohort study of 116 495 women aged 50 to 69 years with no prior history of breast cancer before they underwent at least 3 consecutive biennial screening examinations used scores from an AI algorithm (INSIGHT MMG, version 1.

Dietary plasticity in small Arctic copepods as revealed with prey metabarcoding.

Objectives: Small copepods (<2 mm) compose an important constituent of the Arctic marine food web, but their trophic interactions remain largely unexplored, partly due to methodological limitations.

Methods: We here characterize the prey of the abundant cyclopoid , harpacticoid and calanoid spp. from the Arctic Barents Sea and Nansen Basin during four seasons using brute force prey metabarcoding of the 18S rRNA gene.

Frailty and health-related life quality in long-term follow up of intensive care patients above 65 years old: Protocol for a Norwegian prospective, observational multicenter study.

Background: Frailty is strongly correlated with mortality in intensive care unit patients, yet routine screening among intensive care patients is rarely performed. The aim of this study is to assess frailty and health-related quality of life (HRQoL) in patients before intensive care admission and to compare this with outcomes after 3 and 12-months. The Clinical Frailty Scale and EQ-5D-5L will be used to assess frailty and HRQoL, respectively.

"I Am Forever Changed": A Phenomenological Study of the Existential Experiences of Parents of Children and Young People With Complex Care Needs.

Aim: To explore the existential lived experiences of parents of children and young people with complex care needs.

Design: An explorative qualitative design.

Methods: We conducted 16 in-depth interviews with parents of children and young people with complex care needs across Norway from February to May 2022.

Corrigendum: Vowel perception in multilingual speakers: ERP evidence from Polish, English and Norwegian.

[This corrects the article DOI: 10.3389/fpsyg.2023.

Podoplanin expressing macrophages and their involvement in tertiary lymphoid structures in mouse models of Sjögren's disease.

Tertiary lymphoid structures (TLSs) are formed in tissues targeted by chronic inflammation processes, such as infection and autoimmunity. In Sjögren's disease, the organization of immune cells into TLS is an important part of disease progression. Here, we investigated the dynamics of tissue resident macrophages in the induction and expansion of salivary gland TLS.

Single-cell phenotypic profiling and backtracing exposes and predicts clinically relevant subpopulations in isogenic Staphylococcus aureus communities.

Isogenic bacterial cell populations are phenotypically heterogenous and may include subpopulations of antibiotic tolerant or heteroresistant cells. The reversibility of these phenotypes and lack of biomarkers to differentiate functionally different, but morphologically identical cells is a challenge for research and clinical detection. To overcome this, we present ´Cellular Phenotypic Profiling and backTracing (CPPT)´, a fluorescence-activated cell sorting platform that uses fluorescent probes to visualize and quantify cellular traits and connects this phenotypic profile with a cell´s experimentally determined fate in single cell-derived growth and antibiotic susceptibility analysis.

Return to work in younger patients with brain metastases who survived for 2 years or more.

Purpose: The study's purpose was to analyze return to work and other long-term outcomes in younger patients with newly diagnosed brain metastases, treated before they reached legal retirement age, i.e. younger than 65 years.

Support for Siblings of Children With Complex Care Needs: Public Health Nurses' Perceptions of Their Role in Primary Schools.

Aim: To explore the role of public health nurses (PHNs) in Norwegian primary school health services in supporting siblings who have a brother or a sister with complex care needs.

Design: A qualitative, exploratory design using focus groups combined with visual methods.

Methods: Nineteen Norwegian PHNs participated in three focus group discussions between May and September 2022.

"Sometimes I Get So Extremely Tired": Sámi Healthcare Staff Experiences of Cultural Load in Practice.

The study aim was to explore how Sámi healthcare staff experience working as an ethnic minority in the Norwegian healthcare system. This was a qualitative focus group and individual interview study inspired by interpretive description, with 14 participants. The results indicate that Sámi healthcare staff experience various degrees of cultural load in their jobs.

Discovering the true nature of chronic pelvic pain: Are we asking the right questions?

Chronic pelvic pain is a debilitating complex condition affecting men and women, but the knowledge gaps are salient. The condition impacts somatic, sexual, and mental health, as well as social, family, and work life. The complexity of the condition demands for a giant step away from traditional dualistic clinical approach.

Virtually isolated: social identity threat predicts social approach motivation via sense of belonging in computer-supported collaborative learning.

Collaboration improves multiple academic and social outcomes. Accordingly, computer-supported collaborative learning (CSCL) can be beneficial in distance education contexts to overcome the issues specific to online learning (e.g.

Physiotherapists' Treatment Strategies and Delineation of Areas of Responsibility for People With Musculoskeletal Conditions and Comorbidities in Private Physiotherapy Practice: A Qualitative Study.

Background: Patients with multiple chronic conditions, for example, musculoskeletal conditions and comorbidities, often receive inadequate and sometimes even contradictory care. Physiotherapists are well qualified to manage patients with musculoskeletal conditions and comorbidities due to their education and experience with rehabilitation; however, it is unknown which challenges they face when treating these patients.

Aim: To identify challenges, treatment strategies, and delineations of areas of responsibility among physiotherapists working in private physiotherapy practice when treating people with musculoskeletal conditions and comorbidities.

Modeling individual differences in vocabulary development: A large-scale study on Japanese heritage speakers.

This study examines when the vocabulary knowledge of Japanese heritage speakers (HSs; N = 427, M = 9.96, female = 213) begins to diverge from monolingual counterparts (N = 136, M = 6.69, female = 65) and what factors explain individual differences in HS development.