9 results match your criteria: "The American University in Cairo AUC Avenue[Affiliation]"

Article Synopsis
  • Cancer is a complex issue that requires new treatment strategies beyond traditional chemotherapy, which often has severe side effects and leads to drug resistance.
  • Essential oils (EOs), made of beneficial plant compounds, show potential as cancer-fighting agents, but their effectiveness is limited due to factors like instability and low targeted delivery.
  • Using nanoparticles and various nanosystems can improve the delivery and effectiveness of EOs in cancer treatment by enhancing absorption, controlling release, and targeting tumors more effectively.
View Article and Find Full Text PDF

Combining sonochemistry with phytochemistry is a modern trend in the biosynthesis of metallic nanoparticles (NPs), which contributes to the sustainability of chemical processes and minimizes hazardous effects. Herein, titanium dioxide (TiO) NPs were bioengineered using a novel and facile ultrasound-assisted approach utilizing the greenly extracted essential oil of . FTIR and UV-Vis spectrophotometry were used to confirm the formation of TiO NPs.

View Article and Find Full Text PDF

Despite the advancements in cancer therapies during the past few years, chemo/photo resistance, severe toxic effects, recurrence of metastatic tumors, and non-selective targeting remain incomprehensible. Thus, much effort has been spent exploring natural anticancer compounds endowed with biosafety and high effectiveness in cancer prevention and therapy. Gambogic acid (GA) is a promising natural compound in cancer therapy.

View Article and Find Full Text PDF

Improved antimicrobial activities of essential oils nanoencapsulated into hydroxypropyl-beta-cyclodextrins.

Nanoscale Adv

January 2024

Department of Chemistry, School of Sciences & Engineering, The American University in Cairo AUC Avenue, SSE # 1184, P.O. Box 74 New Cairo 11835 Egypt +20 02 2615 2559.

Natural antimicrobials have recently gained increasing interest over synthetic antimicrobials to overcome foodborne pathogens and food microbial contamination. Essential oils (EOs) obtained from resins (BO) were utilized for respiratory disorders, rheumatoid arthritis, malignant tumors, and viral infections. Like other EOs, the therapeutic potential of BO is hindered by its low solubility and bioavailability, poor stability, and high volatility.

View Article and Find Full Text PDF
Article Synopsis
  • The study developed copper oxide nanoparticles (CuO NPs) using essential oils from oleogum resin, applying microwave energy, and then loaded them with the anticancer drug carboplatin, creating a combination known as Cr@CuO NPs.
  • Characterization techniques like high-resolution electron microscopy and X-ray diffraction were used to analyze the properties of the synthesized nanoparticles, which showed effective release profiles and high entrapment efficiency for carboplatin.
  • Results indicated that Cr@CuO NPs exhibited significantly higher cytotoxicity against human colon cancer cells than either free carboplatin or CuO NPs alone, demonstrating their potential as a more effective cancer treatment through enhanced apoptosis and gene activity modulation.
View Article and Find Full Text PDF

Bovine tuberculosis (bTB) is considered a worldwide infectious zoonotic disease. causes bTB disease. It is one of the complex (MTBC) members.

View Article and Find Full Text PDF

Exploitation of expired cellulose biopolymers as hydrochars for capturing emerging contaminants from water.

RSC Adv

June 2023

Department of Chemistry, School of Sciences and Engineering, The American University in Cairo AUC Avenue, P. O. Box 74 New Cairo 11835 Egypt +202-2795-7565 +202-2615-2564.

Expired chemicals pose a potential environmental threat to humans and living organisms. Herein, we proposed a green approach whereby expired cellulose biopolymers were converted to hydrochar adsorbents and tested for removing the emerging pharmaceutical contaminants of fluoxetine hydrochloride and methylene blue from water. A thermally stable hydrochar was produced with an average particle size of 8.

View Article and Find Full Text PDF

Polymeric nanoparticles for dopamine and levodopa replacement in Parkinson's disease.

Nanoscale Adv

December 2022

Department of Chemistry, School of Sciences & Engineering, The American University in Cairo AUC Avenue, P. O. Box 74 New Cairo 11835 Egypt

As the world's population ages, the incidence of Parkinson's disease (PD), the second most common neurological ailment, keeps increasing. It is estimated that 1% of the global population over the age of 60 has the disease. The continuous loss of dopaminergic neurons and the concomitant brain depletion of dopamine levels represent the hallmarks of PD.

View Article and Find Full Text PDF

Betaine host-guest complexation with a calixarene receptor: enhanced anticancer effect.

RSC Adv

July 2021

Department of Chemistry, School of Sciences & Engineering, The American University in Cairo AUC Avenue, PO. Box 74 New Cairo 11835 Egypt +20 2 2795 7565 +20 2 2615 2559.

-Sulfonatocalix[]arenes have shown excellent potential for accommodating chemotherapeutic drugs through host-guest complexation and enhancing their anticancer activity. Betaine has been reported to exert an anticancer effect at high concentrations. In order to increase its concentration in cancer cells, we have complexed it with -SC4, which releases its content in an acidic environment typical of cancer tissue.

View Article and Find Full Text PDF