1 results match your criteria: "The Affinited Wenling Hospital of Wenzhou Medical College[Affiliation]"
[Clinical application of microarray technique to quantify the lamivudine-resistant gene mutant of hepatitis B virus].
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi
June 2007
The Affinited Wenling Hospital of Wenzhou Medical College, Wenling 317500, China.
Article Synopsis
- The study aimed to assess a new technique using gene microarray technology to measure lamivudine-resistant mutants of hepatitis B virus (HBV) in patients' serum.
- The research involved 51 patients on lamivudine treatment, monitoring them for 24 months with both microarray and traditional sequencing methods to identify resistance mutations.
- Results showed that 39% of patients developed resistance to lamivudine, with the microarray method being as accurate as traditional sequencing but more sensitive in detecting mixed infections.