Lysophosphatidic acid enhanced the osteogenic and angiogenic capability of osteoblasts via LPA1/3 receptor.

Lysophosphatidic acid is a serum-derived growth factor that is involved in wound healing. Although in its infancy, a growing body of evidence has demonstrated that lysophosphatidic acid exerts a potentially significant role in regulating bone cell biology. However, previous studies mainly focused on the osteoinductive potential of lysophosphatidic acid, its effects on bone tissue vascularization, another essential element during bone regeneration, remains ill-defined so far.

An in vitro study of the long non-coding RNA TUG1 in tongue squamous cell carcinoma.

Background: This study sought to study the expression of the long non-coding RNA (lncRNA) taurine-upregulated gene 1 (TUG1) in tongue squamous cell carcinoma (TSCC) and reveal its possible function.

Methods: qRT-PCR was used to evaluate 27 samples of fresh TSCC tissues and adjacent normal tongue tissues. siRNA technology was employed to downregulate TUG1 expression in CAL-27 and SCC-9 cell lines.

TUC338 Overexpression Leads to Enhanced Proliferation and Reduced Apoptosis in Tongue Squamous Cell Carcinoma Cells In Vitro.

Purpose: Long noncoding RNAs are closely related to the development of tumors. In this study, we explored the contribution of the long noncoding RNA TUC338 to cellular processes in tongue squamous cell carcinoma (TSCC).

Materials And Methods: First, we detected TUC338 expression using quantitative reverse transcription-polymerase chain reaction in 25 patients.

MALAT1 induces tongue cancer cells' EMT and inhibits apoptosis through Wnt/β-catenin signaling pathway.

Background: MALAT1 is recognized as an oncogenic lncRNA in various malignancies. However, its expression and function in oral tongue squamous cell carcinoma are still unknown. This study aims to investigate the expression and function of MALAT1 in TSCC tissues and cells.

[Effects of cetylpyridinium chloride buccal tablets on halitosis induced by oral conditions].

Objective: To investigate the effect of cetylpyridinium chloride buccal tablets on halitosis induced by oral conditions.

Methods: With Porphyromonas gingivalis, Prevotella intermedia and Fusobacterium nucleatum as the testing bacteria, the minimal inhibitory concentration (MIC) of cetylpyridinium chloride buccal tablets was determined using minute amount serial dilution test. The production of volatile sulfur compounds (VSCs) was measured using sulfide detector halimeter in the anaerobic bacteria culture at 4 and 8 h after addition of the tablets.

[Research on anatomy of posterior tooth in the Beagle dog and mini-screw implant implantation].

Objective: The morphological characteristics of posterior tooth in the Beagle dog were investigated in order to provide reference to mini-screw implant (MSI) implantation in the root furcation site.

Methods: Seventy posterior teeth of five Beagle dogs were collected and measured as follows: First, the greatest mesio-distal diameter AB of the crown was measured, which was perpendicular to the tooth long axis. Second, mesial cusp of maxillary posterior tooth or central cusp of mandibular was marked as the piont C, and CD which was equal and perpendicular to AB was drawn.