[Establishment of An Animal Model of Acute B Lymphoblastic Leukemia with Minimal Residual Disease].

Objective: To establish an animal model of acute B lymphoblastic leukemia (B-ALL) with minimal residual disease.

Methods: The transplanted tumor was formed by subcutaneous injection of 2×10 Nalm-6 cells, and the body weight, activity status and tumor formation status of nude mice were observed. Peripheral blood, bone marrow, liver and spleen and other tissues of nude mice were taken for pathological examination to understand whether the success of subcutaneous modeling was accompanied by systemic metastasis.