4 results match your criteria: "The Affiliated Drum Town Hospital of Nanjing University Medical School[Affiliation]"

Objective: To provide radiographic parameters for optimal placement of posterior second sacral alar iliac (S2AI) screw for instrumentation and fusion of scoliosis to the second sacral level in a Chinese population.

Methods: S2AI screw trajectories were mapped on three-dimensional computed tomography (3DCT) reconstructions of 60 normal adult pelvises. 1 mm inferior and 1 mm lateral to the S1 dorsal foramen were chosen as the entry point, and ideal S2AI screw trajectories were explored by rotating and cutting the 3D pelvis, ensuring that the trajectories were of maximum length and width.

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Background: It has been recognised that genetic or hereditary factors may contribute to the aetiology of adolescent idiopathic scoliosis (AIS). Recently, two linkage analyses have identified 19p13.3 as the candidate region for AIS.

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Article Synopsis
  • The study aimed to investigate the association between the MTNR1A gene and adolescent idiopathic scoliosis (AIS) to see if genetic variations affect susceptibility or severity of the condition.
  • Previous research suggested melatonin pathways might play a role in AIS, sparking interest in the MTNR1A gene after findings about the MTNR1B gene's involvement.
  • The results indicated no significant differences in genotype and allele frequencies between AIS patients and controls, suggesting that MTNR1A gene polymorphisms do not impact the occurrence or severity of AIS.
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Unlabelled: Many studies have demonstrated the role of melatonin in the etiology of AIS. Previous studies have shown that there is no evidence of mutations in the melatonin receptor 1A gene in AIS patients. In this study, we have examined the role of melatonin receptor 1B in predisposition for AIS.

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