2 results match your criteria: "The Affiliated Baoan Hospital of Nanfang Medical University[Affiliation]"
ACE2 activity was increased in atherosclerotic plaque by losartan: Possible relation to anti-atherosclerosis.
J Renin Angiotensin Aldosterone Syst
June 2015
Department of Cardiology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China Department of critical care Medicine, the Affiliated baoan Hospital of Nanfang Medical University, Shenzhen Departmentof Pathophysiology, Shandong University School of Medicine, Jinan, Shandong, China
Introduction: Angiotensin-converting enzyme 2 (ACE2) is a new member of the renin-angiotensin system (RAS) and it has been proposed that ACE2 is a potential therapeutic target for the control of cardiovascular disease. The effect of losartan on the ACE2 activity in atherosclerosis was studied.
Methods: Atherosclerosis was induced in New Zealand white rabbits by high-cholesterol diet for 3 months.
[An experimental study of expression of angiotension converting enzyme 2 in myocardium and effect of telmisartan treatment in pressure-overloaded rats].
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
April 2008
Department of Cardiology, The Affiliated Baoan Hospital of Nanfang Medical University, Shenzhen 518101, Guangdong, China.
Objective: To study the effect of hypertension and telmisartan treatment on the protein and gene expression of cardiac angiotensin-converting enzyme 2 (ACE2) in pressure-overloaded rats.
Methods: Coarctation of suprarenal abdominal aorta was reproduced in 8 week-old male Sprague-Dawley (SD) rats and then randomized into 4 groups, including a sham group (n=15), a suprarenal aortic coarctation group (model group, n=12), a suprarenal aortic coarctation with low-dose Telmisartan treatment group (low-dose group, 2 mgxkg(-1)xd(-1), n=11) and a suprarenal aortic coarctation with high-dose Telmisartan treatment group(high-dose group, 10 mgxkg(-1)xd(-1), n=13). Telmisartan or equivalent amount of normal saline was gavaged 24 hours before the operation and once every day afterwards for 3 weeks.