Subthreshold depression among diabetes patients in Beijing: Cross-sectional associations among sociodemographic, clinical, and behavior factors.

Background: This study explores the prevalence of subthreshold depression (SubD) and its association with factors in type 2 diabetes mellitus (T2DM) patients.

Methods: This cross-sectional study involved 808 outpatients with T2DM from ten hospitals in Beijing between September 2015 and January 2016. All participants completed the Patient Health Questionnaire 9-item (PHQ-9) to evaluate depressive status, with scores between 5 and 14 considered SubD.

[Vascularized pedicle iliac crest for the repair of bone and soft tissue defect of lower extremity].

Objective: To study the role of transplantation of the vascularized pedicle iliac crest for the repair of bone and soft tissue defect of lower extremity.

Methods: The vascularized pedicle iliac crest was designed for the repair of bone and soft tissue defect of lower extremity according to anatomic feature of leg and foot. Skin graft was used for coverage of the iliac flap.

[The use of dynamic axial external fixator with modified technique in Pilon fractures of tibial].

Objective: To retrospectively analyses the results of dynamic axial external fixator with modified technique in the treatment of severely Pilon fractures.

Methods: From July 2000 to February 2003, 14 patients with severely Pilon fractures were treated with dynamic axial external fixator inserted with modified technique combined with limited open reduction and internal fixation with screws and Kirschner wires, with two distal external pins inserted into talus and calcaneus respectively so that the rotation axis of distal clamp was coincided with that of ankle joint. All patients were young or middle-aged people from 20 y to 52 y (average 38 y).

[The pathogenesis of discogenic low back pain].

Objective: To study the pathogenesis of the pain of discography and the discogenic low back pain.

Methods: 19 specimens of lumbar intervertebral discs from 17 patients with discogenic low back pain during posterior lumbar interbody fusion, and 12 physiologically aging discs and 10 normal control discs were collected to investigate the morphologic features and innervation containing neuropeptides substance P (SP), neural filament (NF), and vasoactive-intestinal peptide (VIP).

Results: The distinct morphologic characteristic of the disc from the patient with discogenic low back pain was the formation of the strip zone of vascularized granulation tissue from the nucleus pulposus to the outer part of the annulus fibrosus in which there was one or several fissures.

[The change in CD14 mRNA expression in rats with scald injury and Staphylococcus aureus challenge].

Objective: To investigate the potential role and changes in CD14 in postburn Staphylococcus aureus sepsis.

Methods: Wistar rats were subjected to a 20% total body surface area (TBSA) full-thickness thermal injury and followed by Staphylococcus aureus challenge. Plasma and tissue samples from liver, kidneys, lungs and heart were collected to determine endotoxin (lipopolysaccharide, LPS) levels and CD14 mRNA expression.

[Changes in skeletal muscle protein metabolism in burned rats with sepsis and the role of glucocorticoid in skeletal muscle proteolysis].

Objective: To study the effects of glucocorticoid on skeletal muscle protein metabolism in burn sepsis and its possible mechanism.

Methods: The rats were randomly divided into four groups with 15 rats in each group. Group B, 30% TBSA full-thickness burn was produced on the back and endotoxin (6 mg/kg bw) was given intraperitoneally after the injury to simulate burn sepsis.