2 results match your criteria: "The 1st Affiliated Hospital of Zhengzhou University Zhengzhou[Affiliation]"
Let-7a inhibits migration of melanoma cells via down-regulation of HMGA2 expression.
Am J Transl Res
September 2016
Department of Neurology, Key-Disciplines Laboratory Clinical Medicine Henan, The 1st Affiliated Hospital of Zhengzhou University Zhengzhou 450052, Henan, China.
This study aimed to investigate the effects of exosomes derived from BM-MSCs transduced with let-7a on B16f10 cells and BM-MSCs. BM-MSCs were transduced with let-7a and the exosomes of them were isolated for further culture of B16f10 cells and BM-MSCs. The migration of B16f10 cells were detected by transwell, proliferation of B16f10 cells and BM-MSCs was examined by MTT method, HMGA2 expression was measured by western blot.
View Article and Find Full Text PDFMicroRNA-365 inhibits growth, invasion and metastasis of malignant melanoma by targeting NRP1 expression.
Int J Clin Exp Pathol
April 2016
Plastic Surgery, The 1st Affiliated Hospital of Zhengzhou University Zhengzhou, China.
Objective: The role of miR-365 in cancer cells seemed controversial in previous studies. We thereby in this article aimed to define the role of miR-365 in malignant melanoma (MM) pathogenesis.
Methods: We detected miR-365 expression in malignant melanoma cell lines and then investigated the effects of miR-365 on the metastasis and malignancy of melanoma cells.