Repair of bone defect of the lateral forefoot by double segment triangular fibula flap with vascular pedicle: A case report.

To expound the clinical effect of a new operation by transplanting double segment triangular fibula flap with vascular pedicle to repair the forefoot with lateral bone defect, and to study how to improve the operation method in the following stage. The inclusion criteria: More than 2 phalangeal and metatarsal bones defects of the lateral forefoot, widespread skin and soft tissue defects on pelma and dorsal foot, and destruction of the anterior aspect of foot arch, which seriously affects the foot function. There was one case of clinical application in November 2014.

Retinal changes following rapid ascent to a high-altitude environment.

PurposeTo determine what impact rapid ascension to a high-altitude environment has on the retina with the aim of preventing and treating high-altitude oculopathy.Patients and methodsParticipants in the study were members of the Chinese military assigned to the high-altitude environment of the Tibetan plateau. Ninety-one participants were enrolled in the study.

Syringic acid protects retinal ganglion cells against H2O2-induced apoptosis through the activation of PI3K/Akt signaling pathway.

Oxidative damage is believed to contribute to the pathogenesis of diabetic retinopathy. Syringic acid (SA), a naturally occurring O-methylated trihydroxybenzoic acid monomer extracted from Herba dendrobii, has been shown to possess antioxidant activity. However, the effects of SA on apoptosis of retinal ganglion cells (RGCs) induced oxidative damages have not yet been explored.