Effects of treadmill running on anxiety- and craniofacial pain-like behaviors with histone H3 acetylation in the brain of mice subjected to social defeat stress.

This study examined the effects of treadmill running (TR) regimens on craniofacial pain- and anxiety-like behaviors, as well as their effects on neural changes in specific brain regions of male mice subjected to repeated social defeat stress (SDS) for 10 days. Behavioral and immunohistochemical experiments were conducted to evaluate the impact of TR regimens on SDS-related those behaviors, as well as epigenetic and neural activity markers in the anterior cingulate cortex (ACC), insular cortex (IC), rostral ventromedial medulla (RVM), and cervical spinal dorsal horn (C2). Behavioral responses were quantified using multiple tests, while immunohistochemistry measured histone H3 acetylation, histone deacetylases (HDAC1, HDAC2), and neural activity markers (FosB and phosphorylated cAMP response element-binding protein (pCREB).

sp. nov., isolated from tree bark ( Chev.) and its antioxidant activity.

A Gram-stain-positive, facultatively anaerobic, rod-shaped strain, designated SPB1-3, was isolated from tree bark. This strain exhibited heterofermentative production of dl-lactic acid from glucose. Optimal growth was observed at 25-40 °C, pH 4.

New α-Glucosidase Inhibitors from Vietnamese Garcinia schomburgkiana Fruits.

The chemical investigation of the fruits of Garcinia schomburgkiana growing in Vietnam led to the isolation of a new anofinic acid derivative, 5-hydroxy-8-methoxyanofinic acid (1), a new xanthone, xanthoschome C (2), and a known synthetic phenolic analogue, 4-(2-hydroxybenzyl)-2-(4-hydroxybenzyl) phenol (3), along with seven known xanthones (4-10). The structures of all isolated compounds were determined using spectroscopic techniques (NMR and MS), in conjunction with comparison to existing literature data. All isolated compounds were assessed for their α-glucosidase inhibitory activity and showed significant inhibition, with IC50 values ranging from 12.

A comparative study of curve flexibility assessment in supine traction, push-prone and push-prone traction radiographs in adolescent idiopathic scoliosis.

Study Design: A prospective comparative study.

Objectives: To compare the curve flexibility in adolescent idiopathic scoliosis (AIS) using supine traction push-prone and push-prone traction radiographs and to determine which method is more effective in predicting the postsurgical correction.

Background: Preserving spinal motion is one of the critical objectives in adolescent idiopathic scoliosis (AIS) surgery.

Fuzzy logic modelling of the pollution pattern of potentially toxic elements and naturally occurring radionuclide materials in quarry sites in Ogun State, Nigeria.

The accumulation pattern of some inorganic pollutants in quarry sites around Ogun State was modeled using a Fuzzy comprehensive assessment (FCA). Potentially toxic elements (PTEs) and naturally occurring radionuclides materials (NORMs) were assessed from soil samples collected from ten quarry sites in three districts (Odeda, Ajebo, and Ijebu Ode) in Ogun State. Three (3) NORMs ( K, U, Th) were assessed using gamma spectrometer with a NaI detector while ten (10) PTEs (As, Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb, and Zn) were determined by digestion method using Inductively coupled plasma optical emission spectrophotometer.

Mutations in Aristolochene Synthase Promote Hydroxylation of Aristolochene in Aspergillus oryzae.

A terpene synthase gene (mtas) from Menisporopsis theobromae BCC 4162 was heterologously expressed in Aspergillus oryzae NSAR1, resulting in the production of (+)-aristolochene. Mutations were introduced in MtAS at aromatic residues (Y83, F103, F169, and W323) surrounding the active site, which are critical for precursor cyclisation and intermediate stabilisation during aristolochene biosynthesis. Transformants harbouring mutated mtas, specifically F103W, F169A and F169W, produced (2R,4S,5R,7S)-2-hydroxyaristolochene as the major product, along with aristolochene and other tentative metabolites, including germacrene A and sesquiterpenoids.

Spatial association of socioeconomic and health service factors with antibiotic self-medication in Thailand.

Antibiotic Self-Medication (ASM) is a major contributing factor to Antimicrobial Resistance (AMR) that can lead to both mortality and long-term hospitalizations. High provincial ASM proportions associated with mortality due to AMR have been observed in Thailand but there is a lack of studies on geographic factors contributing to ASM. The present study aimed to quantify the distribution of ASM in Thailand and its correlated factors.

Chromosome-level assembly of basil genome unveils the genetic variation driving Genovese and Thai aroma types.

Basil, Ocimum basilicum L., is a widely cultivated aromatic herb, prized for its culinary and medicinal uses, predominantly owing to its unique aroma, primarily determined by eugenol for Genovese cultivars or methyl chavicol for Thai cultivars. To date, a comprehensive basil reference genome has been lacking, with only a fragmented draft available.

Development of heat sealable film from tapioca and potato starch for application in edible packaging.

This study aimed to fabricate edible films from tapioca (T) and potato (P) starch, assessing their physicochemical properties and biodegradation across different ratios (T100P0, T70P30, T50P50, and T30P70). The films underwent evaluation for moisture content, thickness, water vapor permeability, and color values. T100P0 and T30P70 formulations exhibited the highest film transparency at 43.

Utilization of rice pasta by-products as the substrate for vinegar fermentation.

Unlabelled: The aim of this study was to utilize four rice pasta by-products (RPB), including white rice pasta, black jasmine rice pasta, red jasmine rice pasta and brown rice pasta, to ferment into four vinegars. The dynamic variations during fermentation and their quality were evaluated. During alcoholic fermentation, the saccharified substrates were fermented with for 12 days, resulting in an alcohol yield of approximately 10% (v/v) after 4 days of fermentation.

Dosimetry Assessment of Potential Hazard from Visible Light, Especially Blue Light, Emitted by Screen of Devices in Daily Use.

Visible light has been considered to have minimal impact on the skin. However, the increasing use of electronic devices has led to a significant increase in exposure to visible light, especially blue light. We measured the irradiance (mW/cm) and estimated dose (J/cm) of visible light and blue light emitted from various electronic devices including smartphones, tablets and computers.

Lymphomatoid Papulosis Type E With T-Cell Receptor Gamma Positivity.

Lymphomatoid papulosis (LyP) is currently categorized as a primary lymphoproliferative disorder that follows a chronic, recurrent clinical course. The diagnosis of LyP is mainly based on clinical presentation and histopathological correlation. Six subtypes of LyP have been described and recognized, each with different histological features and sometimes distinct clinical presentations.

Aortoiliac arterial thrombosis and renal artery stenosis in a patient with neonatal multisystem inflammatory syndrome: a case report and review of literature.

Background: Multisystem inflammatory syndrome in neonates (MIS-N) is a rare condition thought to be associated with prenatal exposure to maternal severe acute respiratory syndrome coronavirus 2 infection. This immune-mediated hyperinflammation has been described in neonates with multiorgan dysfunction, including cardiopulmonary, encephalopathy, coagulopathy, and vascular complications. However, renovascular complications in MIS-N are rare.

Effect of Fluoride-incorporated Bioactive Glass Toothpaste on Remineralization of Primary Enamel Lesions: An Study.

Aims: This study aimed to evaluate the enamel remineralization effect of fluoride-incorporated bioactive glass (F-BG) toothpaste on artificial subsurface caries in primary teeth.

Materials And Methods: Forty sound primary maxillary incisors were subjected to a demineralizing solution for four days to induce artificial enamel caries. The teeth were randomly divided into four experimental groups ( = 10 per group): Group I, F-BG toothpaste (530 ppm fluoride) (BiominF); Group II, 0.

The Impact of Online Learning and Health Behavior on Mental Health among Thai Dental Students during the COVID-19 Era.

Aims: This study aimed to investigate the impact of online learning on the mental health and health behaviors of Thai dental students during the coronavirus disease 2019 (COVID-19) pandemic.

Materials And Methods: A cross-sectional analytical study was conducted among Thai dental students from first to sixth year who had been engaged in online learning during the COVID-19 period. A total of 440 students participated.

Etiology of Hospital-Acquired Pneumonia (HAP) and Ventilator-Associated Pneumonia (VAP) in Tertiary-Care Hospitals in Thailand: A Multicenter, Retrospective Cohort Study.

Purpose: To describe the top three causative organisms of hospital acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) in Thailand.

Patients And Methods: This multi-center retrospective cohort study included HAP/VAP patients hospitalized in 2019 in three university-affiliated hospitals and a private hospital in Bangkok, Thailand. Medical records of patients with a documented diagnosis of nosocomial pneumonia (NP) were systematically reviewed to collect data on demographic, clinical, microbiological, and 30-day readmission due to NP.

Taxonomic notes on the genus Breuning & de Jong, 1941 (Coleoptera, Cerambycidae) with a generic and specific synonym.

Taxonomic notes on the genus Breuning & de Jong, 1941 are presented. The genus Breuning, 1966 is synonymized with , and Breuning, 1966 is recognized as a junior synonym of Breuning & de Jong, 1941. Additionally, is redescribed, and Breuning, 1973 is formally reported from China, Vietnam, Thailand, and India for the first time.

Optimizing Young Jackfruit ( Lam.) Processing for Plant-Based Meatballs: Impact of Thermal Treatments on Quality Parameters and Organoleptic Properties.

As global demand for plant-based foods increases due to their nutritional and environmental benefits, young jackfruit () is emerging as a promising meat alternative. This study evaluates the effects of heat treatments-specifically blanching for 5 min and boiling for 15, 30, and 45 min-on the quality and sensory attributes of jackfruit-based meatballs. The results indicate consistent color values ( , , and ) across the samples, with values ranging from 53.

A systematic review of Streptococcus Mutans and Veillonellae species interactions in dental caries progression: Positive or Negative impact?

Background: The interaction between Streptococcus mutans (S. mutans) and Veillonella species (Veillonella spp.) is unclear.

Knowledge, Attitude, Awareness, and Practice Regarding Mites Among the Thai Population.

Background: mites are common ectoparasites in humans and can cause various skin disorders known as demodicosis, ranging from nonspecific facial dermatitis to conditions resembling eczema, seborrheic dermatitis, folliculitis, and acne. Overgrowth of these mites can lead to pityriasis folliculorum, perioral dermatitis, blepharitis, and rosacea, significantly impacting skin health. This study aims to investigate the knowledge, attitude, awareness, and practice regarding mites in the Thai population and analyze the influencing factors associated with these aspects.

Artificial intelligence-powered innovations in periodontal diagnosis: a new era in dental healthcare.

Background: The aging population is increasingly affected by periodontal disease, a condition often overlooked due to its asymptomatic nature. Despite its silent onset, periodontitis is linked to various systemic conditions, contributing to severe complications and a reduced quality of life. With over a billion people globally affected, periodontal diseases present a significant public health challenge.

Lanostane Triterpenes, Flavanones and Acetogenins from the Roots of and Their Cytotoxic Activity.

Our phytochemical investigation of the roots of led to the isolation of two new lanostane triterpenes, 3-acetylpolycarpol () and 15-acetylpolycarpol (), as well as 15 known compounds (-). The structures of the isolated compounds were elucidated by an analysis of spectroscopic data. Compounds - were tested against nonsmall cell lung cancer cells (A549) and human cervical carcinoma cells (HeLa) using an MTT assay.

Enhanced Ion Solvation and Conductivity in Lithium-Ion Electrolytes via Tailored EMC-TMS Solvent Mixtures: A Molecular Dynamics Study.

The development of stable, high-performance electrolytes is essential to addressing the safety concerns and limited lifespan caused by the thermal and chemical instability of traditional organic carbonate-based electrolytes in lithium-ion batteries (LIBs). This study examined the potential of mixed solvent systems, specifically ethyl methyl carbonate (EMC) and tetramethylene sulfone (TMS), to modify ion solvation and improve ionic conductivity in LIB electrolytes. Through molecular dynamics simulations, we investigated the solvation structure and transport properties of lithium ions (Li) in these solvent environments.

Electrochemical Monitoring of Vitamins B and C in Environmental Matrices with an Oligo Diaminotriazole Electrode.

Chemical polymerization/oligomerization opens numerous opportunities, from fundamental materials research to practical applications in catalysis, energy, sensing, and medicine. The electrochemical detection of vitamins B (folic acid) and C (ascorbic acid) requires new approaches because of low selectivity, electrode fouling, and interference from other chemicals. As an excellent material for long-term vitamin detection, oligo 3,5-diamino-1,2,4-triazole (oligo DAT) enhances the sensitivity, selectivity, and stability of sensors by creating a stable, conductive layer that facilitates electron transfer and reduces interference from common substances like glucose or uric acid.

Chiral Recognition of Butylone by Methylated β-Cyclodextrin Inclusion Complexes: Molecular Calculations and Two-Level Factorial Designs.

The integration of molecular docking and AM1 calculations has elucidated the complexation behavior of butylone enantiomers with methylated β-cyclodextrin derivatives. Our study reveals that butylone can adopt two distinct conformations within the β-cyclodextrin cavity, with one conformation being preferentially stabilized due to its favorable binding energy. This conformation preference is influenced by the methylation at the O2, O3, and O6 positions of β-cyclodextrin, which significantly affects complex stability and solvation properties.