850 results match your criteria: "Texas Tech University Health Sciences Center El Paso[Affiliation]"

Purpose: This study aimed to describe stroke survivors' experiences receiving telemedicine visits at the Lone Star Stroke Consortium during the COVID-19 pandemic.

Materials And Methods: A qualitative descriptive phenomenological design was applied to gather patients' telemedicine experiences through in-depth interviews, using a study guide. Audio-recorded interviews were conducted via ZOOM and transcribed verbatim.

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Article Synopsis
  • A nine-year-old boy with trisomy 21 and end-stage renal disease showed signs of peritonitis linked to his peritoneal dialysis catheter.
  • After initial antibiotic treatment failed, the catheter was surgically removed, revealing a non-tuberculous mycobacterial infection that improved his symptoms.
  • He later transitioned to hemodialysis and received a successful kidney transplant eight months later, highlighting the importance of considering atypical infections in similar cases.
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Aspiration of Right Atrial Tumor Metastasis.

JACC Case Rep

September 2024

Department of Interventional Cardiology, Memorial Medical Center, Las Cruces, New Mexico, USA.

A 72-year-old man with cirrhosis had undiagnosed hepatocellular carcinoma with distant metastasis occupying nearly the entire right atrium. He was a poor surgical candidate because of his bleeding risks and advanced liver cirrhosis. He successfully underwent urgent large-bore aspiration thrombectomy under simultaneous echocardiography and fluoroscopy, thus leading to a diagnosis of metastatic malignant disease.

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Unlabelled: The current investigation involved the isolation of 13 endophytic fungi from sp. collected in Himachal Pradesh, India. Among these, isolate PAT-3 produced 195.

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2-methoxyestradiol inhibits the malignant behavior of triple negative breast cancer cells by altering their miRNome.

Front Oncol

September 2024

Center of Emphasis in Cancer Research, Department of Molecular and Translational Medicine, Texas Tech University Health Sciences Center El Paso, Paul L. Foster School of Medicine, El Paso, TX, United States.

Article Synopsis
  • Triple-negative breast cancer (TNBC) currently lacks effective targeted treatments, but the study explores the anti-cancer effects of 2-methoxyestradiol (2ME2), previously shown to affect mammary cancer.
  • The research involved testing 2ME2 on TNBC cell lines, revealing that it significantly inhibited cell growth, induced apoptosis, and interrupted the cell cycle, while also reducing cell migration and invasion.
  • The findings indicate that 2ME2 alters miRNA expression relevant to cancer growth, suggesting its potential as a powerful treatment option for TNBC by targeting key cancer processes.
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  • The study examined how first-degree family history of cancer affects patients with stage I endometrial cancer by reviewing patient records from 1990 to 2016.
  • It compared demographic information, tumor characteristics, treatment plans, and outcomes between patients with and without a family history of cancer, finding that familial history is linked to being older and having longer time to recurrence.
  • The results indicated that while patients with a positive family history tended to have similar tumor characteristics, they experienced a longer time to recurrence, especially with maternal and sister's cancer history being the most prevalent.
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  • Pharmacologic therapies for gastroparesis (GP) show limited effectiveness, making it hard to predict patient responses to treatments.
  • The study developed a machine learning model to assess the likelihood of patients with GP-like symptoms benefiting from prokinetics and/or neuromodulators based on various health metrics.
  • Results indicated that the model could accurately predict responses, especially among patients only taking prokinetics, offering a potential tool for improving treatment strategies if validated in future research.
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Coccidioidomycosis is endemic in the southwestern United States, Central America, and South America. Coccidioidomycosis has a variety of clinical presentations. Coccoidal meningitis is a feared form of disseminated coccidioidomycosis with high mortality and mobility rates.

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Increases in amyloid-β42 slow cognitive and clinical decline in Alzheimer's disease trials.

Brain

October 2024

James J. and Joan A. Gardner Family Center for Parkinson's disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, OH 45219, USA.

Article Synopsis
  • The study explores the relationship between changes in cerebrospinal fluid (CSF) Aβ42 levels and cognitive outcomes in Alzheimer's disease (AD) patients treated with anti-amyloid-β drugs.
  • Higher CSF Aβ42 levels were found to be associated with a slower decline in cognitive performance as measured by standardized assessment scales.
  • These findings suggest that increases in CSF Aβ42 could indicate a potentially beneficial effect of anti-Aβ therapies on cognitive impairment and clinical progression in AD.
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Adnexal torsion during pregnancy is rare and is complicated by ambiguous symptoms and often nonspecific imaging findings. Differential diagnoses of torsion include a ruptured ovarian cyst, tubo-ovarian abscess, and appendicitis. A low threshold for the recommended surgical laparoscopy is necessary to avoid delayed diagnosis and fetal or maternal complications.

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Colorectal cancer (CRC) is the leading cause of cancer-related mortality among U.S. Hispanics, with screening proven to decrease both incidence and mortality.

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Background: Frailty has been identified as an independent predictor of mortality in the elderly. We investigated the effects of frailty status on in-hospital outcomes of acute colonic diverticulitis (ACD) in the elderly, using the Hospital Frailty Risk Score.

Methods: We used the National Inpatient Sample (NIS) databases from 2016-2020 to identify patients aged ≥75 years hospitalized with ACD.

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Thyrotoxic periodic paralysis (TPP) is a clinical condition characterized by hypokalemia, muscle paralysis, and hyperthyroidism. TPP can be challenging to diagnose due to its low disease prevalence and the similarity of paralysis to other common conditions. Through this case report, we highlight the importance of considering hyperthyroidism as a cause of recurrent attacks of muscle paralysis, particularly in the setting of other signs of hyperthyroidism.

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Background: Breast cancer (BC) affects racial and ethnic groups differently, leading to disparities in clinical presentation and outcomes. It is unclear how Hispanic ethnicity affects BC outcomes based on geographic location and proximity to the United States (U.S.

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Article Synopsis
  • - A 63-year-old woman arrived at an emergency room experiencing dizziness, palpitations, and low blood pressure; she was diagnosed with ventricular tachycardia and electrolyte imbalances (low magnesium and calcium levels).
  • - Despite treatment with IV amiodarone and magnesium, her tachycardia only resolved after her serum calcium levels were corrected.
  • - The patient had a history of left ventricular dysfunction discovered 19 years earlier but was unaware and not on any medication; the case suggests a possible link between her underlying heart condition and the rare occurrence of hypocalcemia-related ventricular tachycardia.
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As the incidence of subdural hematoma is increasing, it is important to understand symptomatology and clinical variables associated with treatment outcomes and mortality in this population; patients with subdural hematoma were selected from the National Inpatient Sample (NIS) Database between 2016 and 2020 using International Classification of Disease 10th Edition (ICD10) codes. Moderate-to-severe subdural hematoma patients were identified using the Glasgow Coma Scale (GCS). Multivariate regression was first used to identify predictors of in-hospital mortality and then beta coefficients were used to create a weighted mortality score.

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Previously, many studies have reported changes in the gut microbiota of patients with colorectal cancer (CRC). While CRC is a well-described disease, the relationship between its development and features of the intestinal microbiome is still being understood. Evidence linking enrichment in colorectal tumor tissue has prompted the elucidation of various molecular mechanisms and tumor-promoting attributes.

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An 11-Fold Higher Risk of Incident Mild Cognitive Impairment With Hispanic Ethnicity and Baseline Neuropsychiatric Symptoms.

J Neuropsychiatry Clin Neurosci

August 2024

Department of Psychiatry, Division of Geriatric Psychiatry and Behavioral Neurosciences (Salazar), and Department of Molecular and Translational Medicine, Division of Biostatistics and Epidemiology (Dwivedi, Alvarado), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso; Department of Psychiatry, School of Medicine, University of Texas Rio Grande Valley, Edinburg, Texas (Escamilla).

Objective: Neuropsychiatric symptoms (NPSs) have been linked to cognitive decline. This study explored ethnic differences and the effects of baseline NPSs on incident mild cognitive impairment (MCI) among 386 Hispanic and non-Hispanic participants from the Texas Harris Alzheimer's Research Study.

Methods: Data on NPSs from the Neuropsychiatric Inventory Questionnaire were available for all participants.

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Background And Objectives: Craniosynostosis can lead to progressive cranial and skull base deformities and can be associated with increased intracranial pressure (ICP), ophthalmological manifestations, behavioral changes, and developmental delay. Most published data on the incidence of elevated ICP include older children undergoing open surgical correction. Endoscopic-assisted release of fused sutures with postoperative helmet therapy is an established method for managing craniosynostosis presenting at an early age; however, the immediate effect of this approach on ICP in a young cohort has not been previously reported.

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Introduction: Amphetamine-based medications such as Adderall, used for the treatment of attention deficit-hyperactivity disorder (ADHD), may theoretically elicit angle closure through their adrenergic mechanisms. The relationship between the use of implantable collamer lenses (ICLs) and angle closure has been extensively investigated based on appropriate vault and lens sizing and postoperative changes in the anterior chamber angle (ACA) and corneal morphology. This case reflects a synergistic impact from both Adderall use and ICL implantation for the proposed mechanism of angle closure.

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The Mediation Pathway Linking Dental Caries and Academic Performance in Children.

Caries Res

August 2024

Biostatistics Unit, School of Dental Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.

Introduction: There is little discussion in the literature on the pathway linking oral health problems and academic performance (AP) in children. This study investigated the hypothesis that the influence of dental caries on academic performance is mediated through toothache and impacted sleep and study activities.

Methods: This cross-sectional study on children aged 12-14 years collected data on the exposure (decayed tooth index), outcome (school examination results), and mediator (school absence due to toothache, and oral health impact on sleep and study performances using the Child-Oral Impact on Daily Performance instrument) variables.

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Background: Supracondylar humerus (SCH) fractures are some of the most common fractures in pediatric patients with surgery typically consisting of either open or closed reduction with internal fixation. The aim of this meta-analysis was to identify patient, injury, and administrative factors that are associated with treating pediatric SCH fractures with open techniques.

Methods: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, PubMed and CINAHL database searches were conducted for studies from 2010 to 2023 that made direct comparisons between open reduction and internal fixation (ORIF) and closed reduction and percutaneous pinning (CRPP) for treating SCH fractures in the pediatric population.

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Hurricanes, as one of the most devastating natural disasters, significantly impact the public's health, causing both physical injuries and long-lasting mental health issues. Although substantial research has focused on hurricane-related injuries, this study aims to synthesize findings from recent literature, specifically evaluating the 10 most recent hurricanes, to identify research gaps and inform future studies. This scoping review, conducted in accordance with PRISMA-Scr guidelines, assessed studies from PubMed, CINAHL, Cochrane databases, and Medline as of February 2024.

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Introduction: In 2023, a group of experts proposed that a definition of major bleeding in pharmaceutically anticoagulated patients be used in all snakebite trials. This includes bleeding that results in death, is life-threatening, causes chronic sequelae, or consumes major healthcare resources, including bleeding into a major area or hemoglobin concentration decrease ≥20 g/L. We hypothesized that a decline in hemoglobin concentration ≥20 g/L is common but rarely clinically significant in our population of Arizona rattlesnake bite patients.

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The Street Medicine Auto-refraction Technology Study: A Model for Screening and Treating Refractive Error in Persons Experiencing Homelessness.

Am J Ophthalmol

July 2024

Division of Laser and Eye Surgery, Minnesota Eye Institute, Alexandria, Minnesota (P.N.); Department of Surgery, Texas Tech University Health Sciences Center El Paso, El Paso, Texas (P.N.), USA.

Purpose: The Street Medicine Auto-Refraction Technology study is an efficient and cost-effective treatment of refractive error (RE) and identification of potential non-RE pathology in people experiencing homelessness (PEHs).

Design: Outreach evaluation for diagnosis and treatment.

Methods: The internal medicine physicians/staff team used a protocol designed by ophthalmology to screen and treat PEHs.

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