765 results match your criteria: "Texas College of Osteopathic Medicine[Affiliation]"

The facial and transverse facial arteries supply blood to the superficial structures of the face. Understanding these arterial variations is essential for optimizing surgical planning and outcomes, especially in invasive facial procedures. A 78-year-old male cadaveric dissection documented variations in facial and transverse facial arteries.

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Leveraging Large Language Models in Radiology Research: A Comprehensive User Guide.

Acad Radiol

January 2025

Department of Radiology, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL 33431 (M.R.). Electronic address:

Large Language Models (LLMs) such as ChatGPT have been increasingly integrated into radiology research, revolutionizing the research landscape. The Radiology Research Alliance (RRA) of the Association for Academic Radiology (AAR) has convened a Task Force to develop this guide to help radiology researchers responsibly adopt LLM technologies. LLMs can improve various phases of the research process by helping to automate literature reviews, generate research questions, analyze complex datasets, and draft manuscripts.

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We present a rare case of pseudohyponatremia in a 20-year-old male patient with adult T-cell acute lymphoblastic leukemia (ATLL). The patient was admitted for a mediastinal mass with superior vena cava syndrome and was receiving pegaspargase therapy. The pseudohyponatremia was found to be secondary to hypertriglyceridemia associated with the pegaspargase treatment.

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There is a pressing need for accessible biomarkers with high diagnostic accuracy for Alzheimer's disease (AD) diagnosis to facilitate widespread screening, particularly in underserved groups. Saliva is an emerging specimen for measuring AD biomarkers, with distinct contexts of use that could complement blood and cerebrospinal fluid and detect various analytes. An interdisciplinary, international group of AD and related dementias (ADRD) researchers convened and performed a narrative review of published studies on salivary AD biomarkers.

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Background: This study describes the gender and racial/ethnic trends in academic physical medicine and rehabilitation (PM&R) and the shifts that have taken place in more than 4 decades.

Objective: To gauge the diversity in gender and race/ethnicity across academic degrees, academic ranks, chair positions, and tenure status in the academic workforce of PM&R.

Design: Surveillance study.

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The Survey of Barriers for Vaginal Access Surgery Study.

J Minim Invasive Gynecol

December 2024

Section of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Georgetown University School of Medicine, Washington, DC (Dr. Sokol).

Study Objective: The primary objective of this study was to describe vaginal hysterectomy practice patterns as well as facilitators and inhibitors to performing vaginal hysterectomy among gynecologic surgeons. Secondary objectives were to describe facilitators and inhibitors to the teaching and training of vaginal hysterectomy.

Design: A quantitative analysis of an online survey and qualitative analyses of the one-on-one interviews with gynecologic surgeons were conducted.

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Cortical Tau Aggregation Patterns Associated With Apraxia in Patients With Alzheimer Disease.

Neurology

December 2024

From the Multimodal Neuroimaging Group, Department of Nuclear Medicine (G.N.B., E.J., K.G., A.D.), Department of Psychiatry (F.J.), Department of Neurology (O.A.O., E.K., P.H.W.), Medical Faculty and University Hospital of Cologne, University of Cologne; Molecular Organization of the Brain (G.N.B., A.D.), Institute for Neuroscience and Medicine II, Research Center Juelich; German Center for Neurodegenerative Diseases (F.J.), Bonn/Cologne, Germany; Institute for Translational Research (S.O.B.), and Department of Family Medicine (S.O.B.), Texas College of Osteopathic Medicine, University of North Texas Health Science Center, Fort Worth; and Cognitive Neuroscience (P.H.W.), Institute for Neuroscience and Medicine (INM-3), Research Center Juelich, Germany.

Article Synopsis
  • This study investigated the relationship between tau pathology in specific brain regions and apraxia symptoms in Alzheimer's disease (AD) patients, using PET imaging to assess tau deposition.
  • Researchers hypothesized that certain areas with tau buildup would correlate with the severity of apraxia, a common cognitive dysfunction in AD.
  • Findings revealed significant correlations between tau aggregation in specific praxis-related brain regions and apraxia severity, while no connections were found in primary motor cortex or subcortical regions.
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The American Dream in Oral and Maxillofacial Surgery Residency: A Path Less Taken.

J Oral Maxillofac Surg

December 2024

Division of Oral & Maxillofacial Surgery, Department of Surgery, University of Texas Southwestern Medical Center, Parkland Memorial Hospital, Dallas, TX.

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This report discusses a significant complication following a hysterectomy performed in Mexico on a 46-year-old woman who developed an intra-abdominal abscess due to a retained surgical towel - a severe but rare surgical error. Initially, her post-surgical symptoms, such as abdominal pain, fever, and malaise, were dismissed by her surgeon in Mexico as typical recovery effects. However, as her condition worsened, she sought emergency care in Arizona.

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Post-radiation Angiosarcoma of the Vagina: A Case Report and Literature Review.

Cureus

October 2024

Radiology, Radiology Associates of North Texas, Fort Worth, USA.

Article Synopsis
  • * A unique case was reported of an 83-year-old woman who developed vaginal angiosarcoma 14 years after radiation treatment for rectal cancer.
  • * The patient underwent Taxol chemotherapy and had an impressive response, achieving complete remission four years after the treatment.
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The clinical outcome for children diagnosed with acute lymphoblastic leukemia is a testimony to the success of modern medicine. Over the past few decades, survival has climbed from ∼10% to >90% for certain subgroups. Yet, the outcome for those with relapsed disease is often poor, and survivors struggle with a multitude of healthcare issues, some of which are lifelong.

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We describe the impact of screening on outcomes of patients diagnosed with hepatocellular carcinoma (HCC) in an urban safety-net healthcare system compared to a non-screened cohort diagnosed with HCC. Patients diagnosed with HCC at John Peter Smith Health Network were identified by querying the hospital tumor registry and allocated to the screened cohort if they had undergone any liver imaging within one year prior to HCC diagnosis, while the remainder were allocated to the non-screened cohort. Kaplan-Meier methods and log-rank tests were used to compare 3-year survival curves from an index date of HCC diagnosis.

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Atypical teratoid/rhabdoid tumor (ATRT) is an aggressive, malignant embryonal tumor with dismal long-term survival despite aggressive multimodal therapy. While this tumor typically presents in infancy or early childhood, there are published case reports of adult-onset ATRT. Making prognostic conclusions or therapeutic decisions for this older patient population remains challenging due to the paucity of these reports.

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Background: Alcohol pricing policies can reduce population-level alcohol consumption. To inform these policies, it is essential to understand the price per standard alcoholic drink of the least expensive brands. This study focused on prices of ready-to-drink products because of their accessibility, popularity among young people, and market expansion in recent years.

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Methods for Modeling Early Life Stress in Rodents.

Methods Mol Biol

November 2024

Department of Microbiology, Immunology, and Genetics, University of North Texas Health Science Center, Fort Worth, TX, USA.

Animal models of early life stress/adversity (ELS) have provided a foundation from which our understanding of the psychoneuroimmunology of childhood trauma has expanded over recent decades. Rodent models are a cornerstone of the ELS literature with many studies utilizing paradigms based on early life separation/deprivation protocols and manipulating the cage environment. However, no animal model is perfect.

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Introduction: The Health Equity Scholars Program (HESP) addresses the critical need for a diverse, culturally competent workforce to study and treat older adults from underrepresented populations (URPs) with Alzheimer's disease and related dementias (AD/ADRD). The HESP offers tailored mentored training in AD/ADRD research concepts, aiming to develop successful independent researchers. It recruits Scholars from underrepresented backgrounds as well as those passionate about AD/ADRD health equity research.

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Article Synopsis
  • * A study found that 9.1% of DMD patients also had additional neuromuscular disorders, which can complicate their treatment and data accuracy in clinical trials.
  • * To improve treatment outcomes, it's suggested that expanded genetic testing be done on DMD patients to identify any secondary conditions before they enroll in clinical trials or start treatment.
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A multifactorial lens on risk factors promoting the progression of Alzheimer's disease.

Brain Res

January 2025

Department of Health, Human Performance, and Recreation, Baylor University, Waco, TX, USA. Electronic address:

The prevalence of Alzheimer's disease (AD) among adults has continued to increase over the last two decades, which has sparked a significant increase in research that focuses on the topic of "brain health." While AD is partially determined by a genetic predisposition, there are still numerous pathophysiological factors that require further research. This research requirement stems from the acknowledgment that AD is a multifactorial disease that to date, cannot be prevented.

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Article Synopsis
  • The study looked at how tough childhood experiences, feeling discriminated against, and mental health issues like anxiety and depression are connected for LGBTQ+ adults in the U.S.
  • Researchers surveyed over 4,000 people and found that negative childhood events increased feelings of discrimination, which then led to more anxiety and depression.
  • They believe that these challenges build up over time and suggest that helping kids have better experiences can prevent mental health problems later on.*
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Glioblastoma multiforme (GBM) is the most common type of primary malignant brain tumor and has a dismal overall survival rate. To date, no GBM therapy has yielded successful results in survival for patients beyond baseline surgical resection, radiation, and chemotherapy. Immunotherapy has taken the oncology world by storm in recent years and there has been movement from researchers to implement the immunotherapy revolution into GBM treatment.

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The Infection Control Advocate and Resident Education educational modules integrate and promote infection prevention and control (IPC) measures and residents' rights in nursing homes, targeting long-term care ombudsmen, residents, families, and other resident advocates. Survey respondents (N = 102) reported increased knowledge in understanding IPC and preserving resident rights. Integrating these topics and identifying barriers to promoting IPC is necessary for implementing quality IPC in nursing homes.

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: Diagnosis with a brain tumor is a critical event in the lives of patients and their families due to poor medical prognoses and complex clinical care. Spiritual care interventions have been known to have meaningful effects in morbid diagnoses and palliative medicine, but their role in the neuro-oncologic patient's experience is poorly understood. This systematic review explores the role of spirituality and its relevance to patient care in the diverse setting of brain tumors.

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Recent studies indicate that YouTube has become a primary source of healthcare information for patients. Videos about skin graft procedures on YouTube have accumulated millions of views, yet there lacks a publication investigating the educational quality of this content. With current literature revealing misleading healthcare information found on YouTube, this study aims to evaluate the educational quality of videos related to skin graft procedures.

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