2,533 results match your criteria: "Texas Christian University.[Affiliation]"

is a partially migratory salmonid species, and many migratory populations (known as steelhead) have declined in recent decades in the western United States and Canada. Closely related resident populations (known as rainbow trout) may be an effective resource in the recovery of these declining migratory populations. However, the extent to which different populations of resident rainbow trout produce migratory individuals and how likely these individuals are to return as adults to spawn remains unknown.

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Background: Obesity and inactivity among children are at an all-time high and have been steadily increasing in prevalence over the last thirty years. The school environment provides the ideal setting for reaching a large number of children across diverse populations in order to reverse these trends. However, there are many inconsistent results yielded by school-based physical activity interventions due to implementation length, time for activities, and the use of structured physical activities.

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Paper 5: a methodological overview of methods and interventions.

J Clin Epidemiol

December 2024

RTI International, Research Triangle Park, NC, USA.

Article Synopsis
  • The study evaluated systematic reviews of interventions aimed at improving racial health equity among racialized populations, particularly those published between January 2020 and January 2023.
  • Analysis of 157 reviews revealed that only 14% addressed the role of racism in health disparities, and 67% merely summarized studies without proper synthesis, with many using biased methods for effect sizes.
  • The findings highlight a need for better research quality, comprehensive examination of racism, and a focus on structural interventions to enhance opportunities for racialized groups in addressing health inequities.
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Detecting active sinkholes through combination of morphometric-cluster assessment and deformation precursors.

Sci Total Environ

December 2024

Center for Water Supply Studies, Department of Physical and Environmental Sciences, Texas A&M University-Corpus Christi, 6300 Ocean Drive, Corpus Christi, TX 78412, USA.

Sinkhole hazards pose considerable challenges in the west-central region of Texas. This study integrates multisource datasets and innovative techniques to detect early sinkhole development and identify the processes governing their formation. The techniques employed encompass feature extraction, cluster analysis, and deformation process monitoring.

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Purpose: Regular physical activity is essential for healthy aging. Less than 25% of older U.S.

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Encapsulating CsPbBr quantum dots in silicon nano-sheets not only stabilizes the halide perovskite, but also takes advantage of the nano-sheet for a compatible integration with the traditional silicon semiconductor. Here, we report the preparation of un-passivated CsPbBr ellipsoidal nanocrystals and pseudo-spherical quantum dots in silicon nano-sheets and their enhanced photoluminescence (PL). For a sample with low concentrations of quantum dots in silicon nano-sheets, the emission from CsPbBr pseudo-spherical quantum dots is quenched and is dominated with Pb ion/silicene emission, which is very stable during the whole measurement period.

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Chronic sleep loss alters the inflammatory response and BDNF expression in C57BL/6J mice.

J Neuroimmunol

November 2024

Texas Christian University, Department of Psychology, 2955 South University Drive, Fort Worth, TX 76109, United States of America.

Article Synopsis
  • * A study on mice found that CSR affects inflammatory markers differently in males and females, indicating sex-specific responses to sleep loss.
  • * CSR also reduced hippocampal BDNF expression in males but not in females, highlighting the complex relationship between sleep, inflammation, and sex differences that needs more research.
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Article Synopsis
  • The study looked at how microaggressions (small actions that can hurt people's feelings) and conflicts happen in speech, language, and hearing science training programs.
  • It involved an online survey sent to 236 students, both current and former, from different backgrounds.
  • The results showed that students with marginalized identities experienced more microaggressions, and many cases went unreported, highlighting the need for better support and a more inclusive environment in these programs.
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Objective: Interictal biomarkers are critical for identifying the epileptogenic focus. However, spikes and ripples lack specificity while fast ripples lack sensitivity. These biomarkers propagate from more epileptogenic onset to areas of spread.

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Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy.

J Vis Exp

September 2024

Neuroscience Research Center, Jane and John Justin Institute for Mind Health, Cook Children's Health Care System; Department of Bioengineering, University of Texas at Arlington; Burnett School of Medicine, Texas Christian University;

For children with drug-resistant epilepsy (DRE), seizure freedom relies on the delineation and resection (or ablation/disconnection) of the epileptogenic zone (EZ) while preserving the eloquent brain areas. The development of a reliable and noninvasive localization method that provides clinically useful information for the localization of the EZ is, therefore, crucial to achieving successful surgical outcomes. Electric and magnetic source imaging (ESI and MSI) have been increasingly utilized in the presurgical evaluation of these patients showing promising findings in the delineation of epileptogenic as well as eloquent brain areas.

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The hippocampus (HC) is recognized for its pivotal role in memory-related plasticity and facilitating adaptive behavioral responses to reward shifts. However, the nature of its involvement in the response to reward downshifts remains to be determined. To bridge this knowledge gap, we explored the HC's function through a series of experiments in various tasks involving reward downshifts and using several neural manipulations in rats.

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Spatiotemporal spread of oncolytic virus in a heterogeneous cell population.

Comput Biol Med

December 2024

Department of Physics & Astronomy, Texas Christian University, Fort Worth, TX, USA. Electronic address:

Article Synopsis
  • * Researchers have developed a model using partial differential equations to analyze how viruses can be engineered to limit their spread specifically within tumors.
  • * The study indicates that oncolytic viruses with distinct infection and cell death rates for cancer vs. non-cancerous cells can effectively be contained, highlighting key thresholds that could lead to safer virus variants for cancer treatment.
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Exploring the treatment of SARS-CoV-2 with modified vesicular stomatitis virus.

J Theor Biol

December 2024

Department of Physics & Astronomy, Texas Christian University, Fort Worth, TX, United States. Electronic address:

SARS-CoV-2 caused a global pandemic and is now an endemic virus that will require continued antiviral and vaccine development. A possible new treatment modality was recently suggested that would use vesicular stomatitis virus (VSV) modified to express the ACE2 receptor. Since the modified VSV expresses the cell surface receptor that is used by the SARS-CoV-2 spike protein, the thought is that SARS-CoV-2 virions would bind to the modified VSV and thus be neutralized.

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Exploring the Experience of CRNAs Choosing to Quit Their Jobs: A Qualitative Study.

AANA J

October 2024

Associate Professor in the School of Nurse Anesthesia, Texas Christian University, Fort Worth, Texas. Email:

The purpose of this study was to explore the experience of certified registered nurse anesthetists (CRNAs) choosing to quit their primary place of employment. Interpretative phenomenological analysis is the qualitative framework for this study. Ten CRNAs were interviewed about their experience of quitting their job.

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Frustrative Nonreward: Behavior, Circuits, Neurochemistry, and Disorders.

J Neurosci

October 2024

Section on Synapse Development Plasticity, NIMH/NIH, Bethesda Maryland 20892.

Article Synopsis
  • Frustrative nonreward (FNR) is an emotional response triggered by the lack of essential resources (like food or social interaction), affecting behaviors and physical health.
  • FNR plays a role in various issues like irritability, aggression, motivation disorders, and social behavior, suggesting it’s important for understanding mental health.
  • Recent interest in FNR has increased due to the COVID-19 pandemic, which heightened its effects, leading to more research on animal models and brain mechanisms linked to psychiatric disorders.
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Numerous small molecules have been studied for their ability to counteract oxidative stress, a key contributor to neurodegenerative diseases such as Alzheimer's. Despite these efforts, the pharmacological properties and structure-activity relationships of these compounds remain insufficiently understood, yet they are critical in evaluating a drug molecule's therapeutic potential. A modified tetra-aza macrocycle has demonstrated strong antioxidant activity through various mechanisms; however, its limited permeability presents challenges for advanced formulation studies.

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Redefining at-risk patients undergoiong pancreaticoduodenectomy: Impact of socioeconomic factors including Area Deprivation Index and distance traveled.

Surgery

September 2024

Department of Surgery, Methodist Health System, Dallas, TX; Department of Surgery, Burnett School of Medicine at Texas Christian University, Fort Worth, TX. Electronic address: https://twitter.com/JeyarajahRohan.

Background: The Whipple procedure for pancreatic adenocarcinoma frequently is referred to surgeons at high-volume centers, which requires that patients travel long distances, potentially impacting patient outcomes. Furthermore, patients with pancreatic cancer from underserved areas often have poor outcomes. There are limited data on Whipple outcomes on the basis of both socioeconomic and distance traveled.

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Importance: Nonprofit hospitals are under increasing scrutiny to justify the generous tax benefit they receive due to their tax-exempt status. Quantifying the value of the tax benefit they receive at the federal, state, and local levels is critical for designing informed public health policies and ensuring nonprofit hospitals' taxpayer accountability.

Objective: To estimate the financial benefit that nonprofit hospitals derive from their tax-exempt status and assess how the benefit is distributed across state and local communities.

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Article Synopsis
  • - The study highlights the critical role of home and community-based services (HCBS) for Veterans, particularly in easing the burden on family caregivers, but notes that these services are underutilized despite the resources available through the VA.
  • - Researchers conducted interviews with 23 caregivers of Veterans to identify unmet needs and barriers to accessing HCBS, uncovering themes such as the need for timely information, limited caregiver time (especially during COVID-19), desire for respite, and challenges in the caregiver-patient relationship.
  • - The findings suggest that besides common barriers like service delays and caregiver stress, disagreements between Veterans and their caregivers can hinder access to HCBS, indicating that a comprehensive strategy is needed to improve service utilization.
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Problematic social media use and vaping among Mexican-American college students.

Digit Health

September 2024

Department of Epidemiology, University of Texas Health Science Center at Houston (UTHealth Houston), School of Public Health, Austin, TX, USA.

Introduction: Social media use and vaping nicotine are highly prevalent in the daily lives of young adults, especially among Mexican-American college students. The excessive and compulsive use of social media platforms, coupled with the urge to stay continuously connected, can lead to problematic social media use. To date, no studies have explored the impact of problematic social media use on the daily patterns of vaping among this vulnerable population.

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Confocal laser endomicroscopy (CLE) is a novel technique allowing real time in vivo microscopy during standard endoscopy. Recently, acute mucosal alterations after food administration visualized by CLE have been linked to symptoms in irritable bowel syndrome (IBS). Interestingly, the observed reactions occurred in subjects without demonstrable allergic sensitization to food-this is in line with mechanistic research showing local but not systemic allergic sensitization to foods in an animal model for IBS.

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Youth in the legal system (YILS) report high rates of substance use (SU), complex family/social relationships, and chronic trauma. The current study tested the feasibility of a prevention intervention, Trust-based Relational Intervention® (TBRI®), that leverages family systems by strengthening connection and providing emotional and instrumental guidance and support. TBRI includes the , comprised of Caregiver Training, Youth Training, and joint youth-caregiver Nurture Groups, and .

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[This corrects the article DOI: 10.1007/s40614-024-00404-6.].

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Identification and Treatment of Lung Cancer Oncogenic Drivers in a Diverse Safety Net Setting.

Clin Lung Cancer

August 2024

Department of Internal Medicine (Division of Hematology-Oncology), University of Texas Southwestern Medical Center, Dallas, TX; Harold C. Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address:

Introduction: Advances in the testing and treatment of patients with non-small cell lung cancer (NSCLC) harboring oncogenic drivers have improved outcomes. Little is known about testing and treatment patterns in diverse patient populations.

Methods: We conducted a retrospective study in a diverse cohort of patients treated in the John Peter Smith safety net healthcare system.

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