11,151 results match your criteria: "Texas Tech University Health Sciences Center[Affiliation]"
Immigration Status Checks, Emergency Medicaid Utilization, and Health Care Access for Uninsured Individuals with Kidney Disease.
J Am Soc Nephrol
December 2024
Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Immunoglobulin G4-related pancreatitis presenting as an obstructive pancreatic mass in a Latino male.
J Family Community Med
October 2024
Department of Family Medicine, Texas Tech University Health Sciences Center, Transmountain Campus, El Paso, TX, USA.
Article Synopsis
- IgG4-related disease (IgG4-RD) is an autoimmune condition that can affect various organs, but there is limited research on its occurrence in Latino populations.
- The case report discusses a 40-year-old Latino male diagnosed with IgG4-related pancreatitis, presenting symptoms like diarrhea, jaundice, and elevated liver enzymes.
- After undergoing a biopsy which ruled out cancer, the patient received glucocorticoid therapy that improved his symptoms and liver function, with no negative effects from a COVID-19 infection during treatment.
Characterization of Persister Cells Provides Insights into Mechanisms of Therapy Resistance in Neuroblastoma.
Cancer Discov
December 2024
Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Center, Baylor College of Medicine, Houston, Texas.
Article Synopsis
- The study investigates high-risk neuroblastoma by analyzing primary tumor samples from the same patients at diagnosis and after chemotherapy to find persister cells that survive treatment.
- These persister cells show resistance to chemotherapy through a combination of tumor-intrinsic and tumor-extrinsic mechanisms, which vary based on the tumor's genetic profile.
- Identifying these cells opens up new, personalized treatment approaches aiming to specifically target and inhibit chemoresistance, potentially reducing the chances of disease recurrence.
A Case Report of Fatal Stercoral Colitis: A Possible Complication in Polymyositis.
Int J Rheum Dis
December 2024
Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Rlip76 in ageing and Alzheimer's disease: Focus on oxidative stress and mitochondrial mechanisms.
Ageing Res Rev
January 2025
Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Nutritional Sciences Department, College of Human Sciences, Texas Tech University, Lubbock, TX 79409, United States; Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Department of Neurology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA 5. Department of Public Health, Graduate School of Biomedical Sciences, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Department of Speech, Language, and Hearing Sciences, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address:
Article Synopsis
- * The protein is crucial for various physiological processes, including oxidative stress response and mitochondrial function, and its interaction with Alzheimer's disease proteins suggests a link to neurological health issues like oxidative stress and cognitive decline.
- * Research involving Rlip in animal models of Alzheimer's disease reveals that altering its levels can lead to significant mitochondrial and cognitive impairments, indicating its potential as a therapeutic target in Alzheimer's progression and treatment.
Alpha-Gal Syndrome: A Review for the General Internist.
Am J Med Sci
November 2024
Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
Article Synopsis
- Alpha-gal syndrome is triggered by tick bites, leading to IgE responses against alpha-gal, a carbohydrate present in mammalian meat, causing delayed allergic reactions 2 to 6 hours after eating.
- Symptoms can include skin rashes, gastrointestinal issues, and occasionally severe anaphylaxis, often starting near the previous tick bite site.
- Diagnosis involves monitoring symptom timing and prior tick bite history, with treatment focusing on immediate care during allergic reactions and long-term management requiring a strict meat-free diet.
Cultivating expert thinking skills for experiential pharmacy trainees.
Am J Health Syst Pharm
November 2024
Department of Clinical and Administrative Pharmacy, University of Georgia College of Pharmacy, Albany, GA, and Department of Pharmacology and Toxicology, Medical College of Georgia at Augusta University, Albany, GA, USA.
Article Synopsis
- AJHP is quickly publishing accepted manuscripts online to speed up the publication process.
- These manuscripts have already been peer-reviewed and copyedited but aren't the final version yet.
- The final article will be formatted and proofed by authors before being published later.
Neurocognitive disparities: investigating ethnicity and mental health in rural aging adults.
Aging (Albany NY)
November 2024
Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Article Synopsis
- The study investigated how depression and anxiety affect the relationship between ethnicity and cognitive functioning in rural aging adults, focusing on Hispanic and non-Hispanic White individuals.
- It involved 1,462 participants, revealing that ethnicity significantly influences neurocognitive performance, with Hispanic adults showing lower scores than their non-Hispanic counterparts, even when accounting for anxiety and depression.
- The findings highlight the need for culturally specific interventions to address cognitive impairment in Hispanic aging adults, suggesting that lifetime stressors might contribute to these ethnic disparities in neurocognitive functioning.
Current Burden of Steatotic Liver Disease and Fibrosis among Adults in the United States, 2017-2023.
Clin Mol Hepatol
November 2024
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California, United States.
Article Synopsis
- New terminology for liver diseases, including metabolic dysfunction-associated steatotic liver disease (MASLD) and steatotic liver disease (SLD), has been proposed by experts, prompting a study on their prevalence in the U.S.
- Analysis of data from 12,199 participants in the National Health and Nutrition Examination Survey (2017-2023) revealed that 35% had SLD, with 31.9% specifically classified as MASLD, and a lower prevalence for alcohol-related liver diseases.
- Despite stable overall prevalence of SLD during the COVID-19 pandemic, there was a significant rise in cases of advanced fibrosis, especially in alcohol-related liver disease, which was found to have twice the rate of advanced fibrosis
Transient global amnesia predisposed by rizatriptan and temazepam.
BMJ Case Rep
November 2024
Internal Medicine, Texas Tech University Health Sciences Center School of Medicine Permian Basin, Odessa, Texas, USA.
Article Synopsis
- Transient global amnesia (TGA) is a temporary memory condition often seen in older adults, marked by sudden memory loss that resolves within 24 hours while the person remains aware of their identity.
- A case study of a woman in her 60s illustrates how her acute memory problems were initially mistaken for a stroke after taking migraine and sleep medications, but were later correctly identified as TGA.
- This situation emphasizes the need to carefully distinguish TGA from other serious conditions to avoid unnecessary treatments and hospital costs, particularly since combining certain medications may increase the risk of TGA.
Patent Review of Novel Biologics Targeting Opioid Use Disorder (2018-2024).
ACS Chem Neurosci
December 2024
Department of Pharmaceutical and Biomedical Sciences, Rudolph H. Raabe College of Pharmacy, Ohio Northern University, Ada, Ohio 45810, United States.
Article Synopsis
- In 2023, over 107,000 drug overdose deaths occurred in the U.S., with opioids responsible for approximately 80,000 of these fatalities, primarily due to synthetic opioids like fentanyl.
- New biologics, such as monoclonal antibodies and peptides, are emerging as innovative treatments for opioid overdose and opioid use disorder (OUD) by blocking opioids from affecting the central nervous system and reducing potential for abuse.
- The review highlights recent patents on these biologics and discusses their potential to prevent renarcotization, a risk where overdose patients can relapse into overdosing after being treated with naloxone.
Corrigendum: The concentration of maternal sacubitril/valsartan transferred into human milk is negligible.
Front Public Health
November 2024
Department of Obstetrics and Gynecology, School of Medicine, Texas Tech University Health Sciences Center, Amarillo, TX, United States.
Article Synopsis
- The article discusses the correction of previously published research related to public health.
- This correction addresses specific issues or errors found in the original article.
- It aims to provide accurate information and enhance the reliability of the research findings.
The burden of alcohol and substance use disorders in adolescents and young adults.
Drug Alcohol Depend
January 2025
Division of Gastroenterology and Hepatology, Department of Medicine, University of Arizona College of Medicine, Phoenix, AZ, USA; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Banner University Medical Center, Phoenix, AZ, USA; BIO5 Institute, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA. Electronic address:
Article Synopsis
- * Analysis of Global Burden of Disease Study 2019 data shows a geographical concentration of SUD issues in Europe and the Americas, with males being more affected than females.
- * The research emphasizes the urgent need for effective policies to address the substantial burden of SUDs among AYAs, particularly focusing on alcohol-related harms like injuries and violence.
Acute Toxicity With Lactic Acidosis Associated With Cannabinoid Gummies.
Cureus
October 2024
Internal Medicine/Pulmonary and Critical Care Medicine, Texas Tech University Health Sciences Center, Lubbock, USA.
Article Synopsis
- The use of marijuana and its products is common in the U.S., but they can lead to serious health issues, including toxic reactions from edible forms with uncertain dosages.
- A case report detailed a patient who consumed too many cannabinoid gummies, leading to symptoms like lethargy, agitation, vomiting, high heart rate, high blood pressure, and respiratory failure.
- The patient received supportive care in the ICU, and it’s important for doctors to consider cannabis toxicity as a potential cause of symptoms like lactic acidosis when patients show these signs in the emergency room.
Vaccine value profile for schistosomiasis.
Vaccine
July 2024
World Health Organization, Geneva, Switzerland.
Article Synopsis
- * In 2019, approximately 236.6 million people required treatment for schistosomiasis, highlighting its significant impact on fishing and agricultural communities.
- * The Vaccine Value Profile (VVP) is a comprehensive assessment created by a group of experts to evaluate the public health and economic potential of new vaccines targeting schistosomiasis, emphasizing the need to address existing research gaps.
Measuring the effects of ketogenic diet on neuropsychiatric disorder: A scoping review.
Prog Neuropsychopharmacol Biol Psychiatry
November 2024
Psychiatry Department, Texas Tech University Health Sciences Center, 3601 4th Street STOP 8103, Lubbock, TX 79430-8103, USA. Electronic address:
Article Synopsis
- The scoping review investigates the ketogenic diet's potential effectiveness as a treatment for various neuropsychiatric disorders, noting that while there is interest, the overall effectiveness is still uncertain.
- It considers a range of study types, including randomized controlled trials and observational studies, that follow DSM-5 guidelines for neuropsychiatric conditions.
- The review analyzes 30 studies that suggest the ketogenic diet could improve symptoms in disorders like Autism, ADHD, depression, and anxiety, but highlights the need for more thorough research to validate its use as a standard treatment.
Curcumin Mitigates Muscle Atrophy Potentially by Attenuating Calcium Signaling and Inflammation in a Spinal Nerve Ligation Model.
Curr Issues Mol Biol
November 2024
Department of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX 79406, USA.
Denervation-induced calcium/calmodulin-dependent protein kinase II (CaMKII) activation and inflammation can result in muscle atrophy. Curcumin and bisdemethoxycurcumin are well known to exhibit an anti-inflammatory effect. In addition, curcumin has been shown to attenuate CaMKII activation in neuronal cells.
View Article and Find Full Text PDFThe Effect of Geranylgeraniol and Ginger on Satellite Cells Myogenic State in Type 2 Diabetic Rats.
Curr Issues Mol Biol
October 2024
Department of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX 79406, USA.
Type 2 diabetes (T2D) is associated with increased inflammation and reactive oxygen species (ROS) in muscles, leading to basal satellite cell (SC) myogenic impairment (i.e., reduction in SC pool), which is critical for maintaining skeletal muscle mass.
View Article and Find Full Text PDFSeasonal Patterns in Eosinophilic Esophagitis-Related Emergency Department Visits: A National Database Analysis.
Am J Gastroenterol
November 2024
Department of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, USA .
Introduction: This study investigates seasonal variations in eosinophilic esophagitis (EoE)-related emergency department visits among adults.
Methods: We analyzed the National Emergency Department Sample (2016-2021), identifying adult patients with EoE using ICD-10 codes. Generalized additive models assessed seasonal patterns.
Alcohol-related liver and extrahepatic malignancies: burden of disease and socioeconomic disparities in 2019.
Eur J Gastroenterol Hepatol
February 2025
Division of Gastroenterology and Hepatology, Department of Medicine, University of Arizona College of Medicine.
Background: Alcohol is linked to various cancers. While many studies have focused on developed countries, the burden of alcohol-related cancers in developing countries remains underexplored.
Methods: We analyzed data from the Global Burden of Disease Study (2000-2019) to assess mortality and disability-adjusted life years (DALYs) from alcohol-related cancers in low and low-to-middle sociodemographic index (SDI) countries.
A holistic approach to sustain and support lifelong practices of wellness among healthcare professionals: generating preliminary solid steps towards a culture of wellness.
BMC Med Educ
November 2024
Department of Pediatrics, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA.
Background: The COVID-19 pandemic has served as a catalyst for recognizing the challenging environments in which healthcare workers operate, underscoring the urgent need to enhance their wellness to better support themselves and others. The implementation of a culture of wellness within the context of healthcare education, with a particular emphasis on individual-level strategies, allows for the realization of its intrinsic value and significance as a foundation for broader organizational strategies. This approach facilitates the establishment of a sustainable culture of wellness that benefits both current and subsequent generations of healthcare professionals.
View Article and Find Full Text PDFAnalysis of Medicare reimbursement trends for procedures in allergy and immunology between 2013 and 2022.
Ann Allergy Asthma Immunol
November 2024
Allergy and Immunology Division, Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas.
Background: Cosmetically unappealing temporal volume loss can develop as a result of facial aging.
Objective: To present an evidenced-based approach towards safe and effective temple filling.
Methods: We review the underlying anatomy of the temple and optimal anatomy-driven injection techniques associated with temple volumization.
Granulomatous Reactions From Microneedling: A Systematic Review of the Literature.
Dermatol Surg
November 2024
Meridian Dermatology, Meridian, Idaho.
Article Synopsis
- Microneedling is a popular and minimally invasive skin rejuvenation technique, but rare granulomatous reactions have been documented following the procedure.
- This study systematically reviewed existing literature and identified 13 studies involving 15 patients aged 26-74 who experienced non-necrotizing granulomatous inflammation post-procedure, often linked to motorized microneedling and Vitamin C use.
- Treatment options varied and had inconsistent success, with no clear standard approach, highlighting that these reactions can be difficult to manage.
Safety of Non-vitamin K Antagonist Oral Anticoagulants on Outcomes After Transcatheter Aortic Valve Replacement: An Updated Meta-Analysis.
Cureus
October 2024
Department of Internal Medicine, The University of Texas Rio Grande Valley, Edinburg, USA.
The existing evidence on the use of non-vitamin K oral anticoagulants (NOACs) after transcatheter aortic valve replacement (TAVR) surgery is inconclusive and contradictory. Likewise, major society guidelines remain ambivalent about NOAC use around the time of TAVR. The objective of our meta-analysis was to assess the efficacy of NOACs in comparison to vitamin K antagonists (VKAs) in lowering complications following TAVR.
View Article and Find Full Text PDF