33,782 results match your criteria: "Tex; Texas A&M University College of Medicine[Affiliation]"
Prediction of Ischemic Stroke Functional Outcomes from Acute-Phase Noncontrast CT and Clinical Information.
Radiology
October 2024
From the Departments of Radiology (Y.L., J.O., B.J., S.O., Y. Yang, M.E.M., J.J.H., G.Z.) and Neurology (M.L., G.A.), Stanford University School of Medicine, 1201 Welch Rd, Stanford, CA 94305-5488; Department of Radiology, University of California-San Francisco, San Francisco, Calif (Y. Yu); Department of Electrical Engineering (J.O.) and Department of Environmental Health and Safety (J.W.), Stanford University, Stanford, Calif; Henry M. Gunn Senior High School, Palo Alto, Calif (S.L.L.); National Heart and Lung Institute, Imperial College London, London, UK (G.Y.); Neurology Service, Department of Clinical Neurosciences, Lausanne University Hospital and University of Lausanne, Switzerland (P.M.); Department of Neurology, University of California Los Angeles, Los Angeles, Calif (D.S.L.); and Department of Neuroradiology, University of Texas MD Anderson Cancer Center, Houston, Tex (M.W.).
Article Synopsis
- The study aims to improve prediction of 90-day functional outcomes in ischemic stroke patients using a deep learning model that combines non-contrast CT images and clinical data, potentially aiding healthcare planning and clinical trials.
- The dataset included 1,335 patients from multiple trials and registries, and the model demonstrated superior accuracy in predicting outcomes compared to models using only imaging or clinical data alone.
- The fused model achieved a mean absolute error (MAE) of 0.94 for mRS score prediction and an AUC of 0.91 for identifying unfavorable outcomes, indicating it significantly outperforms existing methods.
TRENDING CULTURAL DRIVERS OF SMOKELESS TOBACCO: FOR RECENT REFUGEE AND IMMIGRANTS AS KNOWLEDGE, ATTITUDES, AND BEHAVIOR DETERMINANTS: A SOUTH TEXAS ORAL HEALTH NETWORK COLLABORATIVE STUDY.
Tex Dent J
April 2024
The University of Texas Health Science Center at San Antonio, School of Dentistry, Department of Periodontics, San Antonio, Texas.
Objectives: Smokeless tobacco (SLT) use is a phenomenon that is detrimental to the health of adults worldwide and dramatically impacts the health of resettled populations. The prevalence of SLT has exponentially grown as a public health threat for the refugee and immigrant populations and is worthy of addressing. This research study examined the SLT cultural drivers of the Texas immigrant and refugee community, which led to their knowledge, perception, awareness, and cessation practices.
View Article and Find Full Text PDFEstablish a novel immune-related gene prognostic risk index (IRGPRI) associated with CD8+ cytotoxic T lymphocytes in non-small-cell lung cancer (NSCLC).
Heliyon
October 2024
Department of Medical Administration, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Background: The aim of this study is to create an index called IRGPRI (immune-related gene prognostic risk index) that can be utilized for predicting the prognosis and assessing the efficacy of immune checkpoint inhibitors (ICIs) therapy in patients with non-small-cell lung cancer (NSCLC).
Methods: Distinguishing gene expression patterns (DEGs) were detected in CD8 cytotoxic T lymphocytes (CTLs) compared to other cellular types such as CD4 T cells, B cells, plasma cells, and CD8 Tex using the advanced technology of Single-cell RNA Sequencing (scRNA-seq). The construction of IRGPRI was accomplished by employing LASSO Cox regression analysis.
Comparison of Neighborhood Disadvantage Indices on Emergency Medical Services Interventions and Outcomes for Pediatric Out-of-Hospital Emergencies.
Acad Pediatr
October 2024
Division of Emergency Medicine (S Ramgopal, S Kemal, M Attridge, and M Macy), Ann and Robert H. Lurie Children's Hospital of Chicago, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Ill; Stanley Manne Children's Research Institute (S Ramgopal, S Kemal, M Attridge, and M Macy), Chicago, Ill.
Objective: Measures of neighborhood disadvantage demonstrate correlations to health outcomes in children. We compared differing indices of neighborhood disadvantage with emergency medical services (EMS) interventions in children.
Methods: We performed a retrospective study of EMS encounters for children (<18 years) from approximately 2000 US EMS agencies between 2021 and 2022.
Soluble mesothelin-related peptide as a prognosticator in pleural mesothelioma patients receiving checkpoint immunotherapy.
J Thorac Cardiovasc Surg
October 2024
Systems Onco-Immunology Laboratory, David J. Sugarbaker Division of Thoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Tex; Division of Hemato-Oncology, Department of Medicine, Baylor College of Medicine, Houston, Tex; David J. Sugarbaker Division of Thoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Tex. Electronic address:
Article Synopsis
- Immune checkpoint therapy (ICT) has changed the treatment landscape for malignant pleural mesothelioma (MPM), but nearly half of patients do not see benefits, emphasizing the need for predictive biomarkers.
- This study evaluated the prognostic value of serum soluble mesothelin-related peptide (SMRP) and PD-L1 levels in 125 MPM patients undergoing ICT, using statistical analyses to determine their impact on overall survival (OS).
- Results showed that higher pre-ICT SMRP levels are linked to poorer prognosis, with low levels indicating better survival outcomes, suggesting that SMRP could serve as a valuable biomarker for future MPM treatment studies.
Initial patient characteristics of Thoracic Surgical Oncology Group 102: A multicenter prospective registry of active surveillance in patients with multiple ground-glass opacities.
J Thorac Cardiovasc Surg
October 2024
Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Article Synopsis
- The study investigated the feasibility and safety of active surveillance for patients with multiple ground glass opacities (GGOs) in the lungs, which are a common concern in medical imaging.
- A total of 337 patients, primarily older adults with a significant history of smoking, were enrolled and monitored over time, with each GGO documented via CT scans every 6 to 12 months.
- Preliminary findings suggest that active surveillance is a viable management option for patients, with ongoing assessments planned to evaluate long-term safety and outcomes over five years.
Surgeon preferences for self-treatment in locally advanced non-small cell lung cancer: Would we practice what we preach?
J Thorac Cardiovasc Surg
October 2024
Division of Thoracic Surgery, Mayo Clinic, Rochester, Minn.
Extracting and characterizing of a new vegetable lignocellulosic fiber produced from C. humilis palm trunk for renewable and sustainable applications.
Int J Biol Macromol
November 2024
Chemical Engineering Department, College of Engineering, University of Ha'il, PO Box 2440, Ha'il 81441, Saudi Arabia; Chemical Engineering Department, Faculty of Engineering, University of Blida, PO Box 270, Blida 09000, Algeria.
Article Synopsis
- Research on natural fibers has increased due to the demand for sustainable materials, focusing on Chamaerops humilis trunk (ChT) as a potential alternative to synthetic fibers.
- The study involves a comprehensive examination of ChT fibers' characteristics using various techniques like density measurement, moisture content analysis, X-ray diffraction, and tensile testing.
- Findings reveal that ChT fibers have favorable properties such as a density of 0.97 g/cm and heat resistance up to 225 °C, making them promising for use in biocomposites and textile applications.
Commentary: Cutting through the noise: Can natural language processing improve literature review in cardiac surgery?
J Thorac Cardiovasc Surg
October 2024
Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Tex; Division of General Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Tex; Department of Cardiovascular Surgery, Texas Heart Institute, Houston, Tex. Electronic address:
A Meta-analysis Comparing Deep Inferior Epigastric Perforator Flaps and Latissimus Dorsi Flaps in Breast Reconstruction.
Plast Reconstr Surg Glob Open
October 2024
Institute for Reconstructive Surgery, Houston Methodist Hospital, Weill Cornell Medical College, Houston, Tex.
Article Synopsis
- - This meta-analysis compares two breast reconstruction techniques, Deep Inferior Epigastric Perforator (DIEP) flaps and Latissimus Dorsi (LD) flaps, to evaluate patient satisfaction and complication rates to help guide clinical decisions.
- - The analysis included 13 studies with a total of 2,128 patients, showing that DIEP flaps resulted in higher breast satisfaction and physical well-being scores, while also having lower seroma incidence compared to LD flaps.
- - Although DIEP flaps were associated with increased risk of complications such as skin flap necrosis and wound dehiscence, they overall provided better patient satisfaction outcomes than LD flaps.
The influence of the American Association for Thoracic Surgery on clinical trial development by cardiothoracic surgeons.
J Thorac Cardiovasc Surg
October 2024
Division of Cardiac Surgery, Department of Cardiovascular and Thoracic Surgery, West Virginia University School of Medicine, Morgantown, WVa. Electronic address:
Objective: Clinical trials play a critical role in the rapidly evolving field of cardiothoracic surgery and the American Association for Thoracic Surgery Clinical Trials Methods Course has provided a biannual symposium led by preeminent surgeons with vast experience in planning, conducting, and analyzing surgical clinical trials. This study hypothesizes that participation in the course is associated with future success in clinical trial leadership.
Methods: A list of course attendees (2014-2022) was queried in ClinicalTrials.
Strategic implementation of a new robotic mitral repair program: Early experience and outcomes.
J Thorac Cardiovasc Surg
October 2024
Division of Cardiovascular Surgery, Department of Surgery, Hospital of the University of Pennsylvania, University of Pennsylvania, Philadelphia, Pa. Electronic address:
Article Synopsis
- The report discusses the low adoption of robotic mitral repair procedures and outlines the authors' early experiences in successfully launching such a program.
- The strategy involved educating the team, hands-on practice, gradual progression, and careful patient selection, along with regular analysis and feedback.
- Results showed that from March 2022 to February 2024, 50 patients underwent the procedure with a 98% success rate, no deaths, and minimal issues post-surgery, suggesting that the outlined approach is effective for similar programs.
Peak nasal inspiratory flow assessment of polyp size and response from SYNAPSE.
J Allergy Clin Immunol Glob
November 2024
Catholic University of Leuven, Leuven, Belgium.
Article Synopsis
- The SYNAPSE study found that mepolizumab, when combined with standard care, significantly reduced nasal polyp scores in patients suffering from chronic rhinosinusitis with nasal polyps compared to placebo.
- Researchers aimed to examine the connection between nasal polyp scores, peak nasal inspiratory flow, and patient-reported outcomes.
- Results indicated that patients who showed improvements in nasal polyp scores also experienced better peak nasal flow and symptom relief compared to those who did not improve.
The QIBA Profile for Diffusion-Weighted MRI: Apparent Diffusion Coefficient as a Quantitative Imaging Biomarker.
Radiology
October 2024
From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).
Article Synopsis
- The Apparent Diffusion Coefficient (ADC) measures how water moves in tissues, helping doctors see changes caused by diseases or treatments.
- The QIBA has made progress on using ADC measurements in different body parts like the brain, liver, prostate, and breast, by creating guidelines for their use.
- The report explains the right amounts of change in ADC values that indicate real differences in tissue, helping doctors track patients’ health more accurately.
Nanomechanical and bending properties of nickel-titanium orthodontics archwires by depth-sensing indentation.
Am J Orthod Dentofacial Orthop
January 2025
Departments of Materials Science and Engineering and Bioengineering, University of Texas at Dallas, Richardson, Tex.
Introduction: This study aimed to identify the link between alloy microstructures and the nanomechanical properties of different orthodontic archwires containing nickel-titanium (NiTi) by sensing sliced areas. Previous studies have focused on analyzing and contrasting physical properties such as microhardness, elasticity modulus, and resistance; therefore, the trend is to consider microstructural characteristics in detail.
Methods: Thirty archwire samples from 3 different commercial brands, American Orthodontics (AO), 3M Unitek (3M), and Borgatta, were analyzed through scanning electron microscopy and energy-dispersive x-ray spectroscopy, transmission electron microscopy, atomic force microscopy, Berkovich nanoindentation, and microtensile microscopy to determine their chemical-crystallographic characteristics and nanomechanical and bending characteristics.
CD8 T cell exhaustion and its regulatory mechanisms in the tumor microenvironment: key to the success of immunotherapy.
Front Immunol
October 2024
Department of General Surgery, Clinical Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
A steady dysfunctional state caused by chronic antigen stimulation in the tumor microenvironment (TME) is known as CD8 T cell exhaustion. Exhausted-like CD8 T cells (CD8 Tex) displayed decreased effector and proliferative capabilities, elevated co-inhibitory receptor generation, decreased cytotoxicity, and changes in metabolism and transcription. TME induces T cell exhaustion through long-term antigen stimulation, upregulation of immune checkpoints, recruitment of immunosuppressive cells, and secretion of immunosuppressive cytokines.
View Article and Find Full Text PDFMisconceptions and Facts About Orthostatic Hypotension.
Am J Med
October 2024
Beth Israel Deaconess Medical Center, Harvard Medical School, Department of Medicine, Division of General Medicine, Boston, Mass.
Article Synopsis
- Orthostatic hypotension is when your blood pressure drops a lot when you stand up, making you feel dizzy or weak.
- It can cause falls and other serious health problems but many people don’t know they have it because they don't always feel symptoms.
- There are also common misunderstandings about this condition that make it harder to recognize and treat.
Opportunities for using artificial intelligence in air pollution and health research.
J Allergy Clin Immunol
January 2025
Department of Population Health, Dell Medical School, University of Texas at Austin, Austin, Tex.
Understanding Patient Satisfaction: A Comparative Analysis of Telemedicine versus In-person Encounters in Pediatric Plastic Surgery.
Plast Reconstr Surg Glob Open
October 2024
From the Division of Plastic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Tex.
Background: Telemedicine services experienced unprecedented growth during the coronavirus 2019 pandemic, offering patients remote access to care while minimizing exposures to possible infection. Our institution has one of the country's largest pediatric plastic surgery divisions and serves both a prominent metro area and sprawling rural community. Given the increasing utilization of telemedicine across several surgical subspecialties, this study aims to evaluate patient satisfaction following pediatric plastic surgery telemedicine encounters.
View Article and Find Full Text PDFThe Controversy over Price Transparency: Patients and Plastic Surgeons Disagree.
Plast Reconstr Surg Glob Open
October 2024
Institute of Dermatology and Plastic Surgery, Cleveland Clinic Foundation, Cleveland, Ohio.
Background: The No Surprises Act (NSA) went into effect on January 1, 2022. This federal law is designed to minimize surprise bills for emergency care, out of network (OON) care, and care for uninsured or self-pay individuals. To achieve these goals, the NSA relies heavily on physicians providing cost estimates to patients prior to administering care.
View Article and Find Full Text PDFImplications of the initial braidwood v. Becerra ruling for colorectal cancer outcomes: a modeling study.
J Natl Cancer Inst
October 2024
Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands.
Article Synopsis
- The Affordable Care Act removed out-of-pocket costs for recommended preventive services, but a recent court ruling may reinstate these costs for over 150 million Americans, particularly affecting colorectal cancer screenings.
- If the court's decision stands, it could specifically impact screening for colorectal cancer in people aged 45-49 and polyp removals during colonoscopies for all ages.
- A simulation showed that a decrease in screening participation by 8% could lead to a significant rise in colorectal cancer cases and deaths, while potentially reducing costs in the short term due to increased cost-sharing, but higher participation loss could result in greater overall healthcare costs.
Successful diaphragm repair following radiofrequency ablation for renal cell carcinoma: A case report.
Int J Surg Case Rep
November 2024
Department of Thoracic and Cardiovascular Surgery, Chungnam National University Hospital, Republic of Korea. Electronic address:
Introduction And Importance: This study aimed to assess the effectiveness of surgical intervention in treating traumatic diaphragmatic rupture accompanied by pleural empyema resulting from radiofrequency ablation for renal cell carcinoma.
Case Presentation: A 72-year-old female patient underwent radiofrequency ablation at our institution's urology department to address a 4-cm tumor in the left upper kidney detected during routine health screening. Subsequently, the patient experienced persistent fever from the 5th day post- procedure.
Molecular Markers in the World Health Organization Classification of Head and Neck Tumors, Fifth Edition.
Radiographics
October 2024
From the Departments of Radiology (A.A., A.B., J.M., D.R., P.R.) and Neuroradiology (P.V.), Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224; Department of Radiology, Mayo Clinic, Rochester, Minn (G.B.); and Department of Radiology, UT Southwestern Medical Center, Dallas, Tex (K.V.).
The past decade has seen exponential advancements in molecular markers and the genetics of tumors, recognizing the limitations of conventional histopathology for grading, classification, and prognostication. Such advances have resulted in changes to classification systems, for example, with the incorporation of objective molecular and genetic information into the 2021 World Health Organization (WHO) classification of central nervous system tumors. The fifth edition of the WHO classification of head and neck tumors (HN5) (beta online version, 2022) also introduced major changes based on molecular markers, including additions, deletions, and reclassifications of entities, with the idea of being more objective and standardized.
View Article and Find Full Text PDFImmunosuppressive tumor microenvironment in gastric signet-ring cell carcinoma.
World J Clin Oncol
September 2024
Center for Basic and Translational Research, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
Article Synopsis
- Gastric signet-ring cell carcinoma (GSRCC) is a unique and aggressive form of stomach cancer that is often resistant to traditional treatments like chemotherapy and radiotherapy, particularly in advanced stages.
- Recent research using advanced techniques like single-cell RNA sequencing has uncovered a highly immunosuppressive tumor microenvironment (TME) in GSRCC, which contributes to immune escape and poor patient outcomes.
- The altered immune cell composition, characterized by a rise in follicular B cells and a decline in functional T and B cells, may play a crucial role in the poor prognosis of GSRCC, highlighting the need for improved immunotherapy approaches.
Surgical Repair of Postinfarction Left Ventricular Pseudoaneurysm.
Tex Heart Inst J
October 2024
Department of Cardiovascular and Thoracic Surgery, Jeonbuk National University Hospital, Jeonbuk National University College of Medicine, Jeonju-si, Republic of Korea.
Left ventricular pseudoaneurysm is a serious and rare disorder that usually develops after acute myocardial infarction. It can lead to potentially lethal mechanical complications, such as acute left ventricular free wall rupture. This report presents the case of a 64-year-old man with a left ventricular pseudoaneurysm and myocardial rupture that was managed by left ventricular restoration with aneurysmectomy and coronary artery bypass with 2 grafts.
View Article and Find Full Text PDF