2,440 results match your criteria: "Tepecik Research and Training Hospital; İzmir-Turkey. kilicaslanbaris@yahoo.com.[Affiliation]"

Introduction And Hypothesis: This study was aimed at exploring the immediate impacts of pelvic floor muscle exercises (PFMEs) on various maternal physiological parameters in pregnant women.

Methods: The study included a total of 52 women, 26 pregnant (Pregnant group: 28.04±6.

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Background: Obesity is known as a risk factor for endometrial cancer (EC). Only a few studies investigate the relationship between sarcopenia and sarcopenic obesity and EC. In this study, our aim was to investigate the relationship between the cross-sectional imaging-based body composition parameters and the disease prognosis in low-grade (LG) and high-grade (HG) EC.

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Background & Aims: Prognostic factors of metastatic rectal cancer are not well known. We aim to determine prognostic factors affecting survival for metastatic rectal cancer patients and also to investigate the effect of tumor localization on overall survival.

Methods: Metastatic rectal cancer patients who received treatment in 5 different centers between 2012 and 2022 were included.

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Corneal sensitivity and ocular surface health in patients undergoing femtosecond LASIK retreatment for residual refraction.

J Cataract Refract Surg

November 2024

From the Department of Ophthalmology, Ekol Eye Hospital, Izmir, Turkey (Cinar); İzmir Tepecik Training and Research Hospital Ophthalmology Clinic, University of Health Sciences, Izmir, Turkey (Yuce); Department of Ophthalmology, Alaattin Keykubat University, Alanya, Antalya, Turkey (Aslan).

Purpose: To assess corneal sensitivity and the ocular surface in patients undergoing primary femtosecond laser in situ keratomileusis (FS-LASIK) and those undergoing FS-LASIK retreatment under the same flap due to residual refractive error.

Setting: Ekol Eye Hospital, Izmir, Turkey.

Design: Prospective case series.

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Aim: The aim of this study was to compare the differences between angles of bladder neck in girls with overactive bladder and those in healthy ones using transabdominal ultrasonography.

Materials And Methods: This study consists of 28 girls complicated with overactive bladder (Group I) and 40 healthy girls (Group II). The anteroposterior vesical wall angle (APVA), urethroposterior vesical wall angle (UPVA), urethroanterior vesical wall angle (UAVA), thickness of bladder mucosa, distance of urethral orifices, and distance between ureter and urethra orifice were measured in supine position using transabdominal ultrasonography.

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Article Synopsis
  • This study evaluates the clinical features and outcomes of acute cannabis toxicity versus acute synthetic cannabinoid receptor agonist toxicity in European emergency departments from 2013-2020.
  • Using data from the European Drug Emergencies Network Plus, researchers analyzed 2,657 cases of cannabis exposure and 503 cases of synthetic cannabinoid exposure to compare their effects.
  • The findings indicate that synthetic cannabinoid exposures are linked to more severe neuropsychiatric symptoms, while cannabis exposures are associated with cardiovascular issues.
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Unlabelled: Rituximab (RTX) is a chimeric monoclonal antibody that targets the CD20 antigen on B cells and is used in various autoimmune disorders. In this study, we aimed to measure the awareness of pediatric rheumatologists about the use of RTX through a survey. Between February and March 2023, a 42-question survey was sent via email to pediatric rheumatology specialists in Turkey.

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Article Synopsis
  • - The study analyzed data from a randomized trial in Türkiye involving 1,266 volunteers aged 18-55 to assess how previous COVID-19 infections affected adverse events after receiving the TURKOVAC vaccine compared to CoronaVac.
  • - Among participants, 27.7% had a history of COVID-19, with local and systemic adverse events (AEs) occurring in 37.3% and 39% of individuals, respectively, and slightly higher rates were noted shortly after vaccination.
  • - Following the second dose, 1,203 participants were evaluated, showing similar rates of local and systemic AEs for those with and without prior COVID-19 infection, with both TURKOVAC and CoronaVac exhibiting comparable
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Biomarkers such as hormone receptors (HR) and human epidermal growth factor receptor2 (HER2) may change after neoadjuvant chemotherapy (NAC) in breast cancer patients. The aim of this study was to investigate the rates of receptor change after NAC and to evaluate the prognostic impact of change. Patients with breast cancer who received NAC were included in the study.

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Article Synopsis
  • Vaccines have significantly reduced COVID-19 hospitalizations among adolescents in Turkey, evidenced by a decline in hospitalizations during the vaccination period compared to pre-vaccination.
  • The study revealed that while there were more total hospitalizations during the vaccination period, the proportion of vaccinated adolescents requiring hospitalization was lower, reflecting the effectiveness of the vaccine.
  • Additionally, breakthrough infections in vaccinated adolescents were generally milder and less severe compared to infections in unvaccinated peers, with many being asymptomatic.
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Factors influencing mortality in COVID-19-associated mucormycosis: The international ID-IRI study.

Med Mycol

July 2024

Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Gulhane School of Medicine, Ankara, Turkey.

Article Synopsis
  • - The COVID-19 pandemic led to a rise in cases of mucormycosis, particularly in India, prompting a study to analyze factors affecting mortality in COVID-19-associated mucormycosis (CAM) among patients in mainly Asian and some African countries.
  • - The study included 162 CAM patients, primarily older males, with a high prevalence of diabetes and rhino-orbital-cerebral mucormycosis; results indicated a 39% mortality rate influenced by advanced age, use of rituximab, and diabetic ketoacidosis as significant risk factors.
  • - Findings suggest that surgical debridement improves survival rates, and combining antifungal treatments with surgery significantly enhances outcomes for CAM patients.
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A scoping review of pain resulting from the endotracheal suctioning of paediatric intensive care patients.

Int J Palliat Nurs

June 2024

Information and Document Management, İzmir Kâtip Çelebi University, Faculty of Social Sciences and Humanities, İzmir, Turkey.

Background: This scoping review was conducted to summarise and map studies on pain resulting from endotracheal suctioning in paediatric intensive care patients.

Method: This scoping review conducted in June 2022 was performed by screening articles published in English. Scopus, PubMed, Cochrane, Web of Science, MedLine and Ovid databases were used for screening.

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Introduction: Anti-rods and rings (anti-RR) antibodies have recently been described as a cytoplasmic pattern in IIF-based screening of autoantibodies on HEp-2 cells and ICAP has named it as AC-23. It is most frequently related to drug-induced antibody generation. This study aimed to investigate the clinical significance of AC-23 positivity and its relevance to the diagnosis and/or follow-up of the associated diseases and/or drug use.

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Chanarin-Dorfman syndrome (CDS) is a multisystem autosomal recessive disorder due to variants of the ABHD5 gene, characterized by lipid vacuoles in the liver and leukocytes, and possible involvement of eyes, ears, skeletal muscle, and central nervous system. CDS may present with skin changes, most commonly congenital non- bullous ichthyosiform erythroderma, however erythrokeratoderma-like findings have been rarely reported in CDS patients. Herein, we report clinical, histopathological and genetic findings of four patients with CDS presenting with different clinical forms of erythrokeratoderma (three with progressive symmetric erythrokeratoderma-like features and one with erythrokeratoderma variabilis (EKV)-like features), including one patient with a novel mutation in ABHD5.

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In the fight against the COVID-19 pandemic, the importance of health literacy in individuals' attitudes has increased. This study aimed to show whether there is a relationship between health literacy and adherence to personal protective anti-COVID-19 health behaviors in health workers and their relatives and to evaluate the barriers to adherence to personal protective anti-COVID-19 health behaviors. Designed as a cross-sectional mixed-methods study.

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Background: Endometrioid carcinoma, originating in the endometrium glandular cells, is often detected early and treated by surgery. However, post-treatment life quality remains poorly studied, explicitly focusing on sleep quality, fatigue, and depression.

Methods: In this cross-sectional, observational study, 147 female patients with endometrioid-type endometrial carcinoma were evaluated using standardised tools-Pittsburgh Sleep Quality Index (PSQI), Fatigue Assessment Scale (FAS), and Beck Depression Inventory (BDI).

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Article Synopsis
  • - The study focused on distinguishing tuberculous lymphadenitis (TBLN) from non-tuberculous lymphadenitis (NTBLN) in adults in Turkiye, analyzing demographic, clinical, and laboratory data from patients with swollen lymph nodes.
  • - A total of 812 patients were studied, revealing that TBLN was the most common diagnosis (53.69%), with higher occurrence in females and those who had elevated erythrocyte sedimentation rate and positive test results for tuberculosis (p < 0.05).
  • - The findings suggest that identifying specific variables can help clinicians improve their diagnosis and treatment strategies for adult lymphadenopathy.
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Objectives: The study aimed to improve family caregivers' skills and evaluate the effect on their anxiety levels.

Method: In our study, family caregivers of patients unable to perform daily activities were provided with care training. Their anxiety levels were examined before and after the training.

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Introduction: Nongoitrous congenital hypothyroidism-6 (CHNG6) is a thyroid hormone resistance syndrome caused by a thyroid hormone receptor alpha () gene mutation, characterized by tissue-specific hypothyroidism and near-normal thyroid function tests. Snijders Blok-Campeau syndrome (SNIBCPS) is a rare autosomal dominant neurodevelopmental disorder caused by mutations in genes, characterized by intellectual retardation, hypotonia, speech problems, and distinctive facial findings.

Case Presentation: We report a 3-year-old dual phenotype Turkish girl with novel variants both in the and genes, presenting with developmental delay, hypotonia, and congenital hypothyroidism.

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Article Synopsis
  • The study aimed to evaluate the effects of adjuvant treatments and factors affecting recurrence and survival in patients with stage IIB endometrial cancer, using data from surgeries performed in Turkey between 2005 and 2022.
  • Out of 7323 patients, 565 were identified as stage IIB; most received adjuvant radiotherapy, but the study found no significant survival benefits from adjuvant treatments overall.
  • Notably, patients with tumors larger than 4 cm and myometrial invasion greater than 50% had higher recurrence rates, while adjuvant treatment improved overall survival only for those with deep myometrial invasion.
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Objective: The purpose of the study was to analyse the role of prognostic factors on the risk of recurrence and overall survival of patients with uterine adenosarcoma.

Methods: A retrospective international multicentre study involving 46 centres collected 32 cases of uterine adenosarcoma, and these cases were included in the present subanalysis. Clinical and demographic features and tumour characteristics were gathered, as well as information on treatment and relapse.

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Purpose: To compare the efficacy, safety and advantages of the total tubeless (TT) percutaneous nephrolithotomy (PCNL) and standard PCNL in the supine position.

Methods: This study was carried out at İzmir Tepecik Health Application and Research Center. A total of 87 patients were examined.

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Purpose: Fetal growth restriction (FGR) is a common pregnancy complication that can be associated with several adverse perinatal outcomes. One of these negative outcomes is ductus arteriosus, especially in preterm babies. In this study, intrauterine heart function and ductus diameter were evaluated in babies with FGR.

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