2,439 results match your criteria: "Tepecik Research and Training Hospital; İzmir-Turkey. kilicaslanbaris@yahoo.com.[Affiliation]"

Article Synopsis
  • Antenatal hydronephrosis involves swelling in a fetus's kidneys, making it crucial to differentiate between serious cases needing long-term care and those needing little intervention.
  • The study compared two guidelines for managing antenatal hydronephrosis, focusing on identifying their effectiveness in various factors like detection rates, imaging requirements, and patient outcomes.
  • Results showed the newer guideline led to fewer tests, reduced radiation exposure, and less need for surgical interventions compared to the older guideline.
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Objectives: This study aims to compare the elastographic properties of the ovaries of patients with poor ovarian response (POR) with healthy controls by using real-time ultrasound tissue elastography and to investigate the predictive value of ovarian strain ratio (OSR) in the diagnosis of POR.

Materials And Methods: A cross-sectional study was conducted among infertility patients. OSR measurements of 46 women diagnosed with POR and 41 healthy controls with male infertility were performed by real-time ultrasound tissue elastography.

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Background: Endotracheal suctioning is a procedure used by neonatal intensive care unit nurses to maximize oxygenation and clear airways of secretions, and is one of the most common painful procedures causing stress in intubated newborns.

Aim: This aim of this study is to compare the effects of open and closed endotracheal suctioning on pain, peak heart rate and oxygen saturation in neonates on mechanicalventilation.

Materials And Methods: This experimental-design study was conducted on 30 newborns who were mechanically ventilated in the tertiary neonatal intensive care unit of a public hospital.

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Clinical and genetic delineation of autosomal recessive and dominant ACTL6B-related developmental brain disorders.

Genet Med

September 2024

Department of Neuromuscular Diseases, University College London, Queen Square, Institute of Neurology, WC1N 3BG London, UK. Electronic address:

Purpose: This study aims to comprehensively delineate the phenotypic spectrum of ACTL6B-related disorders, previously associated with both autosomal recessive and autosomal dominant neurodevelopmental disorders. Molecularly, the role of the nucleolar protein ACTL6B in contributing to the disease has remained unclear.

Methods: We identified 105 affected individuals, including 39 previously reported cases, and systematically analysed detailed clinical and genetic data for all individuals.

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Mucoperiosteal and lacrimal sac flap anastomosis with ligating clips in revision dacryocystorhinostomy.

Eur Arch Otorhinolaryngol

January 2025

Department of Otorhinolaryngology, Head and Neck Surgery, University of Health Sciences Izmir Tepecik Training and Research Hospital, Gaziler Bulvarı No:468 Yenişehir, Konak, İzmir, Turkey.

Background: Although endoscopic dacryocystorhinostomy (EDCR) has been performed successfully in primary and revision cases, there has yet to be a consensus on the best surgical approach.

Methods: Excessive granulation, adhesion, and fibrosis, the main causes of unsuccessful EDCR, should be expected more frequently in revision surgery. Anastomosis by ligating the nasal mucoperiosteum and lacrimal sac flaps with clips can minimise the surface of exposed bone, therefore, the possibility of stenosis and failure of the dacryocystorhinostomy.

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Article Synopsis
  • Pediatric Burkitt lymphoma (pBL) is a fast-growing cancer in children that requires timely diagnosis and treatment, with microRNAs (miRNAs) playing a critical role in understanding the disease's prognosis.
  • The study utilized microRNA sequencing to identify differentially expressed miRNAs in both tumor tissues and plasma from pBL patients, highlighting their potential as diagnostic and prognostic biomarkers.
  • The results showed that specific circulating and tissue miRNAs were significantly higher in pBL cases, opening avenues for improved diagnostic methods and survival predictions.
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Objectives: The aim of the study is to assess the prevalence and clinical features of headache in patients treated with botulinum toxin for blepharospasm and hemifacial spasm. In addition, our secondary aim was to identify potential factors influencing the development of these headaches.

Methods: A total of 70 patients who were treated with on a botulinum toxin A for dystonia treatment in our clinic between January 2023 and March 2023 were retrospectively screened, and the clinical and demographic characteristics of the patients who reported headache complaints after the last botulinum toxin treatment were examined.

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Introduction: In this study, we aimed to investigate the clinical effects of COVID-19 infection and vaccines on Myasthenia gravis (MG) during the pandemic.

Methods: A total of 141 MG patients between April 2020 and December 2021 were retrospectively analyzed. Data including demographic and clinical characteristics of patients, COVID-19 test results, and vaccine types (mRNA-BNT162b2 and/or inactivated-CoronaVac) were recorded.

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This study was aimed at determining the spiritual care and comfort needs of patients having undergone open-heart surgery. This cross-sectional descriptive study was conducted with 147 patients in the Cardiovascular Surgery Intensive Care Unit of a training and research hospital in Izmir, a province in western Turkey, between May 1, 2022 and November 1, 2022. The comfort level of the patients who had undergone open-heart surgery was moderate, and the levels of their spiritual care needs were high.

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Introduction: This article attempts to provide a comprehensive review of the learning objectives and importance of the supine percutaneous nephrolithotomy (PCNL) technique.

Material Method: We retrospectively reviewed the cases of Supine PCNL between January 2018 and January 2024. We divided the groups into 3: residents between 2 and 3 years (Group 1), residents between 4 and 5 years (Group 2), and endourologist (Group 3).

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Aim: To determine the role of preoperative MRI in the diagnosis and treatment of patients with granulosa cell tumors (GCTs) of the ovary.

Materials And Methods: Twenty-four patients who were operated on between 2018 and 2022 and who were pathologically diagnosed with GHT and met the inclusion criteria were retrospectively examined. The findings were compared with the patients' demographic data, symptoms, surgical findings (laterality, stage, lymph node involvement, endometrial pathology, tumor size), and CA-125 levels.

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Long-term outcomes after breast cancer liver metastasis surgery: A European, retrospective, snapshot study (LIBREAST STUDY).

Surg Oncol

December 2024

Department of Surgery, Hospital Universitario Virgen de Las Nieves, Instituto de Investigación Biosanitaria Ibs.GRANADA, School of Medicine, University of Granada, Granada, Spain.

Article Synopsis
  • Breast cancer is prevalent among women, with 20-30% of patients developing metastases, primarily affecting the liver. Patients with liver metastases have a wide range of survival rates, influenced by various factors.
  • This study aimed to assess the long-term survival and disease-free outcomes for patients who had surgery for liver metastases stemming from breast cancer.
  • Results indicated that surgery can enhance long-term survival, with specific patient characteristics (like health status, hormone receptor positivity, and prior treatments) linked to improved outcomes.
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Article Synopsis
  • * A study evaluated levels of essential micronutrients such as vitamin B12, D, iron, and calcium in 364 PPC patients, revealing that 96.9% had at least one deficiency, particularly in iron, calcium, and vitamin D.
  • * The findings suggest that addressing these micronutrient deficiencies is crucial for improving nutritional management and overall treatment for PPC patients.
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Article Synopsis
  • In Turkey, a single-dose varicella vaccine was introduced in February 2013, aiming to reduce hospitalizations related to chickenpox among children under 18 years old.
  • A study analyzed hospitalization data from 2008 to 2018, comparing rates before and after the vaccine's introduction, finding a significant decrease in hospitalizations (3.79 to 2.87 per 100,000 children per year).
  • The most notable reduction was in children aged 1-5 years, with a 60.2% drop in hospitalizations post-vaccine, demonstrating the vaccine's effectiveness in preventing severe cases of varicella.
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Article Synopsis
  • Sodium-glucose cotransporter-2 inhibitors (SGLT2i) help lower blood glucose and sodium levels by promoting their excretion in urine, leading to benefits like reduced heart failure (HF) hospitalizations in patients with type 2 diabetes (T2DM) and cardiovascular (CV) risks.
  • Clinical trials like DAPA-HF and EMPEROR-Reduced demonstrate that SGLT2i medications (dapagliflozin and empagliflozin) significantly reduce CV mortality and HF hospitalizations in heart failure patients, whether they have T2DM or not.
  • Recent studies, including EMPEROR-Preserved and DELIVER, also support the effectiveness of SGLT2is in treating heart
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Article Synopsis
  • Artificial intelligence in medicine usually faces challenges related to small, non-diverse patient data due to privacy concerns, but federated learning (FL) offers a solution by allowing training across different hospitals without sharing sensitive data.
  • The newly developed FL-PedBrain platform is specifically designed for pediatric brain tumors, enabling collaborative training for tumor classification and segmentation across 19 international centers, addressing the lack of diverse datasets in this area.
  • FL-PedBrain shows impressive performance metrics, maintaining almost equivalent accuracy to centralized data training while significantly improving segmentation performance by 20 to 30% at external sites, and allows for the examination of data variability in real-world situations.
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Introduction: We aimed to demonstrate the sensitivity of frozen section for patients with adult granulosa cell tumor (AGCT) and analyze the clinico-pathological factors that may be associated with sensitivity.

Material Methods: This is a multicenter study including data of 10 Gynecological Oncology Departments. Frozen-section results of patients who had ovarian AGCT at the final pathology report were retrospectively analyzed.

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Purpose: To discern whether reduced infection rates were attributed to antiseptic solutions or mechanical rectal irrigation.

Patients And Methods: After receiving ethical approval, the study included patients who underwent transrectal prostate biopsy due to elevated PSA or abnormal digital rectal examination findings, and prostate cancer under active surveillance, at Tepecik Training and Research Hospital between April 2022 and June 2023. Standard antibiotic prophylaxis was administered.

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Background: We aimed to investigate the effect of the haemoglobin, albumin, lymphocyte and platelet (HALP) score on pathologic results and bladder cancer recurrence (BCR) in patients operated for upper urinary tract tumours (UTUCs).

Material And Methods: HALP scores of all patients were calculated. Demographic data, preoperative blood parameters, pathologic data and the BCR development status of patients with low and high HALP scores were compared.

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Background: The increasing number of people living with HIV requires a simple and easy-to-use quality of life (QoL) scale for people living with HIV (PLWH). This study aims to adapt the PozQoL scale into Turkish and assess its reliability and validity for the PLWH population in Turkey.

Methods: Translation-back-translation methodology was employed, and face-to-face interviews were conducted with 130 patients using the PozQoL, socio-demographic, and clinical data questionnaire.

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Three computed tomography (CT)-based classifications, including Haraguchi, Bartoníček-Rammelt, and Mason-Molloy systems, have been developed to better determine the characteristics of posterior malleolus fractures (PMFs). The aims of this study were (1) to determine the intra- and inter-observer reliability of the computed tomography-based classification systems and (2) to investigate the clinical experience and expertise on their reliabilities. Sixty-seven preoperative ankle CT scans of 67 adult patients with "ankle fracture with the involvement of the posterior malleolus"'' were retrospectively identified.

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Myasthenia Gravis (MG) is a rare neurological disease. Although there are intensive efforts, the underlying mechanism of MG still has not been fully elucidated, and early diagnosis is still a question mark. Diagnostic paraclinical tests are also time-consuming, burden patients financially, and sometimes all test results can be negative.

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Background: COVID-19 has inevitably influenced health systems. HIV testing rates have been reduced, and access to antiretroviral treatment has been scaled down. We evaluated the impact of COVID-19 on the management of people living with HIV (PLWH) in Türkiye.

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Article Synopsis
  • This study analyzed the differences in clinical presentations and severity of influenza A (FLUA) and influenza B (FLUB) in hospitalized children from 2010 to 2020.
  • Among 343 patients, FLUA was more prevalent (75.8%) than FLUB (24.2%), with FLUB linked to higher rates of headache and abdominal pain, particularly in the 3-9 age group.
  • Children aged 0-2 with FLUA had a significantly higher chance of being admitted to the pediatric intensive care unit (PICU) compared to those with FLUB, emphasizing the need for increased attention for this age group.
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Article Synopsis
  • * A new forecasting model was developed to predict future consumption of coagulation tests like PTT, D-dimer, and fibrinogen, using historical data and examining their variability during the pandemic.
  • * The model utilized data from December 2018 to July 2021, analyzing monthly test consumption and admission numbers through a nonlinear autoregressive artificial neural network (NARX) in MATLAB, with a focus on validating the model's accuracy from January to July 2021.
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