3 results match your criteria: "Tennessee. University of Tennessee Health Science Center[Affiliation]"
Single-cell RNA sequencing reveals peripheral blood mononuclear immune cell landscape associated with operational tolerance in a kidney transplant recipient.
Am J Transplant
September 2023
Surgical Sciences Division, Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA. Electronic address:
Operational tolerance (OT) after kidney transplantation is defined as stable graft acceptance without the need for immunosuppression therapy. However, it is not clear which cellular and molecular pathways are driving tolerance in these patients. In this first-of-its-kind pilot study, we assessed the immune landscape associated with OT using single-cell analyses.
View Article and Find Full Text PDFNK cell genotype and phenotype at diagnosis of acute lymphoblastic leukemia correlate with postinduction residual disease.
Clin Cancer Res
December 2014
Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, Tennessee. University of Tennessee Health Science Center, Memphis, Tennessee.
Purpose: Not all natural killer (NK) cells are equally cytotoxic against leukemia because of differences in receptor gene content and surface expression. We correlated NK cell genotype and phenotype at diagnosis of childhood acute lymphoblastic leukemia (ALL) with minimal residual disease (MRD) after induction chemotherapy.
Experimental Design: The NK cells and leukemia blasts of 244 patients were analyzed at diagnosis by killer-cell immunoglobulin-like receptor (KIR) typing and immunophenotyping.
Anal intraepithelial neoplasia in women with genital intraepithelial neoplasia.
Obstet Gynecol
September 2010
From the Department of Obstetrics & Gynecology, University of Tennessee-West Clinic, Memphis, Tennessee; the Department of Obstetrics and Gynecology, University of Tennessee-University of Tennessee Health Science Center, Memphis, Tennessee; the Division of Gynecologic Oncology, West Clinic, Memphis, Tennessee; the Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennessee; and the Department of Obstetrics and Gynecology, The University of Michigan Hospitals, Ann Arbor, Michigan.
Objective: To estimate the prevalence of anal intraepithelial neoplasia in heterosexual women with genital intraepithelial neoplasia, and to compare anal cytology with colposcopy for their effectiveness in anal intraepithelial neoplasia screening.
Methods: Women with confirmed intraepithelial neoplasia on the cervix, vagina, or vulva were referred for gynecologic oncology care. All patients underwent anal cytology and high-resolution anoscopy.