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Preoperative Risk and the Association between Hypotension and Postoperative Acute Kidney Injury.

Anesthesiology

March 2020

From the University of Michigan Medical School, Departments of Anesthesiology (M.R.M., A.M.S., M.L.B., D.A.C., A.J., M.C.E., L.S., K.K.T., S.K.) Internal Medicine (M.H.), Ann Arbor, Michigan University of Virginia Health System, Department of Anesthesiology and Neurosurgery, Charlottesville, Virginia (B.I.N.) Vanderbilt University Medical Center, Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine, Nashville, Tennessee (R.E.F.) Columbia University Medical Center, Department of Anesthesiology, New York, New York (M.K.) University of Chicago Medical Center, Department of Anesthesia and Critical Care, Chicago, Illinois (G.R.). Oregon Health & Science University, Department of Anesthesiology, Portland, Oregon Saint Joseph Mercy Health System, Department of Anesthesiology, Ann Arbor, Michigan University of Virginia Health System, Department of Anesthesiology, Charlottesville, Virginia University of Pennsylvania Health System, Department of Anesthesiology, Philadelphia, Pennsylvania Columbia University Medical Center, Department of Anesthesiology, New York, New York Beaumont Hospital of Troy, Michigan, Department of Anesthesiology, Troy, Michigan Beaumont Hospital of Dearborn, Michigan, Department of Anesthesiology, Dearborn, Michigan Columbia University Medical Center, Department of Anesthesiology, New York, New York Beaumont Health, Farmington Hills, Michigan University of Oklahoma Health Sciences Center, Department of Anesthesiology, Oklahoma City, Oklahoma Bronson Healthcare, Kalamazoo, Michigan University of Tennessee Medical Center, Department of Anesthesiology, Knoxville, Tennessee Cleveland Clinic, Anesthesiology Institute, Cleveland, Ohio St. Joseph Mercy Oakland, Pontiac, Michigan Weill Cornell Medical College, Department of Anesthesiology, New York, New York Washington University School of Medicine, Department of Anesthesiology, St. Louis, Missouri University of Colorado, Department of Anesthesiology, Aurora, Colorado University Medical Center Utrecht, Department of Anesthesiology, Utrecht, The Netherlands Academic Medical Center, Department of Anesthesiology, Amsterdam, The Netherlands Mercy Health, Muskegon, Michigan Bronson Healthcare, Battle Creek, Michigan Wake Forest School of Medicine, Department of Anesthesiology, Winston-Salem, North Carolina St. Mary Mercy Hospital, Livonia, Michigan University of Washington, Department of Anesthesiology and Pain Medicine, Seattle, Washington University of Vermont College of Medicine, Department of Anesthesiology, Burlington, Vermont Sparrow Health System, Lansing, Michigan NYU Langone Medical Center, Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York, New York Vanderbilt University Medical Center, Department of Anesthesiology, Nashville, Tennessee Holland Hospital, Holland, Michigan.

Background: Despite the significant healthcare impact of acute kidney injury, little is known regarding prevention. Single-center data have implicated hypotension in developing postoperative acute kidney injury. The generalizability of this finding and the interaction between hypotension and baseline patient disease burden remain unknown.

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