233 results match your criteria: "Telangiectatic Osteosarcoma"

Nasal telangiectatic osteosarcoma with direct extension to the brain in a domestic shorthair cat.

JFMS Open Rep

December 2024

Laboratory of Veterinary Pathology and Forensics, College of Agronomy and Veterinary Medicine (FAV), University of Brasília (UnB), Asa Norte, Federal District, Brazil.

Case Summary: This case report describes the clinical and pathological features of telangiectatic osteosarcoma (TOS) with brain invasion in a 4-year-old female domestic shorthair cat. The cat presented with respiratory distress, epistaxis, anorexia and significant nasal obstruction. A rhinoscopy revealed an amorphous white neoformation in the left nasal cavity.

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Imaging of Osteosarcoma: Presenting Findings, Metastatic Patterns, and Features Related to Prognosis.

J Clin Med

September 2024

Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.

Article Synopsis
  • Osteosarcomas are rare bone tumors that make up less than 1% of all cancers and are most commonly found in children, second only to multiple myeloma among primary bone tumors.
  • The imaging characteristics of osteosarcomas vary by histological subtype, with conventional types showing mixed radiological patterns and aggressive features, while telangiectatic forms are typically purely lytic.
  • The review emphasizes the relationship between imaging features and patient outcomes, including treatment response and survival, highlighting important parameters for medical professionals involved in the management of these tumors.
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Intra-abdominal telangiectatic osteosarcoma: a case report.

J Med Case Rep

August 2024

Division of Orthopaedic Surgery, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Background: Telangiectatic osteosarcoma is rare and it rarely affects flat bones, especially the bones of the pelvis. It is uncommon for telangiectatic osteosarcoma to be considered as a differential diagnosis when assessing a large intrabdominal mass.

Case Report: We present our case of a 33-year-old African female who presented with a sizeable telangiectatic osteosarcoma of the left iliac bone.

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Telangiectatic osteosarcoma (TOS) is a rare variant of osteosarcoma that typically affects young individuals and long bones. The case under discussion was seen in the mandible of a 57-year-old female and had rapidly grown in size within a week. Microscopically, the tumour was characterised by large vascular cavities surrounded by anaplastic cells.

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Primary mandibular telangiectatic osteosarcomas are very rare lesions, with only nine cases reported. Histologically, these lesions show multiple cystic blood-filled cavities traversed by neoplastic bone in septa lined by high-grade malignant cells. Here, we report an 81-year-old woman who presented with a mandibular mass, which was surgically resected and analyzed by histologic examination and whole exome DNA sequencing.

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Angiosarcoma of bone is very rare entity, accounting for less than 1% of all primary bone sarcomas with associated poor prognosis. We hereby present a case report of angiosarcoma of tibia in a young boy and reviewed its literature and management of the disease. A 21-year young male presented to us with complaints of pain and swelling over left lower leg since last 3 months.

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The purpose of this review is to increase awareness about the evolution and development of current trends in the diagnosis and treatment of aneurysmal bone cysts (ABCs). ABCs are benign, but locally aggressive bone tumors that mainly affect children. ABCs comprise 1% of all primary bone tumors and occur most frequently during the first two decades of life.

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Telangiectatic osteosarcoma in four dogs: Cytologic, histopathologic, cytochemical, and immunohistochemical findings.

Vet Clin Pathol

March 2024

Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts, USA.

Telangiectatic osteosarcoma is a rare variant of osteosarcoma histologically and clinically similar to hemangiosarcoma (HSA). This case series describes the imaging and cytologic features of four histologically confirmed telangiectatic osteosarcomas, including the use of cytochemical stains. Alkaline phosphatase (ALP) was applied to Wright-Giemsa-stained cytology slides, and Factor VIII immunohistochemistry was evaluated.

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Telangiectatic osteosarcoma of maxilla in a young child.

Oral Oncol

December 2023

Oral Pathology and Microbiology, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India. Electronic address:

Article Synopsis
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Preoperative Mohs Paste Treatment for a Subcutaneous Sarcoma and a Skin Ulcer to Prevent Intraoperative Bleeding.

J Orthop Case Rep

October 2023

Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin, Kawahara-Cho, Sakyo-Ku, Kyoto 606-8507, Japan.

Introduction: Mohs paste has a zinc chloride component and the ability to coagulate tissue. Mohs chemosurgery or surgery is a method by which coagulated tissue is removed and can be repeated until the tumor disappears. The palliative purpose of Mohs chemosurgery or surgery is to control bleeding or exudate from a malignancy with a skin ulcer.

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Osteosarcoma (OS) is one of the most prevalent malignant bone tumors. The proportion of patients with limb OS was relatively high. Lung metastasis (LM) and bone metastasis are the first and second most common metastatic types of OS, respectively.

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Imaging findings of primary breast telangiectatic osteosarcoma: a case description.

Quant Imaging Med Surg

September 2023

Department of Ultrasound, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.

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To investigate the distribution and characteristics of gene mutations in osteosarcoma, and to analyze the frequency and types of detectable mutations, and to identify potential targets for individualized treatment of osteosarcoma. The fresh tissue or paraffin-embedded tissue samples of 64 cases of osteosarcoma that were surgically resected or biopsied and then subject to next generation sequencing, were collected from Beijing Jishuitan Hospital, China from November 2018 to December 2021. The tumor DNA was extracted to detect the somatic and germline mutations using targeted sequencing technology.

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Prognostic analysis of telangiectatic osteosarcoma of the extremities.

Front Oncol

February 2023

Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China.

Background And Objectives: Telangiectatic osteosarcoma (TOS) is a rare but highly malignant subtype of osteosarcoma. Although surgical treatment is the primary treatment modality for osteosarcoma, evidence on the benefits of different surgical methods in patients with TOS is lacking. This study aimed to compare the effects of different surgical and adjuvant treatments on overall survival of TOS, and the association of patient demographics, oncological characteristics, and socioeconomic status on treatment outcomes.

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Lung and bone metastases patterns in osteosarcoma: Chemotherapy improves overall survival.

Medicine (Baltimore)

January 2023

Department of Orthopedics, Cangzhou Central Hospital, Cangzhou, Hebei, P.R. China.

Osteosarcoma (OS) is a malignant tumor originating from the mesenchymal tissue. Simultaneous reports of lung and bone metastases (BM) in OS are rare in the literature. A total of 353 new cases of lung metastases (LM), 93 new cases of BM, and 59 new cases of LM and BM were diagnosed in the Surveillance, Epidemiology and End Results (SEER) database from 2010 to 2019.

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Diaphyseal Tibial Osteosarcoma With Myiasis.

Cureus

December 2022

Department of Orthopaedic Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.

Osteosarcoma is a tumour that can originate in any bone and is the most frequent malignant tumour of the skeleton. It typically develops close to the metaphyseal growth plates in the limbs' long bones. The three most prevalent places are the femur, tibia, and humerus.

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Bone cysts are tumor-like lesions of bone. These are primarily of two types: simple or unicameral and aneurysmal bone cysts (ABC). An aneurysmal bone cyst (ABC) is a blood-filled cyst that usually occurs over the metaphysis of long bones, flat bones, and vertebrae.

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Lung metastases pattern in limb osteosarcoma: A population-based study from 2010 to 2018.

Medicine (Baltimore)

November 2022

Drug Clinical Trial Institution, Cangzhou Central Hospital, Cangzhou, Hebei, P.R. China.

Osteosarcoma (OS) is one of the most prevalent malignant bone tumors. The proportion of limb OS is relatively high, and lung metastases (LM) are one of the most prevalent metastatic types. A total of 1694 new cases of limb OS were identified in the surveillance, epidemiology and end results (SEER) database from 2010 to 2018.

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Aneurysmal bone cyst (ABC) is a benign but locally aggressive lesion that predominantly affects children and young adults. ABC, which accounts for approximately 70% of the cases, is now recognized to be a true neoplasm, whereas ABC-like changes associated to other bone neoplasms (also referred in the literature as secondary ABC) accounts for the remaining 30%. The solid variant of ABC is also considered a true neoplasm but is rare.

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A rare case of sino-nasal aneurysmal bone cyst.

Radiol Case Rep

October 2022

Department of Radiology, Madigan Army Medical Center, 9040A Jackson Ave, Joint Base Lewis-McChord, WA 98431 USA.

Aneurysmal bone cysts (ABC) are rare in the paranasal sinuses. They are benign expansile multicystic masses containing blood-filled spaces which typically occur in the long bones of pediatric patients. The lesion often produces symptoms due to the compression of adjacent structures or pathological fracture and depends on localization.

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Telangiectatic Osteosarcoma of the Tibiotarsus in a North Island Brown Kiwi (Apteryx mantelli).

J Wildl Dis

October 2022

Tāwharau Ora, School of Veterinary Science, Massey University, University Avenue, Fitzherbert, Palmerston North 4442, New Zealand.

A North Island brown kiwi (Apteryx mantelli) with lameness and weight loss had a telangiectatic osteosarcoma. The left proximal tibiotarsus had bony lysis with multiple blood-filled spaces separated by thick fibrous septa and neoplastic mesenchymal cells producing osteoid (5-bromo-4-chloro-3'-indolyl phosphate/nitro blue tetrazolium positive on cytology). No metastases were noted on necropsy.

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