Deep neck infections in cervical injection drug users.

Objectives/hypothesis: To characterize deep neck infections (DNI) in adult intravenous drug users (IDUs) who injected illicit substances to their neck, in comparison to DNI in non-IDUs.

Study Design: Retrospective, cohort study.

Methods: Data were retrieved from medical charts of adult DNI patients in a secondary hospital during 2000-2013.

Ethical and clinical dilemmas in patients with head and neck tumors visiting a field hospital in the Philippines.

Objective: To describe clinical and ethical dilemmas in patients presenting with head and neck (H&N) tumors to a field hospital in the "subacute" period following a typhoon.

Methods: We retrospectively reviewed charts of H&N patients presenting to an integrated Israeli-Filipino medical facility, which was operated more than 11 days.

Results: Of the 1,844 adult patients examined, 85 (5 percent) presented with H&N tumors.

Acute mastoiditis in the pneumococcal conjugate vaccine era.

Following the introduction of the 7- and 13-valent pneumococcal conjugate vaccines, we observed an inverse relationship between the increasing rate of immunized children and the proportion of middle ear fluid cultures collected during acute mastoiditis episodes that tested positive for Streptococcus pneumoniae among a subset of children 0 to 6 years old who had initially presented with severe acute otitis media and had bacterial cultures collected during tympanocentesis or from spontaneous otorrhea.

Acute limb ischemia in cancer patients: aggressive treatment is justified.

Background: The outcome of cancer patients with acute limb ischemia (ALI) is not well defined. The purpose of this study is to report our experience treating patients with active malignancy who developed ALI and compare their outcome with non-cancer patients.

Methods: A retrospective review of patients treated for ALI between 2009 and 2012 with ALI.

Survival after intervention in patients with low gradient severe aortic stenosis and preserved left ventricular function.

Objective: The outcome of aortic valve replacement for patients with low gradient severe aortic stenosis and preserved ejection fraction has been debated. The aim of the present study was to evaluate the effect of aortic valve intervention on survival in that group.

Methods: A cohort of 416 consecutive patients with low gradient severe aortic stenosis (aortic valve area, ≤ 1 cm(2); mean pressure gradient, <40 mm Hg) and preserved ejection fraction (≥ 50%) were identified from the Sheba Medical Center echocardiography database.

Pediatric otolaryngology in a field hospital in the Philippines.

Background: Major natural disasters adversely affect local medical services and resources. We sought to characterize pediatric patients presenting with otolaryngology-head and neck surgery (OTO-HNS)-related diseases/injuries to a field hospital over 11 days of operation, which was deployed to assist the healthcare facilities in Bogo, the Philippines, in the aftermath of typhoon Haiyan (Yolanda).

Methods: We reviewed charts of pediatric patients aged 0-18 years visiting our field hospital, who presented with OTO-HNS-related diseases/injuries.

Urinary stone composition in Israel: current status and variation with age and sex--a bicenter study.

Background And Purpose: The epidemiologic data regarding stone composition in Israel are based on anachronistic methods of stone analysis. Historically, Israel was noted for an unusually high percentage of uric acid stones. The aim of the study was to describe the current stone composition distribution in Israel, using modern techniques of urinary stone analysis.

Wearing time as a measure of success of scleral lenses for patients with irregular astigmatism.

Objectives: To evaluate the visual correction and clinical performance with scleral contact lenses (CL) for the visual rehabilitation of irregular astigmatism and to report the effect of brief wearing breaks on the wearing time and success rate.

Methods: A retrospective review was performed on consecutive patients who were fitted with scleral CL because of irregular astigmatism following failure of other optical corrections. Visual acuity (VA) and wearing times were abstracted.

The impact of retrograde intrarenal surgery for asymptomatic renal stones in patients undergoing ureteroscopy for a symptomatic ureteral stone.

Background And Purpose: In the era of rigid ureteroscopy (URS) for ureteral stones, asymptomatic renal stones were often left in place. With the advent of flexible URS, however, the treatment of such renal stones became an attractive option. Data are scarce regarding the impact of retrograde intrarenal surgery (RIRS) performed at the time of URS for a symptomatic ureteral stone in comparison with ureteral stone removal alone.

Intra-auricular sinus: first description of a variant of the pre-auricular cyst.

Objective: The aim of this study was to describe a rare intra-auricular sinus. An otherwise healthy 15-year-old girl presented with recurrent infections in her right pinna from early infancy. Physical examination revealed a draining sinus which opened to the descending helical limb, while its cystic component was entrapped within the cartilaginous antitragus.

Isolated myoclonus of the vocal folds.

Objective: Laryngeal manifestations of stroke play a significant role in the morbidity and mortality among affected patients. The objective of this article was to describe unique myoclonic vocal fold movement disorder, which is an unusual post-stroke manifestation.

Study Design: A retrospective case study.

Colon cancer cells expressing cell surface GRP78 as a marker for reduced tumorigenicity.

Background: The glucose regulated heat shock protein 78 (GRP78) is a central regulator of ER (endoplasmic reticulum) stress due to its pro-survival property. Up regulated GRP78 expression in tumor cells has been correlated with aggressive malignancies whereas some reports have predicted an improved prognosis. Over-expression of GRP78 in the ER promotes its localization to the cell surface on several cell types including tumor cells.

The role of gene expression profiling in the management of breast cancer patients.

Breast cancer specialists often find it difficult to decide whether or not to recommend on chemotherapy in women with presumed low risk for future development of metastatic disease. This decision is usually based on well-established clinical and histopathological scoring tools. During recent years, an additional way to estimate the risk for advanced disease comes from gene expression profiling of the breast cancer tumor cells.

Otolaryngological aspects of sudden infant death syndrome.

Introduction: Sudden infant death syndrome (SIDS) is characterized by the sudden death of an apparently otherwise healthy infant, typically during sleep, and with no obvious case after a thorough post-mortem and scene death examination.

Objective: To address the problem from the otolaryngologist's perspective, describe relevant pathologies, discuss controversies and suggest preventive measures in high-risk populations.

Methodology: A MEDLINE search and hand search were conducted to identify reports published between 1969 and 2011 in the English language on the pathophysiology of SIDS related to the head and neck organs.

Laparoscopic adnexal transposition: novel surgical technique.

Treatment of some cancers diagnosed at an early stage with expectation of prolonged survival has permitted the consideration of salvaging the reproductive and hormonal function of premenopausal female patients. When radiation to the pelvic area is part of treatment, this will almost always result in ovarian failure. To protect the ovaries, an oophoropexy may be performed, which involves moving the ovaries away from the radiation field.

Lymph node metastasis in nasal vestibule cancer: a review.

Background: Squamous cell carcinoma of the nasal vestibule (SCCNV) is an uncommon malignancy. Our purpose is to define the incidence of simultaneous and delayed regional metastasis in SCCNV according to the available literature.

Methods: Articles discussing SCCNV and addressing the issue of regional lymph node metastases were reviewed.

Clinical challenges of adoption: Views from Montreal and Tel Aviv.

Adoption is accompanied by well-known risk factors that contribute to unique clinical challenges for children, parents, and clinicians. Adoption also serves to illustrate issues that remain relatively "silent" in the typical transition to parenthood. In this article, the authors review the normal developmental challenges that parents face during adoption, the adoption-related risk factors that may impinge on the child's development and attachment process, and the impact of adoption on the child's development of identity and filiations.

An infant who was born with a life-threatening skin disease: Various aspects of triadic psychotherapy.

A longitudinal case study of a 3-year-old toddler, born with a congenital, severe, life-threatening skin disease, with comorbid diagnoses of failure to thrive and feeding disorder, is described and discussed. The referral, diagnostic, and therapeutic processes are described, and the main themes of the treatment sessions are presented in the associative order that they occurred. The understanding of the case is very much based on the "me-skin'' concept.

Sudden brief unilateral tapering tinnitus: prevalence and properties.

Objective: To systematically characterize unilateral tinnitus typically lasting less than a minute.

Study Design: Observational study.

Setting: Outpatient clinic in a tertiary referral hospital.

Head and neck manifestations of 22q11.2 deletion syndromes.

The allelic loss of 22q11.2 results in various developmental failures of pharyngeal pouch derivatives ("22q11.2 deletion syndromes", 22q.