3,066 results match your criteria: "Tel-Aviv Medical Center[Affiliation]"

COVID-19-related pneumonia is typically diagnosed using chest x-ray or computed tomography images. However, these techniques can only be used in hospitals. In contrast, thermal cameras are portable, inexpensive devices that can be connected to smartphones.

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Objectives: To assess height and weight as possible sex-specific risk factors for bilateral myopia among young adults.

Methods: We conducted a cross-sectional study including 101,438 pre-enlisted young adult males and females, aged 17.4 ± 0.

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Weight loss and response to chemotherapy in pediatric patients with osteosarcoma.

Eur J Clin Nutr

June 2024

Department of Pediatric Hemato-Oncology, Dana Children's Hospital, Tel Aviv Medical Center, Tel Aviv, Israel, affiliated to the Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Weight loss and malnutrition are common findings in pediatric oncology patients, but their prognostic significance is controversial. We sought to evaluate the correlation between weight loss and response to neo-adjuvant chemotherapy in pediatric patients with osteosarcoma.

Procedure: All medical files of patients treated for osteosarcoma in a single pediatric haemato-oncology center between January 2011 and October 2022 were retrospectively reviewed.

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Background: We compared the effect of perioperative COVID-19, before and after vaccination, on 30-day mortality after cardiac surgery.

Methods: Data was extracted from several national registries. The study period was March 1, 2020-March 31, 2022.

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Background: High ultra-processed food (UPF) consumption is associated with the development of various diet-related non-communicable diseases, especially obesity and type 2 diabetes. The present study aimed to systematically review the association between UPF consumption and non-alcoholic fatty liver disease (NAFLD) and its leading risk factors; metabolic syndrome (MetS) and insulin resistance (IR).

Methods: A comprehensive search was conducted in PubMed, Scopus, Embase, Web of Science, CINAHL, and Cochrane (March 2023), and references of the identified articles were checked.

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Background: The underlying mechanisms responsible for the clinical benefits following coronary sinus narrowing and pressure elevation remain unclear. The present study aims to investigate whether coronary sinus narrowing improves the indexes of coronary microcirculatory function.

Methods: Patients with refractory angina who had a clinical indication for reducer implantation underwent invasive physiological assessments before and 4 months after the procedure.

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Medical Cannabis Increases Appetite but Not Body Weight in Patients with Inflammatory Bowel Diseases.

Nutrients

December 2023

Department of Gastroenterology and Liver Diseases, Tel Aviv Medical Center, Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.

We aimed to elucidate the effect of Medical Cannabis (MC) on appetite and nutritional status among patients with inflammatory bowel disease (IBD). A case series of patients with IBD were initiating treatment with MC for disease-related symptoms, at the IBD clinic of a tertiary referral medical center. Patients' demographics, anthropometrics, medical history and treatment and MC use were systematically recorded.

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Implementation of Artificial Intelligence-Based Computer Vision Model for Sleeve Gastrectomy: Experience in One Tertiary Center.

Obes Surg

February 2024

Division of General Surgery, Bariatric Unit, Tel Aviv Medical Center, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, 6, Weizman St., Tel Aviv, Israel.

Introduction: Sleeve gastrectomy (SG) is the most common metabolic and bariatric procedure performed. Leveraging artificial intelligence (AI) for automated real-time data structuring and annotations of surgical videos has immense potential of clinical applications. This study presents initial real-world implementation of AI-based computer vision model in sleeve gastrectomy (SG) and external validation of accuracy of safety milestone annotations.

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The Impact of Carotid Endarterectomy on Choriocapillaris Perfusion.

Invest Ophthalmol Vis Sci

December 2023

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.

Purpose: The impact of carotid endarterectomy (CEA) on choriocapillaris (CC) perfusion was investigated using swept-source optical coherence tomography angiography (SS-OCTA) imaging before and after surgery in patients with clinically significant carotid artery stenosis (CAS).

Methods: In this prospective observational study, patients with clinically significant CAS undergoing unilateral CEA had SS-OCTA imaging performed in both eyes before and within 1 week after surgery. The percent CC flow deficits (CC FD%) and CC thickness were assessed using previously validated algorithms.

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Digital Mobility Measures: A Window into Real-World Severity and Progression of Parkinson's Disease.

Mov Disord

February 2024

Laboratory for Early Markers of Neurodegeneration (LEMON), Center for the Study of Movement, Cognition and Mobility, Neurological Institute, Tel Aviv Medical Center, Tel Aviv, Israel.

Background: Real-world monitoring using wearable sensors has enormous potential for assessing disease severity and symptoms among persons with Parkinson's disease (PD). Many distinct features can be extracted, reflecting multiple mobility domains. However, it is unclear which digital measures are related to PD severity and are sensitive to disease progression.

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Huge Diaphragmatic Hernia Following Revisional One Anastomosis Gastric Bypass.

Obes Surg

February 2024

Division of General Surgery, Bariatric Unit, Tel Aviv Medical Center, affiliated to Sackler Faculty of Medicine, Tel Aviv University, 6, Weizman St, 6423906, Tel Aviv, Israel.

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Pelvic floor muscle training (PFMT) represent the first-line approach to pelvic floor dysfunctions (PFDs). Recently, studies have shown a synergy between the pelvic floor and abdominal muscles, hypothesizing that the anatomical and functional integrity of the abdominal wall plays a role in the prevention of pelvic floor disorders. Some studies have shown a significant correlation between diastasis recti abdominis (DRA) and stress urinary incontinence (SUI).

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Article Synopsis
  • Postoperative recurrence (POR) is common in Crohn's disease patients after surgery, but can be reduced with preventive treatment; however, there is insufficient data on the best treatment options and timing.
  • A clinical study compared the effectiveness of early treatment with 6-mercaptopurine (6-MP) versus adalimumab in patients after ileocecectomy, finding that adalimumab significantly reduced endoscopic recurrence rates at both 32 and 58 weeks post-surgery.
  • Factors like increased size of the resected bowel, lower body mass index (BMI), and specific lab results were linked to a higher risk of endoscopic recurrence, indicating that adalimumab may be a more effective choice for
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Article Synopsis
  • The study evaluated the effectiveness of two sets of classification criteria for Granulomatosis with Polyangiitis (GPA) in pediatric patients, comparing the ACR/EULAR criteria with the Ankara 2008 criteria.
  • Data from 77 pediatric patients with GPA were analyzed, revealing high sensitivity (94.8%) and specificity (95.3%) for the Ankara criteria, while the ACR/EULAR criteria showed similar rates (89.6% sensitivity and 96.3% specificity).
  • The results indicate that both classification criteria are reliable and perform similarly in diagnosing GPA in children.
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Immune checkpoint inhibitors have revolutionized cancer therapy, yet the efficacy of these treatments is often limited by the heterogeneous and hypoxic tumor microenvironment (TME) of solid tumors. In the TME, programmed death-ligand 1 (PD-L1) expression on cancer cells is mainly regulated by Interferon-gamma (IFN-γ), which induces T cell exhaustion and enables tumor immune evasion. In this study, we demonstrate that acidosis, a common characteristic of solid tumors, significantly increases IFN-γ-induced PD-L1 expression on aggressive cancer cells, thus promoting immune escape.

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Background: Precision surgery is becoming increasingly important in the field of Orthopaedic Oncology. Image-guided percutaneous cryosurgery (CRA) has emerged as a valid treatment modality for extra-abdominal desmoid tumors (EDTs). To date, most CRA procedures use CT-based guidance which fails to properly characterize tumor segments.

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Article Synopsis
  • The ridaforolimus-eluting stent (RES) system, known as EluNIR, uses a unique cobalt alloy and polymer to treat small coronary artery disease with a diameter of 2.25 mm.
  • The study assessed safety and effectiveness through a clinical trial involving 81 patients, with follow-ups at 30 days, 6 months, and 1 year, focusing on achieving low residual stenosis without major adverse events.
  • Results indicated a 98.8% success rate, low rates of complications (1.2% at 30 days and 2.5% at 1 year), and highlighted the EluNIR stent as a valuable option for treating this challenging type of coronary artery issue.*
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An Integrative, Multiparametric Approach to Tricuspid Regurgitation Evaluation: A Case-Based Illustration.

JACC Case Rep

November 2023

Department of Cardiology, Istituto Auxologico Italiano, Istituto di ricovero e cura a carattere scientifico, Milan, Italy.

Echocardiography is the first-line modality for assessing tricuspid regurgitation (TR). In addition to evaluation of the mechanism of TR, echocardiography can provide quantitative parameters of TR severity and assess hemodynamics. This case series demonstrates the importance of integrating multiple parameters in the evaluation of TR and the role of multimodality imaging.

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Artificial phantoms used in photothermal near-infrared laser lithotripsy research generally fail to mimic both the chemical and the physical properties of human stones. Though high-energy, 1 J pulses are capable of fracturing hard human stones into several large fragments along natural boundaries, similar behavior has not been observed in commonly used gypsum plasters like BegoStone. We developed a new brushite-based plaster formulation composed of ≈90% brushite that undergoes rapid fracture in the manner of human stones under fragmentation pulse regimes.

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Photorefractive keratectomy in flat, normal, and steep corneas.

J Cataract Refract Surg

January 2024

From the Department of Ophthalmology, Tel Aviv Medical Center affiliated with the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel (Levinger); Department of Ophthalmology, Assuta-Samson Ashdod Hospital affiliated with the Faculty of Medicine, Ben Gurion University, Beer-Sheva, Israel (Arnon, Pikkel, Yahalomi); Department of Ophthalmology, Rambam Health Care Campus, Haifa, Israel (Mimouni); Bruce and Ruth Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (Mimouni); Care-Vision Laser Centers, Tel-Aviv, Israel (Sela, Munzer, Mimouni).

Purpose: To compare photorefractive keratectomy (PRK) outcomes in patients with different corneal steepness.

Setting: Care-Vision Laser Center, Tel-Aviv, Israel.

Design: Retrospective comparative chart review.

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Background: The administration of an appropriate empirical antibiotic treatment is essential in cirrhosis and severe bacterial infections. We aimed to investigate the predictors of clinical response of empirical antibiotic treatment in a prospective cohort of patients with cirrhosis and bacterial and fungal infections included in the International Club of Ascites "Global Study."

Methods: Patients hospitalized with cirrhosis and bacterial/fungal infection were prospectively enrolled at 46 centers.

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The Pediatric Epilepsy Surgery Interest Group (PESIG) under the auspice of the ISPN Research Committee: Availability of relevant technology and geographical distribution.

Childs Nerv Syst

April 2024

Department of Pediatric Neurosurgery, The Pediatric Brain Center, Dana Children's Hospital, Tel Aviv Medical Center, Tel Aviv University, 6 Weizman Street, Tel Aviv, 64239, Israel.

Purpose: Epilepsy surgery for pediatric drug-resistant epilepsy has been shown to improve seizure control, enhance patient and family QoL, and reduce mortality. However, diagnostic tools and surgical capacity are less accessible worldwide. The International Society Pediatric Neurosurgery (ISPN) has established a Pediatric Epilepsy Surgery Interest Group (PESIG), aiming to enhance global collaboration in research and educational aspects.

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Background: This study investigated the early safety and mid-term outcomes of stepwise implementation of transcatheter aortic valve implantation (TAVI) in Vietnamese patients with severe aortic stenosis (AS) at a single center, following the process of technical transfer.

Methods: From 2017 to 2022, 90 patients with symptomatic severe AS underwent TAVI at a tertiary hospital in Vietnam. The first 30 cases received support for technology transfer from international proctors.

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Shifting Strategies in the Treatment of Pediatric Craniopharyngioma.

Curr Oncol Rep

December 2023

Department of Pediatric Neurosurgery and Pediatric Brain Institute, Dana Dwek Children Hospital, Tel Aviv Medical Center, 6 Weizmann Street, 64239, Tel Aviv, Israel.

Purpose Of Review: Craniopharyngiomas represent one of the most challenging diseases to treat. Despite their benign histology, and after many decades of surgical experience and technological advancements, there is still no clear consensus regarding the most effective management for this tumor. Due to their location and aggressive local characteristics, purely surgical approaches all too often result in unacceptable morbidity.

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