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Anatomic Asymmetry in Sentinel Lymph Node Detection in Endometrial Cancer.

J Minim Invasive Gynecol

August 2021

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology (Drs. Tal, Grinstein, Elyashiv, Ben Shem, Peled, and Levy); Department of Nuclear Medicine (Drs. Goshen and Oksman), Edith Wolfson Medical Center, Holon; Department of Nuclear Medicine, Shamir Medical Center, Tzrifin, Sackler School of Medicine, Tel Aviv University (Dr. Lorberboym), Tel Aviv, Israel.

Article Synopsis
  • The study aimed to assess if combining indocyanine green (ICG) with technetium-99m-filtered sulfur colloid (Tc99m-FSC) enhances the detection of bilateral sentinel lymph nodes (SLNs) in endometrial cancer patients.
  • A total of 111 patients were analyzed, revealing that using both tracers improved bilateral detection rates; ICG performed better than Tc99m-FSC when used alone.
  • The findings suggest that while the combination of both methods provides superior SLN detection, anatomical symmetry between detected nodes is unreliable, indicating caution during unilateral mapping failures.
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