622 results match your criteria: "Teikyo University Hospital[Affiliation]"

Cardiac myxoma with high standardized uptake value of FDG-PET-CT in the right ventricular outflow tract.

Gen Thorac Cardiovasc Surg Cases

December 2024

Department of Cardiovascular Surgery, Teikyo University Hospital, 2-21-1 Kaga, Itabashi-Ku, Tokyo, 173-8606, Japan.

Background: Cardiac myxoma rarely occurs in the right ventricle, and as is a benign disease, it rarely shows high positivity on 18F fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT).

Case Presentation: We present herein the case of a 77-year-old woman who was found to have a heart murmur during a routine health checkup. Further examination revealed a 27-mm tumor in the right ventricular outflow tract (RVOT) and moderate aortic valve stenosis.

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Here, we describe two cases of retained products of conception (RPOC) that were successfully managed with hysteroscopic resection after laparoscopic temporary uterine artery ligation. Both patients were diagnosed with RPOC after early miscarriages. Case 1 was urgently admitted due to massive bleeding and underwent surgery following a blood transfusion.

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Cone Beam Computed Tomography Image-Quality Improvement Using "One-Shot" Super-resolution.

J Imaging Inform Med

December 2024

Graduate School of Medical Care and Technology, Teikyo University, 2-11-1 Kaga, Itabashi-Ku, Tokyo, 173-8605, Japan.

Article Synopsis
  • - Cone beam computed tomography (CBCT) images are useful for visualizing internal organs but often lack the image quality of treatment planning CT images, presenting a significant drawback for medical applications.
  • - A new super-resolution model called "one-shot" super-resolution (OSSR) effectively enhances CBCT image quality using minimal training data by leveraging just the target CBCT image and its matching treatment planning CT image.
  • - In tests involving pelvic images from 30 prostate cancer patients, the OSSR model showed substantial improvements in image quality metrics (RMSE, PSNR, SSIM, NMI) compared to standard methods, achieving performance similar to more data-intensive models like CycleGAN.
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The efficacy and safety of percutaneous coronary intervention (PCI) for coronary artery disease has been established, and approximately 250,000 PCI procedures are performed annually in Japan. However, various complications including life-threatening complications can occur during PCI. Although several bailout procedures have been proposed to address complications during PCI, it is critically important for operators to manage each complication in real catheter rooms with confidence even in emergent situations.

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Article Synopsis
  • - The study compares the hemodynamic performance and clinical outcomes of self-expandable valves (SEV) and balloon-expandable valves (BEV) in patients with small aortic annulus (SAA) undergoing transcatheter aortic valve replacement (TAVR).
  • - Results showed that SEV offered better hemodynamics, with a higher rate of severe prosthesis-patient mismatch and a greater mean pressure gradient in patients receiving BEV, while BEV had lower incidences of paravalvular leakage and new permanent pacemaker implantation.
  • - Overall, both valve types had similar device success rates, indicating that SEV is superior in hemodynamic outcomes but BEV has advantages in reducing certain complications. *
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The first step in treating diabetes mellitus (DM)-related diarrhea is to thoroughly control the serum glucose level. The authors herein describe a 75-year-old man who was diagnosed with type 1 DM when he was 32 years old. The patient lost his appetite due to hot weather and spent a week eating sweets and drinking juice.

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The Joint Committee for Nationwide Survey on colorectal liver metastasis (CRLM) was established to improve treatment outcomes in patients with CRLM. The aim of this study was to evaluate the transition in the characteristics and treatment strategies of patients with CRLM and to analyze the prognostic factors. The data of 5085 patients newly diagnosed between 2013 and 2017 were compared with those of 3820 patients from 2005 and 2007.

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Background: To improve the outcome in newly diagnosed glioblastoma patients with maximal resection, we aimed to evaluate the efficacy and safety of implantation of carmustine wafers (CWs), radiation concomitant with temozolomide and bevacizumab, and maintenance chemotherapy with six cycles of temozolomide and bevacizumab.

Method: This prospective phase II study enrolled glioblastoma patients considered candidates for complete resection (> 90%) of a contrast-enhanced lesion. The CWs were intraoperatively implanted into the resection cavity after achieving maximal resection.

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Background: Mavacamten, a cardiac myosin inhibitor, significantly improved symptoms and cardiac function vs. placebo in patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM) in EXPLORER-HCM. However, the efficacy and safety profiles of mavacamten in Japanese patients are unclear.

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Background/aim: Peritoneal dissemination (PD) is a frequent cause of death in gastric cancer (GC), and there is evidence of an association between protease-activated receptor-1 (PAR1) and the development of PD. This study hypothesized that PD in GC might be influenced by PAR1.

Materials And Methods: The cytotoxic effect of paclitaxel (PTX) on PAR1-transfected MKN45 (MKN45/PAR1) cells was analyzed using the MTT assay, and IC values were determined.

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Bladder cancer treatments are highly aggressive and have strong side effects. Safer and more effective treatments are needed. In this study, Dibenzolium (DIB), a potent NADPH oxidase inhibitor, was evaluated for its anti-tumor effects.

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Rapid and accurate identification of bacterial species is essential for the effective treatment of infectious diseases and suppression of antibiotic-resistant strains. The unique autofluorescence properties of bacterial cells are exploited for rapid and cost-effective identification that is suitable for point-of-care applications. Fluorescence spectroscopy is combined with machine learning to improve the diagnostic accuracy.

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Article Synopsis
  • The study investigates gender disparity in interventional cardiology, focusing on the outcomes of percutaneous coronary interventions (PCIs) performed by female interventionalists in Japan.
  • A total of 447 female operators conducted 35,211 PCIs during the study, showing that female doctors treated more patients with severe heart conditions but had a higher overall success rate than male doctors.
  • Results indicate that female operators had similar in-hospital mortality rates compared to male operators, but the findings highlight the need for increased gender diversity in the field.
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Article Synopsis
  • East Asians typically have smaller aortic valve complexes compared to Western populations, and there’s limited data on TAVI outcomes in Asian patients with large annuli.
  • This study analyzes TAVI results in Asian patients, comparing outcomes between balloon-expandable valves (BEVs) and self-expandable valves (SEVs) by examining data from the OCEAN-TAVI registry.
  • Findings show no significant differences in 3-year all-cause mortality, heart failure rehospitalization rates, or valve function after 2 years between BEV and SEV groups, although SEVs had higher rates of paravalvular leakage and pacemaker implantation.
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Article Synopsis
  • A middle-aged woman diagnosed with breast cancer developed worsening kidney issues, leading to nephrotic syndrome characterized by proteinuria and hematuria.
  • After receiving hormone therapy for her cancer, a kidney biopsy showed signs of IgA nephropathy, ruled out other potential causes.
  • Following breast cancer surgery and radiation, her kidney symptoms improved significantly, indicating a possible paraneoplastic glomerulopathy related to her breast cancer.
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Article Synopsis
  • * Conducted from 2013 to 2021, the research included 10 patients, all of whom showed symptom improvement and a significant reduction in the size of the trapped ventricle, with no major complications reported during the procedure.
  • * The findings suggest that EVSP is a reliable and safer alternative to the traditional ventriculoperitoneal shunt (VPS) for treating TTH, emphasizing its potential to minimize risks associated with shunt failure and infection.
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Article Synopsis
  • The study investigated what factors contribute to better neurological outcomes in patients initially experiencing pulseless electrical activity (PEA) who received extracorporeal cardiopulmonary resuscitation (ECPR).
  • Data from the SAVE-J II registry, which included 36 hospitals in Japan, showed that only 8.2% of patients had favorable neurological outcomes, while 16.9% survived to hospital discharge.
  • Key factors linked to better outcomes included absence of cardiac rhythm conversion to asystole, presence of signs of life, pupil size, and temporary return of circulation, with certain causes of cardiac arrest like acute coronary syndrome having higher favorable outcomes.
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In patients with acute myocardial infarction (MI), heart failure (HF) is one of the most common complications that is associated with a significant burden of mortality and healthcare resources. The clinical benefits of key HF drugs, the so-called "4 pillars" or "fantastic 4", namely β-blockers, mineralocorticoid receptor antagonists, angiotensin receptor-neprilysin inhibitor, and sodium-glucose cotransporter 2 inhibitors, have been established in patients with HF with reduced ejection fraction, whereas the effects of these drugs are not comprehensively appreciated in patients with acute MI. This review summarizes current evidence on pharmacological and device-based interventions for preventing HF after acute MI.

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Objectives: Recombinant human soluble thrombomodulin (rTM) has recently been used as a promising therapeutic natural anti-coagulant drug for disseminated intravascular coagulation (DIC). Here we investigated the safety and efficacy of rTM after aortic surgery in patients with acute aortic dissection (AAD).

Methods: A total of 316 patients diagnosed with AAD underwent emergent ascending aortic replacement or total arch replacement between 2010 and 2019.

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