17 results match your criteria: "Tehran University of Medical and Health Sciences[Affiliation]"

Diagnostic and prognostic role of NLR in testicular cancer.

Explor Target Antitumor Ther

September 2024

Department of Neurosurgery, University of Florida, Gainesville, FL 32608, USA.

Article Synopsis
  • - The study investigated the neutrophil to lymphocyte ratio (NLR) and its implications in testicular cancer, finding that NLR is higher in patients than in healthy individuals or those with benign conditions.
  • - Post-surgery, specifically after orchiectomy, NLR levels significantly decrease, indicating a potential response to treatment.
  • - An elevated NLR is associated with several negative prognostic factors, such as advanced cancer stage and poorer outcomes, although it cannot distinguish between different types of testicular cancer.
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Background: Limb ischemia is a severe vascular condition that can lead to critical complications, endangering both limbs and lives. The goal of this research was to explore the role of neutrophil to lymphocyte ratio (NLR) in limb ischemia.

Methods: From inception to June 8, 2022, PubMed/MEDLINE, Institute for Scientific Information Web of Science, and Scopus were searched for articles comparing NLR in limb ischemia to healthy individuals.

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Introduction: In the current systematic review and meta-analysis, we aim to analyze the existing literature to evaluate the role of inflammatory biomarkers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), C-reactive protein (CRP), tumor necrosis factor-a (TNF-a), and interleukin-6 (IL-6) among individuals with cardiac syndrome X (CSX) compared to healthy controls.

Methods: We used PubMed, Web of Science, Scopus, Science Direct, and Embase to systematically search relevant publications published before April 2, 2023. We performed the meta-analysis using Stata 11.

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Introduction: The inflammatory response to burn injuries can lead to organ dysfunction that ultimately results in increased mortality and morbidity. This meta-analysis was conducted to determine the efficacy of inflammatory biomarkers, including the neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), procalcitonin (PCT), and C-reactive protein (CRP) as predictive tools of mortality among burn patients.

Material And Methods: The biomarker levels of survivors and non-survivors were consolidated according to guidelines for Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).

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Our study aimed to enhance understanding of nasal polyp pathophysiology by reviewing the data for variations of NLR values between patients with nasal polyp and healthy controls. We searched Web of Science, PubMed, ProQuest, and Scopus up to 2 April 2023. The search strategy was not limited to any specific language.

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Background: We conducted this systematic review to compile the evidence for the role of neutrophil to lymphocyte ratio (NLR) in odontogenic infection (OI) and to determine whether NLR is elevated in patients with OI. This was done to aid physicians in better understanding this condition for clinical management.

Methods: The search was conducted on PubMed, Scopus, and Web of Science libraries on March 30, 2023.

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Background: We conducted a systematic review and meta-analysis to compare the neutrophil lymphocyte ratio (NLR) levels between women with post-menopausal osteopenia or osteoporosis to those with normal bone mineral density (BMD).

Methods: We used Web of Science, PubMed, and Scopus to conduct a systematic search for relevant publications published before June 19, 2022, only in English language. We reported standardized mean difference (SMD) with a 95% confidence interval (CI).

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Unlabelled: One of the crucial triggers of allergic diseases is an inflammatory reaction and neutrophil to lymphocyte ratio (NLR) is one of the systemic inflammation biomarkers. Our review aimed to evaluate role of NLR in predicting severity and comorbidities of allergic rhinitis (AR). We systematically searched Scopus, Web of Science, and PubMed to find relevant studies.

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Article Synopsis
  • The study investigates the relationship between the pre-operative neutrophil to lymphocyte ratio (NLR) in gastrointestinal surgery patients and the occurrence of anastomotic leaks (AL).
  • A systematic review and meta-analysis included 12 studies with nearly 3,000 participants, revealing that those with AL had significantly higher NLR levels compared to those without.
  • Subgroup analysis indicated that while retrospective studies showed a strong correlation, prospective studies did not, and the association varied by ethnicity, being significant for white patients but not for East Asian patients.
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Background: This systematic review and meta-analysis aimed to determine the potential value of neutrophil to lymphocyte ratio (NLR) as an assessment tool in the clinical distinction between uterine sarcoma and uterine leiomyoma.

Methods: We comprehensively searched Web of Science, Scopus, and PubMed for relevant papers published before March 19, 2023. The standardized mean difference (SMD) was provided, along with a 95% confidence interval (CI).

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Article Synopsis
  • A systematic review and meta-analysis was conducted to analyze oxidative and antioxidative markers in patients with recurrent aphthous stomatitis (RAS) compared to healthy controls, including data from 30 studies.
  • Results indicated that RAS patients had significantly lower activities of certain antioxidants, like erythrocyte superoxide dismutase and glutathione peroxidase, and total antioxidant status in serum, while they exhibited increased levels of oxidative stress markers such as serum malondialdehyde.
  • Despite these differences, some antioxidant levels and vitamins (like E and C) were comparable between RAS patients and healthy individuals, suggesting ongoing oxidative stress plays a significant role in RAS pathology, though the exact causes remain unclear.
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Introduction: The neutrophil to lymphocyte ratio (NLR), an inflammatory biomarker, measures innate-adaptive immune system balance. In this systematic review and meta-analysis, we aim to analyze the current literature to evaluate the diagnostic role of NLR in neonatal sepsis.

Methods: PubMed, Web of Science, and Scopus were used to conduct a systematic search for relevant publications published before May 14, 2022.

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Background: The goal of this research was to explore the role of Neutrophil to lymphocyte ratio (NLR) in Parkinson's disease (PD).

Methods: From inception to 4 June 2023, PubMed, Web of Science, and ProQuest were searched for papers comparing NLR in PD to healthy individuals. Standardized mean difference (SMD) with a confidence interval (CI) of 95% were calculated.

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Article Synopsis
  • - The study systematically reviewed existing research to assess the diagnostic ability of the neutrophil to lymphocyte ratio (NLR) in distinguishing between tuberculosis (TB) and bacterial community-acquired pneumonia (B-CAP) using PRISMA guidelines.
  • - An analysis of data revealed that TB patients had significantly lower NLR levels compared to B-CAP patients, with consistent results found across various study quality and populations, especially in Asian cohorts.
  • - The study concluded that lower NLR levels could serve as an effective biomarker to differentiate between TB and B-CAP, with pooled sensitivity and specificity values indicating strong diagnostic potential.
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This study systematically reviewed the evidence regarding differences in the neutrophil to lymphocyte ratio (NLR) level between hypertensive and normotensive individuals as well as between patients with dipper and non-dipper hypertension (HTN). PubMed, Scopus, and Web of Science databases were systematically searched up to 20 December 2021. This was done without any limitation with regard to date, publication, or language.

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Association between the C34T polymorphism of the AMPD1 gene and essential hypertension in Malaysian patients.

Genet Mol Res

June 2016

Department of Biomedical Science, Faculty of Medicine and Heath Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.

The aim of this study was to determine whether C34T, a common polymorphism of the adenosine monophosphate deaminase 1 gene (AMPD1), is associated with essential hypertension (EH). We hypothesize that C34T is associated with the development of EH. A case-control design was used for this study.

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