20 results match your criteria: "Tehran University of Medical Sciences School of Medicine[Affiliation]"

Progression of Bone Marrow Lesions and the Development of Knee Osteoarthritis: Osteoarthritis Initiative Data.

Radiology

September 2024

From the Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 N Caroline St, JHOC 5165, Baltimore, MD 21287 (K.M., H.A.I., S.D.); Tehran University of Medical Sciences School of Medicine, Tehran, Iran (S. Mohammadi, S. Momtazmanesh); Department of Radiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Mass (F.W.R., A.G.); Department of Radiology, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (F.W.R.); West Virginia University School of Medicine, Morgantown, WV (Q.H.); Department of Rheumatology, University of Sydney, Camperdown, Australia (D.J.H.); and Royal North Shore Hospital, St. Leonards, Sydney, Australia (D.J.H.).

Article Synopsis
  • Bone marrow lesions (BMLs) are linked to an increased risk of developing knee osteoarthritis (OA), and deep learning (DL) can help in measuring BML volumes from MRI scans.
  • This study used a DL model to analyze MRI scans from a cohort of participants, categorizing their knees based on changes in BML volume over four years to assess the risk of developing knee OA.
  • Results indicated that knees with increasing BML volumes were significantly more likely to develop both radiographic and symptomatic OA compared to knees that remained BML-free or showed BML regression.
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Background: Male factor infertility can affect spermatogenesis, sexual desire, and thus the quality of life of couples. The present study was conducted to investigate the relationship between spermogram parameters, and the score of sexual desire in infertile men.

Methods: This cross-sectional study was conducted on 315 infertile men referred to the Avicenna Infertility Center of Tehran (March 2022 to March 2023).

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Unlabelled: There is presently no disease-modifying therapy for Alzheimer's Disease (AD), which is the most prevalent cause of dementia.

Objective: This study aspires to estimate the efficacy and safety of cell-based treatments in AD.

Methods: Observing the Joanna Briggs Institute (JBI) methods and Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, a systematic search was accomplished in PubMed, Medical Literature Analysis and Retrieval System Online (Medline, via Ovid), Embase; Cochrane, and Cumulative Index of Nursing and Allied Health Literature - CINAHL (via EBSCO) databases up to June 2023.

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Objective: To assess the risk of developing pulmonary tuberculosis (TB) in accordance with prior history of COVID-19 infection.

Background: Since the advent of the COVID-19 pandemic much discussion has been had on the possible role it might play on global efforts to combat TB; most, focusing on the pandemic's impact on health care systems' capabilities to manage TB cases. Mechanisms have also been proposed by which the COVID-19 infection may directly affect individuals' chance of developing TB infection.

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Ramadan fasting and type 1 diabetes: a scoping review protocol.

BMJ Open

March 2023

Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Introduction: Ramadan fasting is globally observed and a great majority of the residents of Islamic countries and elsewhere fast during Ramadan all across the world every year. Many patients with type 1 diabetes fast during Ramadan according to (or against) medical and jurisprudence advice. Nonetheless, there is a paucity of scientific evidence regarding the risks patients with diabetes who fast may be confronted with.

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Objective: Stroke is the second most prevalent cardiovascular disease in Iran. This study investigates the estimation and predictors of hospitalisation expenses and in-hospital mortality for patients who had a stroke in Iranian hospitals.

Setting: Patients who had a stroke in Iran between 2019 and 2020 were identified through the data collected from the Iran Health Insurance Organization and the Ministry of Health and Medical Education.

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Burden of Neurological Disorders Across the US From 1990-2017: A Global Burden of Disease Study.

JAMA Neurol

February 2021

Institute for Health Metrics and Evaluation, University of Washington, Seattle.

Importance: Accurate and up-to-date estimates on incidence, prevalence, mortality, and disability-adjusted life-years (burden) of neurological disorders are the backbone of evidence-based health care planning and resource allocation for these disorders. It appears that no such estimates have been reported at the state level for the US.

Objective: To present burden estimates of major neurological disorders in the US states by age and sex from 1990 to 2017.

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Background/aims: Mother-to-child transmission (MTCT) is a common transmission mode of hepatitis B virus (HBV). It has been shown that the infection may occur in some infants despite the use of immunoprophylaxis, and many studies have demonstrated the efficacy of antivirals such as lamivudine to reduce such events.

Materials And Methods: A meta-analysis was conducted concerning the efficacy and safety of lamivudine during pregnancy, in the prevention of vertical transmission of HBV infection.

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Juvenile idiopathic arthritis (JIA), the most common cause of chronic arthritis in children, is a complex immune-mediated disease with considerable long-term morbidity and mortality. According to previous studies, PTPN22 gene has been associated with JIA in several populations. In the present study, we attempted to determine the association of PTPN22 single nucleotide polymorphisms (SNPs) with susceptibility to JIA in Iranian population.

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Ghrelin is a gut hormone shown to have protective effects throughout the gastrointestinal tract. This study aims to investigate its protective effect in celiac disease induced in rats. Twenty-four rat pups were divided into 4 groups as follows: control, disease (1.

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Objectives: This study was performed to evaluate the cytotoxicity of four calcium silicate-based endodontic cements at different storage times after mixing.

Materials And Methods: Capillary tubes were filled with Biodentine (Septodont), Calcium Enriched Mixture (CEM cement, BioniqueDent), Tech Biosealer Endo (Tech Biosealer) and ProRoot MTA (Dentsply Tulsa Dental). Empty tubes and tubes containing Dycal were used as negative and positive control groups respectively.

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Background: Previous studies evaluating the relationship between serum vaspin concentrations and metabolic syndrome (MetS) have yielded contrasting results. Additionally, contribution of general and abdominal obesity, chronic inflammation, and insulin resistance to this relationship remains unknown.

Methods: In a cross-sectional setting, we investigated the association between vaspin and MetS in 145 subjects ranging from normoglycemia to type 2 diabetes.

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Evaluation of antibody response to polysaccharide vaccine and switched memory B cells in pediatric patients with inflammatory bowel disease.

Gut Liver

January 2014

Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. ; Molecular Immunology Research Center and Department of Immunology, Tehran University of Medical Sciences School of Medicine, Tehran, Iran.

Background/aims: Inflammatory bowel disease (IBD) is a chronic disease of the gastrointestinal tract, whose etiologies are still unknown. This study was performed to evaluate the humoral immune response in terms of B cell functions in selected IBD patients.

Methods: Eighteen pediatric patients with IBD, including 12 cases of ulcerative colitis (UC) and six with Crohn disease (CD), were enrolled in this study.

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Salmonella meningitis in a 16-month-old child with AIDS.

Turk J Pediatr

December 2013

Department of Pediatric Infectious Diseases, Qom University of Medical Sciences and Health Services School of Medicine, Qom, and Department of Pediatric Infectious Diseases, Tehran University of Medical Sciences School of Medicine, Tehran, Iran.

Impairment of cellular immunity related to human immunodeficiency virus (HIV) infection predisposes patients to opportunistic infections. In this report, we describe a 16-month-old boy with salmonella meningitis and acquired immunodeficiency syndrome (AIDS). The patient was referred to the Infectious Diseases Ward with a history of prolonged fever and refractory vomiting.

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Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease characterized by episodic fever and inflammatory polyserositis, which could lead to a variety of manifestations, including recurrent abdominal pain. Herein, a 12-year-old boy who has suffered from fever and bloody diarrhea since early childhood is described. All structural and underlying disorders leading to bleeding were excluded.

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Background: The facial nerve controls facial muscles and expressions. Variability in branching patterns of the nerve creates variability in facial animation, which is evident in facial plastic surgery both between patients and ethnic groups and between sides of the face. Identifying relationships between the main trunk of the facial nerve and its network of branches to soft tissues/bony fixed points contributes to safer aesthetic and reconstructive techniques.

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Objectives: To investigate the effects of morphine on reperfusion injury due to testicular torsion-detorsion (T/D).

Methods: We divided 36 adult male Sprague-Dawley rats into six groups. Testicular ischemia was achieved by twisting the right testis 720 degrees counterclockwise for 1 hour, and reperfusion was allowed for 4 hours after detorsion.

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