Expression of cytokeratin 19 in prostatic adenocarcinoma: a systematic review.

Background: Cytokeratins are intracellular proteins known as diagnostic biomarkers or prognostic factors for certain cancers. Cytokeratin 19 (CK-19) expression has been proven to have prognostic value for some cancers, but its relationship with others, such as prostate cancer (PCa), remains unclear. This systematic review article aimed to examine the relationship between CK-19 expression and prostate adenocarcinoma (PAC).

Influence of Newborns' Sex on Minor and Trace Element Concentrations in Human Milk During Early Lactation.

This study aimed to investigate the influence of newborns' sex on the concentrations of minor and trace elements in the human milk of lactating mothers during early lactation. The elemental analysis focused on calcium (Ca), potassium (K), sodium (Na), and chlorine (Cl) as minor elements and iodine (I), aluminum (Al), bromine (Br), and rubidium (Rb) as trace elements. Breast milk samples were collected from 75 lactating mothers in Tehran, Iran, during the early feeding stage.

Effects of L-carnitine supplementation on lipid profile in adult patients under hemodialysis: a systematic review and meta-analysis of RCTs.

Background: Chronic kidney disease (CKD) affects 10% of the global population and leads to end-stage renal disease (ESRD). Hemodialysis is a common treatment for ESRD, but patients often have low carnitine levels, leading to dyslipidemia, a risk factor for cardiovascular disease and the leading cause of mortality. This study aimed to assess the effects of L-carnitine on lipid profiles in adult hemodialysis patients.

Cultivating diagnostic clarity: The importance of reporting artificial intelligence confidence levels in radiologic diagnoses.

Accurate image interpretation is essential in the field of radiology to the healthcare team in order to provide optimal patient care. This article discusses the use of artificial intelligence (AI) confidence levels to enhance the accuracy and dependability of its radiological diagnoses. The current advances in AI technologies have changed how radiologists and clinicians make the diagnoses of pathological conditions such as aneurysms, hemorrhages, pneumothorax, pneumoperitoneum, and particularly fractures.

Determination of Minor and Trace Elements in Breast Milk of Lactating Mothers in Early Lactation from Tehran, Iran Using Neutron Activation Analysis Method.

This study aimed to evaluate the concentrations of both essential and non-essential elements in the breast milk of lactating mothers from Tehran, Iran, during the colostrum period. Neutron activation analysis (NAA) was used to measure the element concentrations. Additionally, the study assessed how these element concentrations were influenced by maternal factors such as age and economic status.

Long-Term Clinical and Imaging Findings in Patients with Lower Extremity Varicose Veins Treated with Endovenous Laser Treatment: A Follow-Up Study of up to 12 Years.

Introduction: This study investigates the long-term effectiveness and safety of endovenous laser treatment (EVLT) for chronic venous insufficiency (CVI), a condition commonly caused by dysfunctional valves in the venous circulation system.

Materials And Methods: In this retrospective cohort study, patients underwent EVLT and were followed up for successive short intervals and one last time after a median duration of 9-year postprocedural. Pre- and postprocedure duplex ultrasound was used to assess changes in the great saphenous vein (GSV) diameter, reflux, and saphenofemoral junction incompetence.

COVID-19 Vaccination Among Diverse Population Groups in the Northern Governorates of Iraq.

The present study was carried out to investigate COVID-19 vaccination coverage among populations of internally displaced persons (IDPs), refugees, and host communities in northern Iraq and the related underlying factors. Through a cross-sectional study conducted in five governorates in April-May 2022, 4,564 individuals were surveyed. Data were collected through an adapted questionnaire designed to gather data on participants.

Translation and validation of the Persian version of the scleroderma health assessment questionnaire (SHAQ).

The present study aimed to translate and validate the Scleroderma Health Assessment Questionnaire (SHAQ) for Persian-speaking patients (SHAQ-P), using a cross-sectional study. This cross-sectional study included SSc patients with 2013 ACR/EULAR criteria. The SHAQ was translated using a "forward-backward" method.

Recognizing intertwined patterns using a network of spiking pattern recognition platforms.

Artificial intelligence computing adapted from biology is a suitable platform for the development of intelligent machines by imitating the functional mechanisms of the nervous system in creating high-level activities such as learning, decision making and cognition in today's systems. Here, the concentration is on improvement the cognitive potential of artificial intelligence network with a bio-inspired structure. In this regard, four spiking pattern recognition platforms for recognizing digits and letters of EMNIST, patterns of YALE, and ORL datasets are proposed.

Multifunctional Gold Helix Phototheranostic Biohybrid That Enables Targeted Image-Guided Photothermal Therapy in Breast Cancer.

The preparation of multifunctional smart theranostic systems is commonly achieved through complicated strategies, limiting their biomedical applications. (SP) microalgae, as a natural helix with some of the intrinsic theranostic functionalities (e.g.

Prediction of lymphedema occurrence in patients with breast cancer using the optimized combination of ensemble learning algorithm and feature selection.

Background: Breast cancer-related lymphedema is one of the most important complications that adversely affect patients' quality of life. Lymphedema can be managed if its risk factors are known and can be modified. This study aimed to select an appropriate model to predict the risk of lymphedema and determine the factors affecting lymphedema.

Associations Between Food Insecurity and Common Mental Health Problems Among Reproductive-Aged Women in Kabul-Afghanistan.

Food insecurity has been linked to poor health outcomes, however this relationship is poorly understood among women of reproductive age. Therefore, we investigated the relationship between food insecurity and common mental health problems (CMHPs) in this population of women in Kabul, Afghanistan. A cross-sectional study was conducted with 421 women of reproductive age from four health centers located in four randomly selected zones in the city of Kabul.

Effect of Apatinib plus melatonin on vasculogenic mimicry formation by cancer stem cells from breast cancer cell line.

Background And Aim: Vasculogenic mimicry (VM) is one of the most important causes of breast cancer metastasis and resistance against drugs. The cancer stem cells (CSCs) are known as essential factors for VM formation. In this study, the effects of melatonin, Apatinib, and a combination of Apatinib/melatonin on VM formation were investigated by breast CSCs from breast cancer cell line.

Up-Regulation of in Glioblastoma Multiforme as A Regulator of and Signalling.

Objective: MicroRNAs (miRNAs) are short non-coding RNAs that play a role in post-transcriptional regulation of gene expression. was originally introduced as a regulator of genes involved in some brain tumours. Due to the high expression of in limited glioblastoma brain tumours, in this study we intend to assess the expressions of and in brain tumour tissues and attribute new target genes to these miRNAs.

Psychometric properties of dexterity questionnaire-24 in Iranian chronic stroke survivors.

Introduction: Dexterity is one of the most critical upper extremity functions that may be impaired in chronic stroke survivors. This study aimed to investigate the psychometric properties of DextQ-24 in Iranian chronic stroke survivors.

Method: A total of 123 people with chronic stroke were included in the study.

The inverse association of body adiposity index and bone health in the older adults: A report from a developing country.

The ageing process influences body composition and could be related to bone health. The current study was set out to evaluate the association between body adiposity index (BAI) and bone health in older adults. This is a cross-sectional study performed on 178 elderly persons (51 men and 127 women) with a mean age of 67.

Exposure to ambient air pollution and socio-economic status on intelligence quotient among schoolchildren in a developing country.

Evidence suggests the association between ambient airborne particulate matters and children's IQ and psychological development in the early stages of life. However, data on the relationship between ambient air particulate matters and children's IQ are rare in developing countries and less privileged areas. In this study, the association between PM and PM and the IQ of children in different areas were investigated in terms of pollution levels.

Rapid Assessment of COVID-19 Screening Program for Travelers in Iran: A Qualitative Study.

Objective: Coronavirus disease 2019 (COVID-19) screening stations set up by Iranian Red Crescent Society have been available for 17 d with the aim of identifying and treating people with coronavirus, reducing road trips, and sensitizing people to the problem. This study aims to investigate the challenges of the procedure.

Methods: A qualitative study was used to find the challenges of the COVID-19 screening centers.

Ocular safety of repeated intravitreal injections of Carboplatin and Digoxin: A preclinical study on the healthy rabbits.

To evaluate the ocular safety of intravitreal carboplatin and digoxin injections as a new intravitreal chemotherapy option for retinoblastoma tumor vitreous seeds. Eighteen rabbits were divided randomly into three groups to receive intravitreal injection of Digoxin (6 rabbits), Carboplatin (7 rabbits), or Saline (5 rabbits). In every group, one eye randomly treated with 10 µg Digoxin in 0.

Potential Therapeutic Effects of Melatonin Mediate via miRNAs in Cancer.

miRNAs are evolutionarily conserved non-coding ribonucleic acids with a length of between 19 and 25 nucleotides. Because of their ability to regulate gene expression, miRNAs have an important function in the controlling of various biological processes, such as cell cycle, differentiation, proliferation, and apoptosis. Owing to the long-standing regulative potential of miRNAs in tumor-suppressive pathways, scholars have recently paid closer attention to the expression profile of miRNAs in various types of cancer.

Repurposing metformin for covid-19 complications in patients with type 2 diabetes and insulin resistance.

Understanding the exact role of current drugs in Covid-19 disease is essential in the era of global pandemics. Metformin which prescribed as the first-line treatment of type 2 diabetes has beneficial effects on Sars-cov2 infection. These effects are including regulation of immune system, Renin-Angiotensin System and Dipeptidyl Peptidase 4 function in Covid-19 infection.

CAG repeats and one polymorphism in androgen receptor gene are associated with renal calcium stone disease.

Purpose: Evidence suggests that androgens can be involved in the pathogenesis of renal stones. This study aimed at investigating coding region polymorphisms and CAG repeats in androgen receptor (AR) and their association with active renal calcium stone disease.

Materials And Methods: Male patients with calcium kidney stones ( = 106) with at least two episodes of stone recurrence or size increase during the past 5 years (ASF) were enrolled from December 2008 to April 2009.