1,493 results match your criteria: "Tehran Heart Center[Affiliation]"

Three-dimensional gradient-echo (3D-GRE) sequences provide isotropic or nearly isotropic 3D images, leading to better visualization of smaller structures, compared to two-dimensional (2D) sequences. The aim of this study was to prospectively compare 2D and 3D-GRE sequences in terms of key imaging metrics, including signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), glenohumeral joint space, image quality, artifacts, and acquisition time in shoulder joint images, using 1.5-T MRI scanner.

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  • The meta-analysis compares long-term outcomes of transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in low-surgical risk patients with severe aortic stenosis.
  • TAVR showed lower all-cause mortality risk within 30 days and up to one year compared to SAVR, but risks were similar after one year.
  • Additionally, TAVR had lower rates of cardiovascular mortality, disabling strokes, rehospitalizations, and new-onset atrial fibrillation, but a higher chance of needing a permanent pacemaker, especially in the first 30 days.
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Current data evaluating outcomes of valve replacement surgery in patients with overweight/obesity is contradictory. There is a scarce study comparing outcomes of valve surgery considering the type of valve involved in the procedure. We followed outcomes in patients with overweight and obesity after valve replacement surgery with or without coronary artery bypass graft (CABG) and also patients with aortic valve replacement (AVR) and mitral valve replacement (MVR), separately to compare their mid-term prognosis in each group.

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  • The study investigated ECG abnormalities related to cardiac channelopathies linked to sudden cardiac death among adults in Tehran, Iran, highlighting their under-recognition in the region.
  • Out of 7,350 analyzed ECGs, long QT intervals were the most common abnormality found at 3.08%, with several factors influencing their prevalence, such as age and lifestyle choices.
  • Overall, those with abnormal ECG patterns had a significantly higher all-cause mortality rate (6.3%) compared to those without such patterns (2.96%), indicating potential health risks.
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Background: Medullary thyroid cancer (MTC) is one of the rare neuroendocrine malignancies. This cancer is hereditary in approximately 20% of cases. Although lymph node (LN) metastasis is prevalent in MTC, distant metastasis is not commonly seen in these patients.

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  • - The study investigates the effectiveness and safety of dual antiplatelet therapy (DAPT) in high bleeding risk (HBR) patients, focusing on how these factors are influenced by DAPT duration and different stent types.
  • - A network meta-analysis of 13 randomized controlled trials involving nearly 19,500 HBR patients found that short DAPT with durable polymer drug-eluting stents (DP-DES) is associated with lower bleeding risks while still maintaining efficacy compared to standard DAPT.
  • - The research concludes that for HBR patients undergoing coronary interventions, using a short DAPT strategy with DP-DES strikes the best balance between minimizing bleeding risks and preventing adverse cardiovascular events.
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Coronary artery bypass grafting in octogenarians: a nomogram for predicting all-cause mortality.

J Cardiothorac Surg

October 2024

Research Center for Advanced Technologies in Cardiovascular Medicine, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Background: The benefits and risks of coronary artery bypass grafting (CABG) in octogenarians remain unclear. This study aimed to identify the predictors of increased risk of all-cause mortality in octogenarian patients after CABG.

Methods: We retrospectively analyzed the data of 1636 octogenarians who underwent isolated elective on-pump CABG between 2007 and 2016.

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Background: Peripheral artery disease (PAD) is a common disease associated with atherosclerosis, leading to significant mortality and morbidity worldwide. Our study focuses on the association between insulin resistance (IR) and PAD, specifically investigating the triglyceride-glucose index (TyG) as a potential surrogate marker of IR in the context of PAD by pooling the existing studies on this topic.

Methods: Online databases, including PubMed, Embase, Scopus, and the Web of Science, were searched to find the studies comparing the TyG index in PAD vs.

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  • The Triglyceride-glucose index (TyG) serves as a marker for insulin resistance and may predict the risk of major adverse cardiac and cerebrovascular events (MACCE) in patients with acute coronary syndromes (ACS) undergoing percutaneous coronary intervention (PCI).
  • A study involving 13,542 patients showed that higher TyG levels, particularly in the fourth quartile, significantly correlated with an increased risk of MACCE, such as heart attacks and strokes.
  • In contrast, no significant association was found between TyG levels and MACCE in a subgroup of patients who were euglycemic, suggesting the need for further studies to confirm these findings for better clinical risk assessment.
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  • Researchers studied strokes from 1990 to 2021 to understand how many people get them and how they are affected around the world.
  • In 2021, strokes caused about 7.3 million deaths and were a major cause of health problems, especially in specific regions like Southeast Asia and Oceania.
  • There are differences in stroke risks based on where people live and their age, and some areas actually saw more strokes happening since 2015.
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Introduction: Coronary cameral fistulas (CCFs) are rare congenital anomalies characterized by abnormal connections between a coronary artery and one of the cardiac chambers. These abnormal connections can lead to significant clinical implications, including heart failure and myocardial ischemia, necessitating timely diagnosis and intervention.

Case Presentation: A 5-year-old Iranian boy was brought to the emergency room at Heart Hospital Center complaining of chest pain and dyspnea on exertion.

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This case report explores the left atrial mitral valve cord, an extremely rare congenital anomaly. Typically involving mitral valve leaflets and associated with mild mitral regurgitation, it is rarely documented independently. A 51-year-old patient presented with dizziness, and diagnostic challenges arose during transthoracic echocardiography (TTE).

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Background: The latest guidelines advocate for catheter ablation (CA) over standard medical therapy (SMT) for managing atrial fibrillation (AF) in patients with heart failure with reduced ejection fraction (HFrEF). However, significant knowledge gaps exist regarding the effectiveness of CA vs. SMT in patients with heart failure with preserved ejection fraction (HFpEF).

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  • Early-life exposure to famine is linked to a higher risk of osteoporosis, fractures, and decreased bone mineral density (BMD) in later life, indicating significant long-term health impacts.
  • A systematic review and meta-analysis of 10 studies revealed that individuals exposed to famine during critical developmental periods had greater odds of developing osteoporosis (2.12 times) and experiencing fractures (1.58 times) compared to those not exposed.
  • Key findings suggest that exposure during fetal and childhood stages has particularly strong associations with poor bone health outcomes, highlighting the importance of early nutrition and health interventions.
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Background & Aim: Timely identification of the patients requiring intensive care unit admission (ICU) could be life-saving. We aimed to compare different machine learning algorithms to predict the requirements for ICU admission in COVID-19 patients.

Methods: We screened all patients with COVID-19 at six academic hospitals in Tehran comprising our study population.

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We aimed to assess the diagnostic performance of Cardiac Magnetic Resonance (CMR) strain parameters in ACM patients to evaluate their diagnostic role. We systematically searched MEDLINE, EMBASE, Scopus, and Web of Science. Of the 146 records, 16 were included.

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  • * A study from 1990 to 2019 revealed around 339,000 patients with AF/AFL in Iran, with 30,200 new cases and significant disability-adjusted life years (DALYs) lost, largely due to high blood pressure and body mass index.
  • * Projections for 2050 indicate the number of AF/AFL patients could reach 1.1 million, emphasizing the need for improved prevention strategies targeting risk factors, despite advancements in treatment.
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Background: Percutaneous pulmonary valve implantation (PPVI) is a recognized alternative treatment to surgery for patients with dysfunctional right ventricular outflow tracts. Patient selection is essential to avoid serious complications from attempted treatment, such as rupture or dissection, especially of the calcified outflow tracts. We describe a case with an unexpected rupture of a calcified homograft valve and main pulmonary artery, which was treated successfully by emergency implantation of a self-expanding Venus P-Valve (Venus MedTech, Hangzhou, China) without the need for pre-stenting with a covered stent.

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Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women. Dyslipidemia is a prevalent metabolic abnormality in individuals with PCOS. Moreover, vitamin D deficiency is widespread across all societal strata, with a particularly heightened prevalence observed in patients afflicted with PCOS.

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Association of new onset seizure and COVID-19 vaccines and long-term follow-up: A systematic review and meta-analysis.

Epilepsia

October 2024

Departments of Neurology, Epidemiology, and Neurosurgery and the Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.

Article Synopsis
  • Seizures have been observed as a potential side effect of COVID-19 vaccines, but existing studies show no solid evidence indicating an increased risk compared to the general population.
  • A systematic review analyzed data from various databases, including PubMed and Cochrane Library, to compare seizure occurrences in vaccinated individuals versus unvaccinated controls, employing rigorous research standards.
  • The findings revealed no significant difference in the incidence of new seizures between COVID-19 vaccine recipients and unvaccinated individuals, suggesting that vaccination does not elevate the risk of seizures.
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Background: An abnormal variation in blood electrolytes, such as potassium, contributes to mortality in children admitted to intensive care units. Continuous and real-time monitoring of potassium serum levels can prevent fatal arrhythmias, but this is not currently practical. The study aims to use machine learning to estimate blood potassium levels with accuracy in real time noninvasively.

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Introduction: Iatrogenic femoral artery pseudoaneurysm (FAP) is a complication following femoral artery puncture, with an incidence rate of 0.2%-5.5% post-cardiac catheterization procedures.

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  • CAR T-cell therapy is an innovative treatment for certain blood cancers, but it's linked to serious cardiovascular events (CVE), including arrhythmias and heart failure.
  • A systematic review analyzed 23 studies, revealing that over half of patients experienced CVEs, particularly those with severe cytokine release syndrome (CRS).
  • The findings emphasize the need for close monitoring and personalized care to address potential cardiotoxic effects, while also noting that cardiac mortality rates appear to be low, indicating room for improvement in prevention strategies.
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Background: Cleft in the mitral valve leaflet is a primary cause of congenital mitral regurgitation, stemming from developmental anomalies in the mitral valve and frequently associated with other congenital heart defects. Concurrent presence of cleft in mitral valve leaflet with atrial septal defect and ventricular septal defect is relatively rare. Echocardiography, especially transesophageal echocardiography, is essential in diagnosing cleft mitral valve leaflet and related congenital heart defects, providing critical, detailed imagery for accurate assessment.

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