Efficacy and safety of omalizumab in paediatric age: an update of literature data.

Immunoglobulin E (IgE) was discovered in 1966 and was found responsible for immune defense against helminths, type I hypersensitivity and allergic diseases. IgE mediates allergic responses by binding to Fc receptors (the high affinity Fc-epsilon receptor I and the low affinity Fc-epsilon receptor II or CD23) expressed on tissue mast cells and blood basophils. This binding leads to degranulation and release of pro-inflammatory mediators.

The Application of Virtual Planning and Navigation Devices for Mandible Reconstruction and Immediate Dental Implantation.

Routine reconstruction of subtotal defects of the mandible and orthopedic rehabilitation supported by dental implants is achieved by means of detailed planning and lasts over a year. This article shows the outcomes of single-stage surgical treatment and immediate orthopedic rehabilitation performed with the help of preoperative virtual computer simulation. 3D investigation of pathological and donor sites, virtual simulation of tumor resection, positioning of the dental implants into fibula, virtual flap bending and transfer, virtual bending of fixing reconstruction plates, and fabrication of navigation templates and bridge prosthesis supported by dental implants were done preoperatively.

Pericardial sewing-cuff: an alternative surgical technique for full-root implantation of aortic allograft and pulmonary autograft.

The following is a description of a modified technique for the reinforcement of proximal anastomosis regarding the process of aortic allograft or pulmonary autograft full root implantation. A double width pericardial strip is used to create a pericardial sewing-cuff to be used as a neo-ring. This technique is said to be best suited for decreasing the operative bleeding, reducing anastomotic pitfalls and concomitant repair of the aortic annulus.

Community-based nutritional intervention for reducing malnutrition among children under 5 years of age in the Islamic Republic of Iran.

A project was conducted in a rural area in September 1994 with the aim of decreasing the incidence of protein-energy malnutrition among children under 5 years, by nutritional intervention through the primary health care system. An initial situation analysis revealed the region's resources and causes of malnutrition. Practical instruction on feeding methods, deworming, environmental sanitation, the promotion of home-grown vegetables and reinforcement of the growth monitoring programme were chosen as the routes for intervention.