Hydration dynamics of collagen in aqueous buffer solution as studied by time domain dielectric spectroscopy.

Dielectric relaxation studies of collagen in aqueous buffer solution (pH 3.7) have been carried out at four different temperatures 283, 288, 293 and 298 K as a function of collagen concentration between 0.033 μM and 0.

Serum responsive proteome reveals correlation between oxidative phosphorylation and morphogenesis in Candida albicans ATCC10231.

Unlabelled: To understand the impact of fetal bovine serum (FBS) on metabolism and cellular architecture in addition to morphogenesis, we have identified FBS responsive proteome of Candida albicans. FBS induced 34% hyphae and 60% pseudohyphae in C. albicans at 30 °C while 98% hyphae at 37 °C.

Anti-biofilm Activity Against Gram-Positive Bacteria by Biologically Synthesized Silver Nanoparticles Using Curcuma longa.

Objective: To assess the biofilm inhibition activity of biosynthesized silver nanoparticles (AgNPs) using Curcuma longa.

Method: Characterizations of these biogenic nanoparticles were done by UV-Vis spectroscopy, TEM, EDX and nanoparticles tracking analyzer. The antibiofilm activity of AgNPs against S.

Bioactive mushroom polysaccharides as antitumor: an overview.

Immuno-therapies are gaining more importance to treat certain forms of cancer. The goal of therapies is to enhance person's own IgG, IgA, IgM, IgD, IgE and macrophages to combat with neoplastic cells hence the effectiveness of the immune system. Since, early civilization mushrooms are considered as potent food as well as medicine.

Microenvironment Responsive Modulations in the Fatty Acid Content, Cell Surface Hydrophobicity, and Adhesion of Candida albicans Cells.

Considering the significance in survival and virulence, we have made an attempt to understand modulations in the membrane and cell wall properties of Candida albicans hyphae induced by temperature (37 °C) and neutral pH and yeast form cells grown under low hydrostatic pressure (LHP). Our results suggest that cell surface hydrophobicity (CSH) and adhesion are dynamic properties determined largely by the microenvironment rather than morphological forms, citing the significance of variation in niche specific virulence. GC-MS analysis showed that 49 and 41 fatty acids modulated under hyphal form induced by temperature alone (37 °C) and neutral pH, respectively while that of 58 under yeast form cells under low hydrostatic pressure (LHP) (1800 Pa).

Limonene inhibits Candida albicans growth by inducing apoptosis.

Anti-Candida potential of limonene was evaluated against planktonic growth, biofilm (adhesion, development and maturation) and morphogenesis of Candida albicans in this study. Limonene is a major constituent of citrus oil and most frequently used terpene in food and beverage industry due to its pleasant fragrance, nontoxic, and is generally recognized as safe (GRAS) flavoring agent as well as treatment option in many gastrointestinal diseases.Limonene exhibited excellent anti-Candida activity and was equally effective against planktonic growth of C.

Phytochemical profile, aldose reductase inhibitory, and antioxidant activities of Indian traditional medicinal (L.) fruit extract.

(L.) fruits (CGFs) are commonly used for culinary purposes and has several therapeutic applications in the Southeast Asia. The aim of this work was to evaluate phytochemical profile, aldose reductase inhibitory (ARI), and antioxidant activities of CGF extract.

16S ribosomal RNA sequencing and molecular serotyping of isolated from Indian field conditions.

Aim: This study was aimed at identifying Indian field isolates of on both molecular as well as serological levels that cause infectious coryza in chickens.

Materials And Methods: Species-specific polymerase chain reaction (HPG-2 PCR), and 16S ribosomal RNA (rRNA) sequencing were employed for molecular identification. Whereas, multiplex PCR technique was used for serological identification of Indian field isolates of .

Morphotypes and pigment profiles of halophilic bacteria: Practical data useful for novelty, taxonomic categorization and for describing novel species or new taxa.

Halophilic bacteria were isolated from oil spill samples collected from West-coast of Goa. Bacteria were isolated from oil studded soil, salt marsh and offshore samples (A, A7, CSM, CB and CM) collected along the West coastline in Goa (India) i.e.

Pharmacophore Mapping Approach for Drug Target Identification: A Chemical Synthesis and in Silico Study on Novel Thiadiazole Compounds.

Introduction: Compounds containing thiadiazole moiety are cognized to possess with variety of clinical and therapeutic activity. Finding a suitable drug target for newly synthesized compounds remain a major bottle neck in current high throughout medicinal chemistry era.

Aim: To effectively synthesize di substituted thiadiazole compounds and demonstrate drug target identification using an in silico pharmacophore probing approach.

The structural and magnetic properties of dual phase cobalt ferrite.

The bismuth (Bi)-doped cobalt ferrite nanostructures with dual phase, i.e. cubic spinel with space group Fd3m and perovskite with space group R3c, have been successfully engineered via self-ignited sol-gel combustion route.

and cardiovascular complications: a mechanism based review on role of in cardiovascular diseases.

Heart disease comprises a wide class of cardiovascular abnormalities, including ischemic heart disease, myocardial infarction, atherosclerosis, and coronary artery disease. It is the leading cause of death all over the world. Several traditional and novel risk factors, such as infectious and noninfectious agents, have been associated with heart disease.

Response of extreme haloarchaeon Haloarcula argentinensis RR10 to simulated microgravity in clinorotation.

Gravity is the fundamental force that may have operated during the evolution of life on Earth. It is thus important to understand as to what the effects of gravity are on cellular life. The studies related to effect of microgravity on cells may provide greater insights in understanding of how the physical force of gravity shaped life on Earth.

Data on graphical representation (CGR and FCGR) of bacterial and archaeal species from two Soda Lakes.

In this paper, we presented the datasets generated using Chose Game representation (CGR) and Choase Game Representation of Frequencies (FCGR) of bacterial and archaeal 16S rRNA sequences. The data in the form of graphical representations was yielded with the help of ENDMEMO tool. The computational representation of these data datasets is useful for studies and interpretation of microbial sequences.

Molecular interactions in ethyl acetate-chlorobenzene binary solution: Dielectric, spectroscopic studies and quantum chemical calculations.

Dielectric studies using Time Domain Reflectometry method has been carried out on the binary solution of Ethyl acetate (EA) with Chlorobenzene (CBZ) over the entire composition range. Spectroscopic (FTIR and C NMR) signatures of neat EA, CBZ and their equimolar binary solution have also been recorded. The results of the spectroscopic studies favour the presence of (CBZ) CH⋯OC (EA), (EA) methylene CH⋯π electrons (CBZ) and (EA) methyl CH⋯Cl (CBZ) contacts which have been validated using quantum chemical calculations.

Inhibition of glycation and aldose reductase activity using dietary flavonoids: A lens organ culture studies.

On the eve of increasing incidence of diabetes mellitus and related complications, the search for novel, safe and alternatives therapeutic approaches are evolving. In the present investigation, a panel of ten dietary flavonoids such as 4'-methoxyflavanone, formononetin, hesperetin, hesperidin, naringenin, naringin, rutin, diadzin, silibinin and silymarin was evaluated as possible inhibitors of sugar induced cataractogenesis using bovine lens organ culture studies. The effect of selected flavonoids was observed on glycation induced lens opacity, AGE fluorescence, carbonyl group formation (a biomarker of glycation), protein aggregation and aldose reductase (AR) inhibition.

Voyage of theranostic liposomes for imaging and therapy.

Drug delivery is a critical issue in any disease treatment. Nowadays much more effort is being focused on integrating imaging agent and therapeutic drugs in a single formulation to achieve a simultaneous disease diagnosis and targeted drug delivery. This new terminology 'nanotheranostics' have been used to describe these nanoparticle formulations.

Large, Linear, and Tunable Positive Magnetoresistance of Mechanically Stable Graphene Foam-Toward High-Performance Magnetic Field Sensors.

Here, we present the first observation of magneto-transport properties of graphene foam (GF) composed of a few layers in a wide temperature range of 2-300 K. Large room-temperature linear positive magnetoresistance (PMR ≈ 171% at B ≈ 9 T) has been detected. The largest PMR (∼213%) has been achieved at 2 K under a magnetic field of 9 T, which can be tuned by the addition of poly(methyl methacrylate) to the porous structure of the foam.

In silico PASS analysis and determination of antimycobacterial, antifungal, and antioxidant efficacies of maslinic acid in an extract rich in pentacyclic triterpenoids.

Objective/background: Microbial infections such as tuberculosis is a major cause of mortality worldwide. Plant-derived phytochemicals have a long history of providing much-needed novel therapeutics. Triterpenoids are among the prominent phytochemicals that possess numerous biological activities.

Genomic Analysis of a Marine Bacterium: Bioinformatics for Comparison, Evaluation, and Interpretation of DNA Sequences.

A total of five highly related strains of an unidentified marine bacterium were analyzed through their short genome sequences (AM260709-AM260713). Genome-to-Genome Distance (GGDC) showed high similarity to (X67024). The generated unique Quick Response (QR) codes indicated no identity to other microbial species or gene sequences.

Luminescent Ruthenium(II) Polypyridyl Complexes as Nonviral Carriers for DNA Delivery.

Two new luminescent ruthenium(II) polypyridyl complexes, [Ru(bpy) (tpt-phen)]Cl (1; bpy=2,2'-bipyridine, tpt-phen=triptycenyl-1,10-phenanthroline) and [Ru(phen) (tpt-phen)]Cl (2; phen=1,10-phenanthroline), have been developed as potential nonviral vectors for DNA delivery. Photophysical and electrochemical properties of the complexes have been investigated and corroborated with electronic structure calculations. DNA condensation by these complexes has been investigated by UV/Vis and emission spectroscopy, circular dichroism spectroscopy, atomic force microscopy, dynamic light scattering, confocal microscopy, and electrophoretic mobility studies.

Electrochemical synthesis and potential electrochemical energy storage performance of nodule-type polyaniline.

Nodule-type polyaniline (PAni) has been successfully electrosynthesized onto conducting substrate and envisaged in electrochemical supercapacitor (ES) application as a potential energy storage electrode. Various bands are confirmed from the X-ray photoelectron and Fourier transform infrared spectra. Each nodule is of ∼100-200nminlength and 20-80nmindiameter.

Is the increase in oil pollution a possibility of the presence of diverse microorganisms? An experimental dataset on oil prevalent areas of Goa, India.

Survey data and wet lab reports presented in this paper were collected from Western coastlines of India from Goan beaches. Oil polluted areas were captured on camera as evidence for oil and tar pollution. Several microorganisms showing diverse characteristics such as pigment producers, salt tolerant and hydrocarbon resistance were isolated and cultured in the laboratory.

Botanical identification of plants described in Mādhava Cikitsā for the treatment of diarrhoea.

Context: Mādhava is regarded as a 7(th) century Indian Physician who composed two treatises (in Sanskrit) on Ayurveda, the Mādhava Nidāna and Mādhava Cikitsā. The former treatise deals with the diagnosis of diseases while the latter with the treatment using medicinal plants and other recipes. In Mādhava Cikitsā, a common Sanskrit name is found to describe two or more totally different botanical plant species (thus leading to ambiguity) and a distinct botanical species is also found to represent two or more Sanskrit names at several instances.

Relaxation dynamics and thermophysical properties of vegetable oils using time-domain reflectometry.

Dielectric relaxation studies of vegetable oils are important for insights into their hydrogen bonding and intermolecular dynamics. The dielectric relaxation and thermo physical properties of triglycerides present in some vegetable oils have been measured over the frequency range of 10 MHz to 7 GHz in the temperature region 25 to 10 °C using a time-domain reflectometry approach. The frequency and temperature dependence of dielectric constants and dielectric loss factors were determined for coconut, peanut, soya bean, sunflower, palm, and olive oils.