Ionic Remote α-C-H Allenylation of Silyl Ethers Involving a [1,5]-Hydride Shift Promoted by Silylium-Ion Regeneration.

A silylium-ion-promoted α-C-H allenylation of silyl ethers tethered to an internal alkyne is described. The actual intermolecular allenylation event occurs after the -selective hydrosilylation of the alkyne, where an in situ-generated β-silicon-stabilized vinyl cation engages in an intramolecular [1,5]-hydride shift. This process transforms the silyl ether into a silylcarboxonium ion, which reacts with propargylsilanes as nucleophiles, formed by the rapid silylium-ion-catalyzed isomerization of allenylsilanes.

An artificial insurance framework for a hydrogen-based microgrid to detect the advanced cyberattack model.

Microgrid systems have evolved based on renewable energies including wind, solar, and hydrogen to make the satisfaction of loads far from the main grid more flexible and controllable using both island- and grid-connected modes. Albeit microgrids can gain beneficial results in cost and energy schedules once operating in grid-connected mode, such systems are vulnerable to malicious attacks from the viewpoint of cybersecurity. With this in mind, this paper explores a novel advanced attack model named the false transferred data injection (FTDI) attack aiming to manipulatively alter the power flowing from the microgrid to the upstream grid to raise voltage usability probability.

Anhedonia relates to reduced striatal reward anticipation in depression but not in schizophrenia or bipolar disorder: A transdiagnostic study.

Anhedonia, i.e., the loss of pleasure or lack of reactivity to reward, is a core symptom of major psychiatric conditions.

Comparison of laparoscopic performance using low-cost laparoscopy simulators versus state-of-the-art simulators: a multi-center prospective, randomized crossover trial.

Introduction: Simulator training is an efficient method for the development of basic laparoscopic skills. We aimed to investigate if low-cost simulators are comparable to more expensive box trainers regarding surgeons usability, likability, and performance.

Methods: This multi-center, randomized crossover study included 16 medical students, seven abdominal surgeons, and seven urological surgeons.

Treatment of mandibular condyle fractures with a rhombic 3D condylar fracture plate - Does the surgical approach matter?

Fractures involving the mandibular condyle are a significant subset of mandibular fractures, demanding specialized implant design considerations for effective surgical treatment. The core objective of this study was to assess the clinical and radiographic results in patients treated with a single rhombic-shaped implant according to the surgical approach used. This retrospective cohort investigation, spanning a ten-year recruitment window, included individuals with unilateral fractures who underwent surgical treatment with a rhombic-shaped implant.

Surrogate End Points for Overall Survival in Neoadjuvant Randomized Clinical Trials for Early Breast Cancer.

Purpose: To assess trial-level surrogacy value for overall survival (OS) of the pathologic complete response (pCR) and invasive disease-free survival (iDFS) in randomized clinical trials (RCTs) for early breast cancer (BC).

Methods: Individual patient data of neoadjuvant RCTs with available data on pCR, iDFS, and OS were included in the analysis. We used the coefficient of determination from weighted linear regression models to quantify the association between treatment effects on OS and on the surrogate end points.

Systemic venous collaterals between Glenn and Fontan: prevalence, therapy, and impact on outcomes.

Objective: This study aimed to evaluate veno-venous collaterals between bidirectional cavopulmonary shunt and total cavopulmonary connection.

Methods: Patients who underwent staged total cavopulmonary connection between 1995 and 2022 were reviewed. Veno-venous collaterals between bidirectional cavopulmonary shunt and total cavopulmonary connection were depicted using angiograms.

Spin-orbit interaction driven terahertz nonlinear dynamics in transition metals.

The interplay of electronic charge, spin, and orbital currents, coherently driven by picosecond long oscillations of light fields in spin-orbit coupled systems, is the foundation of emerging terahertz lightwave spintronics and orbitronics. The essential rules for how terahertz fields interact with these systems in a nonlinear way are still not understood. In this work, we demonstrate a universally applicable electronic nonlinearity originating from spin-orbit interactions in conducting materials, wherein the interplay of light-induced spin and orbital textures manifests.

Stable Operation of Copper-Protected La(FeMnSi)H Regenerators in a Magnetic Cooling Unit.

Magnetic refrigeration leads the current commercialization efforts of ambient caloric cooling technologies, is considered among its peers most promising in terms of anticipated energy efficiency gain, and allows for complete elimination of harmful coolants. By now, functional magnetocaloric components (so-called regenerators) based on Mn-substituted and hydrogenated LaFeSi alloys are commercially available. However, this alloy system exhibits magnetostriction, is susceptible to fracture, oxidation, and does not passivate well, rendering it prone to failure and corrosion, particularly when using water as favorable heat exchange medium.

The mind, brain, and body study: A protocol for examining the effects of the gut-brain-immune axis on internalizing symptoms in youth exposed to caregiving-related early adversity.

Experiences of caregiving-related adversity are common and one of the strongest predictors of internalizing psychopathology (i.e., anxiety and depression).

Prominosomes - a particular class of extracellular vesicles containing prominin-1/CD133?

Extracellular membrane vesicles (EVs) offer promising values in various medical fields, e.g., as biomarkers in liquid biopsies or as native (or bioengineered) biological nanocarriers in tissue engineering, regenerative medicine and cancer therapy.

Signal theory based encryption of faster-than-Nyquist signals for fiber and wireless transmission.

New applications such as the Internet of Things, autonomous driving, Industry X.0 and many more will transmit sensitive information via fibers and over the air with envisioned data rates beyond terabits per second. Therefore, the encryption has to be simple, fast and spectrally efficient, so that the power consumption and latency are low and the scarce bandwidth is not wasted.

2D wrinkle assisted zigzag plasmonic chains for isotropic SERS enhancement.

Template-assisted colloidal self-assembly has gained significant attention due to its flexibility and versatility. By precisely controlling the shape of the template, it is possible to achieve custom-designed nanoparticle assemblies. However, a major challenge remains in fabricating these templates over large areas at a low cost.

Simultaneous Unbinned Differential Cross-Section Measurement of Twenty-Four Z+jets Kinematic Observables with the ATLAS Detector.

Z boson events at the Large Hadron Collider can be selected with high purity and are sensitive to a diverse range of QCD phenomena. As a result, these events are often used to probe the nature of the strong force, improve Monte Carlo event generators, and search for deviations from standard model predictions. All previous measurements of Z boson production characterize the event properties using a small number of observables and present the results as differential cross sections in predetermined bins.

Measurement of Λ_{b}^{0}, Λ_{c}^{+}, and Λ Decay Parameters Using Λ_{b}^{0}→Λ_{c}^{+}h^{-} Decays.

A comprehensive study of the angular distributions in the bottom-baryon decays Λ_{b}^{0}→Λ_{c}^{+}h^{-}(h=π,K), followed by Λ_{c}^{+}→Λh^{+} with Λ→pπ^{-} or Λ_{c}^{+}→pK_{S}^{0} decays, is performed using a data sample of proton-proton collisions corresponding to an integrated luminosity of 9  fb^{-1} collected by the LHCb experiment at center-of-mass energies of 7, 8, and 13 TeV. The decay parameters and the associated charge-parity (CP) asymmetries are measured, with no significant CP violation observed. For the first time, the Λ_{b}^{0}→Λ_{c}^{+}h^{-} decay parameters are measured.

Determination of Reactive Dyes in Coloring Foodstuff, Fruit Juice Concentrates, and Meat Products by Reductive Azo-Bond Cleavage and LC-ESI-MS/MS Analysis.

Visually appealing foods are often associated by consumers with subjective quality features, such as freshness, palatability, and shelf life. In the past, there have been repeated violations in which regulations on the use of pigments in food were ignored and/or unauthorized or toxic dyes (e.g.

Reimbursement policies of Swiss health insurances for the surgical treatment of symptomatic breast hypertrophy: a retrospective cohort study.

Background: Patients with symptomatic breast hypertrophy typically suffer from chronic back pain, recurrent skin irritation at the inframammary fold and/or low self-esteem resulting in impaired quality of life. Reduction mammaplasty has been shown to effectively treat symptomatic breast hypertrophy with high patient satisfaction. Despite the obvious benefits, reimbursement requests for reduction mammaplasty are initially often refused by the patient's health insurance company, thereby frequently resulting in additional examinations and eventually extra expenses.

Toward climate neutral data centers: Greenhouse gas inventory, scenarios, and strategies.

The climate impact of data centers is expected to increase due to rising demand for information and communication technology services. At the same time, the European Union aims for climate neutral data centers by 2030. To map potential developments of emissions associated with data centers to the year 2030, we develop a generic data center greenhouse gas (GHG) inventory in accordance with the GHG protocol.

Clinical Presentation and Course of Pulmonary Involvement in Chronic Nonbacterial Osteomyelitis.

Objective: Pulmonary involvement in chronic nonbacterial osteomyelitis (CNO) is rare. Limited awareness results in diagnostic challenges, especially because malignancy or infection needs to be considered.

Methods: Based on a survey shared among centers participating in the Kerndokumentation Deutsches Rheumaforschungszentrum (Germany), this study investigated clinical and imaging presentations, demographic features, treatment response and outcomes of pulmonary involvement in CNO (pCNO).

Factors influencing role preferences in decision-making of healthy women with BRCA1/2 pathogenic variants: subanalysis from a randomised controlled decision coaching trial.

Background: Patients who actively engage in their medical decision-making processes can experience better health outcomes. This exploratory study aimed to identify predictors of preferred and actual roles in decision-making in healthy women with BRCA1/2 pathogenic variants (PVs).

Methods: Women with BRCA1/2 PVs without a history of breast and/or ovarian cancer were recruited in six centres across Germany.

Chromosome-scale genome assembly reveals how repeat elements shape non-coding RNA landscapes active during newt limb regeneration.

Newts have large genomes harboring many repeat elements. How these elements shape the genome and relate to newts' unique regeneration ability remains unknown. We present here the chromosome-scale assembly of the 20.

A Digital Tool (Technology-Assisted Problem Management Plus) for Lay Health Workers to Address Common Mental Health Disorders: Co-production and Usability Study in Pakistan.

Background: Mental health remains among the top 10 leading causes of disease burden globally, and there is a significant treatment gap due to limited resources, stigma, limited accessibility, and low perceived need for treatment. Problem Management Plus, a World Health Organization-endorsed brief psychological intervention for mental health disorders, has been shown to be effective and cost-effective in various countries globally but faces implementation challenges, such as quality control in training, supervision, and delivery. While digital technologies to foster mental health care have the potential to close treatment gaps and address the issues of quality control, their development requires context-specific, interdisciplinary, and participatory approaches to enhance impact and acceptance.

MR imaging of proton beam-induced oxygen depletion.

Background: Previous studies have shown that in-beam magnetic resonance imaging (MRI) can be used to visualize a proton beam during the irradiation of liquid-filled phantoms. The beam energy- and current-dependent local image contrast observed in water was identified to be predominantly caused by beam-induced buoyant convection and associated flow effects. Besides this flow dependency, the MR signal change was found to be characterized by a change in the relaxation time of water, hinting at a radiochemical contribution, which was hypothesized to lie in oxygen depletion-evoked relaxation time lengthening.