Generating Strong Metal-Support Interaction and Oxygen Vacancies in Cu/MgAlO Catalysts by CO Treatment for Enhanced CO Hydrogenation to Methanol.

Strong metal-support interactions (SMSIs) are essential for optimizing the performance of supported metal catalysts by tuning the metal-oxide interface structures. This study explores the hydrogenation of CO to methanol over Cu-supported catalysts, focusing on the synergistic effects of strong metal-support interaction (SMSI) and oxygen vacancies introduced by the CO treatment to the catalysts on the catalytic performance. Cu nanoparticles were immobilized on Mg-Al layered double oxide (LDO) supports and modified with nitrate ions to promote oxygen vacancy generation.

Electrochemical detection of extracellular vesicles for early diagnosis: a focus on disease biomarker analysis.

This review article presents a detailed examination of the integral role that electrochemical detection of extracellular vesicles (EVs) plays, particularly focusing on the potential application for early disease diagnostics through EVs biomarker analysis. Through an exploration of the benefits and challenges presented by electrochemical detection vetted for protein, lipid, and nucleic acid biomarker analysis, we underscore the significance of these techniques. Evidence from recent studies renders this detection modality imperative in identifying diverse biomarkers from EVs, leading to early diagnosis of diseases such as cancer and neurodegenerative disorders.

Structured protein probes modified with selenium nanoparticle for 1-minute measurement of SARS-CoV-2 antigen.

Conventional point-of-care lateral flow immunoassays are characterized by an antibody-tagged probe irregular coupling that can limit sensitivity and require a long assay's time. We synthesized polyethylene glycol-modified selenium nanoparticles (PEG-SeNPs) by template method and developed a strategy to set antibody probes targeted and orderly by using PEG-SeNPs. Synthesized PEG-SeNPs with high stability could immobilize antibodies in the "stand-up" orientation, resulting in a faster detection time of less than 1 min by direct observer visualization without instruments or equipment.

Photocatalytic CO Reduction Coupled with Oxidation of Benzyl Alcohol over CsPbBr@PANI Nanocomposites.

Herein, we successfully prepare conductive polyaniline (PANI)-encapsulated CsPbBr perovskite nanocrystals (PNCs) that demonstrate much improved photocatalytic performance and stability toward the CO reduction reaction (CRR) coupled with oxidation of benzyl alcohol (BA) to benzaldehyde. Due to the acid-base interaction between CO and PANI, CO molecules are selectively adsorbed on PANI in the form of carbamate. As a result, the rate of production of CO () reaches 26.

Utilizing risk-controlling prediction calibration to reduce false alarm rates in epileptic seizure prediction.

Introduction: Epilepsy is a neurological disease characterized by sudden, unprovoked seizures. The unexpected nature of epileptic seizures is a major component of the disease burden. Predicting seizure onset and alarming patients may allow timely intervention, which would improve clinical outcomes and patient quality of life.

High-Index Faceted Cu O@CuO Mesocrystals Act as Efficient Catalyst for Si Hydrochlorination to Trichlorosilane.

Mesocrystals (MCs) with high-index facets may have superior catalytic properties to those with low-index facets and their nanocrystal counterparts. However, synthesizing such mesocrystal materials is still very challenging because of the metastability of MCs and energetic high-index crystal facets. This work reports a successful solvothermal method followed by calcination for synthesizing copper oxide-based MCs possessing a core-shell structure (denoted as Cu O@CuO HIMCs).

Ca pushes and pulls energetics to maintain ATP balance in atrial cells: computational insights.

To maintain atrial function, ATP supply-to-demand matching must be tightly controlled. Ca can modulate both energy consumption and production. In light of evidence suggesting that Ca affects energetics through "push" (activating metabolite flux and enzymes in the Krebs cycle to push the redox flux) and "pull" (acting directly on ATP synthase and driving the redox flux through the electron transport chain and increasing ATP production) pathways, we investigated whether both pathways are necessary to maintain atrial ATP supply-to-demand matching.

Toward a new generation of permeable skin electronics.

Skin-mountable electronics are considered to be the future of the next generation of portable electronics, due to their softness and seamless integration with human skin. However, impermeable materials limit device comfort and reliability for long-term, continuous usage. The recent emergence of permeable skin-mountable electronics has attracted tremendous attention in the soft electronics field.

Isolating Contiguous Ir Atoms and Forming Ir-W Intermetallics with Negatively Charged Ir for Efficient NO Reduction by CO.

The lack of efficient catalysts with a wide working temperature window and vital O and SO resistance for selective catalytic reduction of NO by CO (CO-SCR) largely hinders its implementation. Here, a novel Ir-based catalyst with only 1 wt% Ir loading is reported for efficient CO-SCR. In this catalyst, contiguous Ir atoms are isolated into single atoms, and Ir-W intermetallic nanoparticles are formed, which are supported on ordered mesoporous SiO (KIT-6).

CO Activation and Hydrogenation on Cu-ZnO/AlO Nanorod Catalysts: An In Situ FTIR Study.

CuZnO/AlO is the industrial catalyst used for methanol synthesis from syngas (CO + H) and is also promising for the hydrogenation of CO to methanol. In this work, we synthesized AlO nanorods (n-AlO) and impregnated them with the CuZnO component. The catalysts were evaluated for the hydrogenation of CO to methanol in a fixed-bed reactor.

Lewis base sites of non-oxide supports boost oxygen absorption and activation over supported Pt catalysts.

Formaldehyde (HCHO) oxidation to improve indoor air quality has attracted extensive attention. Designing efficient catalysts for HCHO removal at room temperature still remains challenging. Herein, we report a novel strategy to boost HCHO oxidation by the synergistic effect of Pt nanoparticles and CN.

Skin bioelectronics towards long-term, continuous health monitoring.

Skin bioelectronics are considered as an ideal platform for personalised healthcare because of their unique characteristics, such as thinness, light weight, good biocompatibility, excellent mechanical robustness, and great skin conformability. Recent advances in skin-interfaced bioelectronics have promoted various applications in healthcare and precision medicine. Particularly, skin bioelectronics for long-term, continuous health monitoring offer powerful analysis of a broad spectrum of health statuses, providing a route to early disease diagnosis and treatment.

Large Deflections of Thin-Walled Plates under Transverse Loading-Investigation of the Generated In-Plane Stresses.

Thin-walled plates subjected to transverse loading undergoing large deflection have been the topic of a large number of studies. However, there is still a lack of information about the nature and the distribution membrane stresses generated under large deflections. The purpose of this paper is to calculate and display the distribution of the generated stresses and the respective deflections on the entire rectangular plate area.

Impacts of the Catalyst Structures on CO Activation on Catalyst Surfaces.

Utilizing CO as a sustainable carbon source to form valuable products requires activating it by active sites on catalyst surfaces. These active sites are usually in or below the nanometer scale. Some metals and metal oxides can catalyze the CO transformation reactions.

Modelling of Elongational Flow of HDPE Melts by Hierarchical Multi-Mode Molecular Stress Function Model.

The transient elongational data set obtained by filament-stretching rheometry of four commercial high-density polyethylene (HDPE) melts with different molecular characteristics was reported by Morelly and Alvarez [Rheologica Acta 59, 797-807 (2020)]. We use the Hierarchical Multi-mode Molecular Stress Function (HMMSF) model of Narimissa and Wagner [Rheol. Acta 54, 779-791 (2015), and J.

Visualizing and Quantifying Irregular Heart Rate Irregularities to Identify Atrial Fibrillation Events.

Background: Screening the general public for atrial fibrillation (AF) may enable early detection and timely intervention, which could potentially decrease the incidence of stroke. Existing screening methods require professional monitoring and involve high costs. AF is characterized by an irregular irregularity of the cardiac rhythm, which may be detectable using an index quantifying and visualizing this type of irregularity, motivating wide screening programs and promoting the research of AF patient subgroups and clinical impact of AF burden.

Architectural CuO@CuO mesocrystals as superior catalyst for trichlorosilane synthesis.

As compared with conventional nanocrystal systems, Cu-based mesocrystals have demonstrated distinct advantages in catalytic applications. Here, we report the preparation of a novel architectural CuO@CuO catalyst system integrated with the core/shell and mesocrystal structures (CuO@CuO MC) via a facile solvothermal process followed by calcination. The formation mechanism of the CuO@CuO MC with hexapod morphology was deciphered based on a series of time-dependent experiments and characterizations.

Recycling the CoMo/AlO catalyst for effectively hydro-upgrading shale oil with high sulfur content and viscosity.

Hydrotreatment is an effective upgrading technology for removing contaminants and saturating double bonds. Still, few studies have reported the hydro-upgrading of shale oil, with unusually high sulfur (13200 ppm) content, using the CoMo/AlO catalyst. Here we report an extensive study on the upgrading of shale oil by hydrotreatment in a stirred batch autoclave reactor (500 ml) for sulfur removal and viscosity reduction.

Robust Fabrication of Composite 3D Scaffolds with Tissue-Specific Bioactivity: A Proof-of-Concept Study.

The basic requirement of any engineered scaffold is to mimic the native tissue extracellular matrix (ECM). Despite substantial strides in understanding the ECM, scaffold fabrication processes of sufficient product robustness and bioactivity require further investigation, owing to the complexity of the natural ECM. A promising bioacive platform for cardiac tissue engineering is that of decellularized porcine cardiac ECM (pcECM, used here as a soft tissue representative model).

Structural Design and Synthesis of an SnO @C@Co-NC Composite as a High-Performance Anode Material for Lithium-Ion Batteries.

To overcome the drawbacks of the structural instability and poor conductivity of SnO -based anode materials, a hollow core-shell-structured SnO @C@Co-NC (NC=N-doped carbon) composite was designed and synthesized by employing the heteroatom-doping and multiconfinement strategies. This composite material showed a much-reduced resistance to charge transfer and excellent cycling performance compared to the bare SnO nanoparticles and SnO @C composites. The doped heteroatoms and heterostructure boost the charge transfer, and the porous structure shortens the Li-ion diffusion pathway.

Single-atom Sn-Zn pairs in CuO catalyst promote dimethyldichlorosilane synthesis.

Single-atom catalysts are of great interest because they can maximize the atom-utilization efficiency and generate unique catalytic properties; however, much attention has been paid to single-site active components, rarely to catalyst promoters. Promoters can significantly affect the activity and selectivity of a catalyst, even at their low concentrations in catalysts. In this work, we designed and synthesized CuO catalysts with atomically dispersed co-promoters of Sn and Zn.

Biological and mechanical interplay at the Macro- and Microscales Modulates the Cell-Niche Fate.

Tissue development, regeneration, or de-novo tissue engineering in-vitro, are based on reciprocal cell-niche interactions. Early tissue formation mechanisms, however, remain largely unknown given complex in-vivo multifactoriality, and limited tools to effectively characterize and correlate specific micro-scaled bio-mechanical interplay. We developed a unique model system, based on decellularized porcine cardiac extracellular matrices (pcECMs)-as representative natural soft-tissue biomaterial-to study a spectrum of common cell-niche interactions.

The effect of AZD2171- or sTRAIL/Apo2L-loaded polylactic-co-glycolic acid microspheres on a subcutaneous glioblastoma model.

Studies with AZD2171-a new anti-angiogenic inhibitor of tyrosine kinases associated with VEGF signaling-have shown great promise for treating glioblastoma. Unfortunately, AZD2171 success is limited by low permeability through the blood-brain barrier. Due to AZD2171's short half-life and high toxicity, its local administration will require multiple intracranial procedures, making this approach clinically unfeasible.