3 results match your criteria: "Technical University of Munich Boltzmannstraße 15 85748 Garching Germany.[Affiliation]"
Pilot-scale co-precipitation synthesis of a novel active ingredient made of ultrasmall iron (oxyhydr)oxide nanoparticles for the treatment of hyperphosphatemia.
RSC Adv
May 2024
Chair of Bioseparation Engineering, School of Engineering and Design, Technical University of Munich Boltzmannstraße 15 85748 Garching Germany.
Article Synopsis
- Co-precipitation is a simple and commonly used method for creating iron (oxyhydr)oxide nanoparticles, but its sensitivity to process changes has limited production scale to 1.2 L so far.
- This study successfully scaled up the co-precipitation method to produce 100 L of nanoparticles while maintaining synthesis efficacy and yield across various scales, with only minor variations in component content.
- Characterization techniques showed that while the iron (oxyhydr)oxide cores became smaller, there were no significant structural changes, confirming that high-yield, ultrasmall nanoparticles can be produced on a larger scale.
Chemically fueled supramolecular materials offer unique properties that include spatial and temporal control and even the ability to self-heal. Indeed, a few studies have demonstrated the ability to self-heal, however, the underlying mechanisms remain unclear. Here, we designed a peptide that forms a fibrillar network upon chemical fueling.
View Article and Find Full Text PDFCharacterization of an active ingredient made of nanoscale iron(oxyhydr)oxide for the treatment of hyperphosphatemia.
RSC Adv
May 2021
Bioseparation Engineering Group, Department of Mechanical Engineering, Technical University of Munich Boltzmannstraße 15 85748 Garching Germany
Kidney disease is one of the main non-communicable diseases. Every year millions of people worldwide die from kidney dysfunction. One cause is disturbances in the mineral metabolism, such as abnormally high phosphate concentrations in the blood, medically referred to as hyperphosphatemia.
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