Survival Rate and Short-Term Outcomes of Periviable Preterm Infants: A Single-Center Experience From the United Arab Emirates.

The limit of periviability is constantly changing as infants born at 22-25 weeks of gestation increasingly survive. The data from our region are limited due to the small numbers of these infants among the NICU population. In this study, we evaluated the survival rates and short-term outcomes among preterm neonates between 22 and 24 weeks of gestation admitted to Tawam Hospital, United Arab Emirates.

A Path to Resilience: The Impact of School-Based Yoga on Adolescent Mental Well-Being.

Adolescent mental health is an increasing global concern, with rising levels of stress, anxiety, and depression driven by academic pressure and social expectations. School-based yoga programs are accessible and efficacious interventions for improving mental well-being. Systematic reviews and randomised controlled trials have indicated that yoga interventions improve psychological, cognitive, and physical outcomes in youth, addressing both preventive and therapeutic mental health needs.

Haematologic outcomes and associated clinical characteristics among patients receiving Olaparib therapy in the UAE: a retrospective chart review.

Background: Poly ADP ribose polymerase (PARP) inhibitors, such as Olaparib (Lynparza), are pivotal in treating certain cancers, particularly those linked to BReast CAncer gene (BRCA) mutations. Despite its established efficacy, Olaparib use is associated with various adverse events (AEs), notably haematologic toxicities, such as anaemia. This retrospective chart review study aimed to examine haematologic outcomes and associated factors in patients treated with Olaparib at a tertiary hospital in the UAE.

Reference growth charts for height and weight, for the UAE, the UAEMCGS 2 study.

Background: Growth charts are the most commonly used tool for evaluating the development and nutrition of children. The UAE had its first chart produced 30 years ago.

Aim: The goal of the present study was to derive updated growth charts based on the current UAE child population.

Residential Meditation Retreats: A Promise of Sustainable Well-Being?

Meditation retreats are structured programs that immerse participants in focused meditation, mindfulness, and self-reflection over extended periods. Unlike conventional vacations, which prioritize relaxation, meditation retreats combine intensive practice with intentional rest, cultivating emotional regulation, mindfulness, and personal growth. These retreats have grown in popularity for their ability to support mental, emotional, and physical well-being.

Effect of Mediterranean diet and physical activity on healthcare professional depression, burnout and professional fulfillment during COVID-19.

. The mental health of healthcare professionals, especially during the COVID-19 pandemic, is a critical concern. This study investigates the prevalence of burnout and professional fulfillment, depression and the relationship between physical activity and adherence to the Mediterranean diet with depression, burnout and professional fulfillment among healthcare professionals.

Apalutamide in Metastatic Castration-sensitive Prostate Cancer: Results from the Multicenter Real-world ARON-3 Study.

Background And Objective: Apalutamide (APA) is a treatment for metastatic castration-sensitive prostate cancer (mCSPC). In the ARON-3 study we investigated real-world experiences with APA treatment for mCSPC.

Methods: We retrospectively assessed real-world clinical outcomes for patients with mCSPC treated with APA in the ARON-3 study.

Pancreatic Leiomyosarcoma With Multi-organ Metastases: A Rare Case.

This case report describes the diagnosis, treatment, and progression of a 50-year-old male patient diagnosed with stage IV pancreatic leiomyosarcoma with metastases to the liver, lungs, and brain, representing the only case involving both the pancreas and brain documented in the hospital registry with a histopathological diagnosis of leiomyosarcoma. The patient initially presented with chronic abdominal pain, constipation, and weight loss, and subsequent CT scans revealed a large pancreatic mass with metastases to the liver, lungs, and brain. A biopsy confirmed the diagnosis of leiomyosarcoma, and the patient underwent eight cycles of palliative chemotherapy with cisplatin and docetaxel, along with palliative radiotherapy targeting the brain metastases.

Early Cardiac Ischemia-Reperfusion Injury: Interactions of Autophagy with Galectin-3 and Oxidative Stress.

: Cardiovascular diseases are the leading cause of death worldwide, including the United Arab Emirates. Ischemia-reperfusion (IR) injury results in the death of cardiac myocytes that were viable immediately before myocardial reperfusion. We aim to investigate the role of galectin-3 (Gal-3) in autophagy during ischemia-reperfusion injuries.

Impact of online expert interview-based research training on medical trainees' knowledge and confidence: a mixed-methods design.

Background: Research training is important for medical trainees, because it improves their critical thinking, problem-solving, and the application of scientific principles to clinical practice. The COVID-19 Pandemic, which limited trainees' access to hospitals, had also disrupted traditional research training. The International Emergency Medicine Education Project introduced the online Fundamentals of Research in Medicine course to support trainees.

Yoga for Cancer Survivors (YOCAS): A Systematic Review of the YOCAS Program's Impact on Physical and Psychological Well-Being.

Cancer survivors frequently experience prolonged physical and psychological symptoms including cancer-related fatigue (CRF), sleep disturbances, cognitive impairment, and musculoskeletal pain. Conventional treatments for these symptoms have demonstrated limited efficacy, emphasising the need for complementary therapies. The Yoga for Cancer Survivors (YOCAS) program is a structured mind-body intervention designed to address these challenges.

Yoga in Cancer Care: A Bibliometric Analysis of Systematic Reviews.

Yoga has gained recognition as a complementary intervention for managing the physical and psychological challenges faced by patients with cancer. Systematic reviews of yoga interventions have provided valuable insights into their roles in cancer care. This bibliometric analysis aimed to map the trends, contributors, and thematic focus of systematic reviews on yoga interventions in oncology.

Bystander Response and Out-of-Hospital Cardiac Arrest Outcomes (Bro. Study) in 3 Gulf Countries: Protocol for a Prospective, Observational, International Collaboration Study.

Background: : Globally, there is significant variation in the out-of-hospital cardiac arrest (OHCA) survival rate. Early links in the chain of survival, including bystander cardiopulmonary resuscitation (CPR) and the use of an automated external defibrillator at the scene, are known to be of crucial importance, with strong evidence of increased survival rate with good neurological outcomes. The data from the Middle East are limited and report variable rates of bystander CPR and survival.

The need for implementing a standardized, evidence-based emergency department discharge plan for optimizing adult asthma patient outcomes in the UAE, expert meeting report.

Background: Asthma is a common chronic respiratory inflammatory disease that adversely affects patients' quality of life (QoL) and overall well-being. When asthma is not adequately controlled, there is a higher risk of exacerbations and hospitalizations, thereby increasing the direct and indirect costs associated with the treatment and productivity loss. Overreliance on SABA and underutilization of ICS in the management of asthma can result in suboptimal treatment and poor asthma control.

A Novel Missense Heterozygous Mutation in Gene in a Family with Congenital Septal Defects and Cardiomyopathy: Case Series and Literature Review.

Single-gene mutations are important causes of congenital heart defects in children. Mutations in the gene have been recently described in the literature as a cause of septal defects and cardiomyopathy. However, the spectrum of cardiac disease associated with gene mutations is variable, ranging from asymptomatic septal defects to cardiomyopathy and sudden death.

Thresholds for the value judgement of health technologies in the United Arab Emirates: a consensus approach through voting sessions.

Background: In the evolving healthcare landscape of the United Arab Emirates (UAE), establishing cost-effectiveness thresholds (CETs) is pivotal to informing decision-makers about the value of health technologies.

Objective: This study aimed to establish CETs for the UAE that harmonise with international standards while reflecting the nation's unique healthcare needs and economic context.

Setting: United Arab Emirates.

Fever in Pregnancy: A Rare Case of Listeria-Induced Chorioamnionitis.

Listeriosis is a rare infection during pregnancy and may result in complications such as chorioamnionitis. Diagnosis is hardly made due to the nonspecific symptoms of listeriosis. A 27-year-old pregnant woman at 27 weeks and 3 days of gestation was admitted with a history of fever for 6 days and decreased fetal movement.

Yoga Nidra: A Promising Complementary Therapy for Enhancing Cancer Care.

Cancer patients encounter not only the physical manifestations of their disease but also a range of psychological challenges, including anxiety, depression, and severe sleep disturbances. Research indicates that approximately 50% of cancer patients experience clinically significant levels of distress, which can adversely affect treatment outcomes and diminish their overall quality of life. Moreover, the side effects of treatments such as chemotherapy and radiotherapy frequently exacerbate mental health difficulties, creating an urgent need for effective alternative supportive interventions to ameliorate these symptoms.

Expert Consensus Recommendations on a Biosimilars Value Framework for the Gulf Cooperation Council Countries.

Objective: This paper aims to develop a biosimilar value framework with local stakeholders in Gulf Cooperation Council (GCC) countries.

Methods: A convenience sample of ten key opinion leaders from the United Arab Emirates, Kingdom of Saudi Arabia, Kuwait, Oman and Qatar participated in an expert panel meeting in November 2022 that examined factors positively influencing biosimilar adoption in these countries. The discussion was structured around a conceptual biosimilar value framework and an overview of biosimilar policies as derived from a targeted review of the peer-reviewed and grey literature.

Carbamoly-phosphate synthetase 1 (CPS1) deficiency: A tertiary center retrospective cohort study and literature review.

Background: Protein metabolism and urea production maintain protein and amino acid homeostasis in normal status. Ammonia results from amino acid turnover and is produced by intestinal urease-positive bacteria. Ammonia must be detoxified, and the urea cycle converts ammonia into urea.

Dietary patterns during pregnancy in relation to maternal dietary intake: The Mutaba'ah Study.

Aim: To relate adherence to healthy dietary patterns, evaluated by different dietary indices, to the intake of nutrients and food groups among pregnant women in the United Arab Emirates.

Methods: The analyses included 1122 pregnant women from the Mutaba'ah Study. Dietary intake was assessed using a semi-quantitative Food Frequency Questionnaire.