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Detection by (18)F-FDG PET of unsuspected extensive bone marrow metastases in a case of basosquamous carcinoma of the cheek.
Hell J Nucl Med
April 2016
Radiation Medicine Centre, Bhabha Atomic Research Centre, Department of Pathology, Tata Memorial Hospital Jerbai Wadia Road, Parel, 400 012 Mumbai.
Article Synopsis
- Basosquamous carcinoma (BSC) is a rare, aggressive malignancy that combines features of both basal and squamous cell carcinoma, with higher risks of recurrence and metastasis than typical basal cell carcinoma.
- An unusual case involved a 32-year-old man whose BSC, initially identified on the left cheek, was found to have extensive metastasis in the bone marrow through a (18)F-FDG PET scan, leading to further confirmation by biopsy.
- This case is notable as it is the first documented instance of using (18)F-FDG PET to diagnose advanced metastatic BSC in the bone marrow, highlighting the aggressive nature of this cancer at initial diagnosis.