Kaleidoscopic Chloroma: An Unusual Case of Myeloid Sarcoma.

We report a 37-year-old male patient who had nonbilious vomiting, no passage of flatus, and recurring abdominal pain. This patient had de novo intestinal myeloid sarcoma (MS), a rare and chameleonic presentation of acute leukemia of myeloid origin. The initial diagnostic evaluation suggested Koch's abdomen, and surgical excision of the bowel was performed with a clinical suspicion of Koch's or lymphoma.

A Core Outcome Set for Adult General ICU Patients.

Objectives: Randomized clinical trials informing clinical practice (e.g., like large, pragmatic, and late-phase trials) should ideally mostly use harmonized outcomes that are important to patients, family members, clinicians, and researchers.

Newer Biomarkers in Gallbladder Carcinoma: A Scoping Review.

Biomarkers have the potential to play a crucial role in managing gallbladder cancer post-surgery. They can identify patients more likely to experience a recurrence, allowing oncologists to tailor a more intensive surveillance plan and consider additional therapies. Some biomarkers can even predict how well a patient will respond to specific chemotherapy or targeted treatments.

Ewing's sarcoma of the head and neck: differential diagnosis, treatment and outcomes.

Purpose Of Review: Ewing's sarcoma is a small round-cell tumour typically arising in the bones, and only rarely affecting soft tissues. These are rarely seen in the head and neck comprising 1-9% of all cases, making management of these tumours a challenge. This review aims to review the current literature to update the current diagnostic and treatment options in head and neck Ewing's sarcoma.

The Appropriate Utilization of Beta-Blockers in Acute Coronary Syndrome Patients: An Improvement Initiative.

Background and objective Beta-blockers are a cornerstone in the management of acute coronary syndrome (ACS), effectively reducing myocardial oxygen demand, preventing recurrent ischemia, and lowering the risk of arrhythmias and reinfarction. Despite several established guidelines, such as those by the American College of Cardiology/American Heart Association (ACC/AHA), advocating their use within 24 hours for eligible patients, beta-blockers remain underutilized in clinical practice. This study aimed to analyze beta-blocker utilization patterns in ACS management and evaluate the impact of targeted improvement initiatives on their appropriate use in eligible ACS patients.

Acute Psychosis as Presenting Symptoms of Vitamin B12 Deficiency: A Case Series.

Background: Vitamin B12 deficiency is a prevalent condition affecting a significant proportion of India's population, with implications for mental health. Despite its established link to psychiatric symptoms, vitamin B12 deficiency often remains underdiagnosed. The aim of this study is to highlight the association between vitamin B12 deficiency and acute psychosis, emphasizing the importance of early detection and treatment.

Balancing bleeding, thrombosis and myocardial injury: A call for balance and precision medicine for aspirin in neurosurgery.

Perioperative management of antiplatelet therapy involves a delicate balancing of the risk of periprocedural blood loss with the cardiovascular and thrombotic risk to the patient. Due to the unique nature of neurosurgery, perioperative bleeding may have devastating consequences and cause major morbidity and mortality. The recommendation to discontinue aspirin prior to major neurosurgical procedures rests upon conventional practice, expert consensus with priority given to avoidance of any major bleed.

Update on the aetiopathogenesis of obstructive sleep apnea: Role of inflammatory and immune mediated mechanisms.

Obstructive sleep apnea (OSA) is often a lifestyle disease associated with obesity, which is rapidly evolving as a major health concern with diverse multisystemic implications. To prevent and mitigate its adverse effects and reduce its burden on society, its aetiopathogeneses must be precisely understood. Numerous studies focusing on the range of diverse anatomic, functional, and lifestyle factors have already been carried out to determine the possible contributory roles of these factors in OSA.

Enigma of Gastric Teratoma in Infants: A Case Series.

Gastric teratomas are an extremely rare variety of teratomas in children. The aim of our series is to present the natural history and progression of the disease. Retrospective analysis of prospectively maintained data of all the gastric teratoma patients treated at our center was done from their electronic medical records.

Portal Venous Tumor Thrombosis and Visceral Organ Metastasis without Skeletal Involvement in mCRPC: Adverse Prognostic Indicators on Dual Tracer PET/CT and Clinical Outcome after Lu-PSMA-617 PRLT and Cabazitaxel Therapy.

Prostate cancer involving visceral organs are occurrences in the later disease course, usually following regional nodal and skeletal involvement, and are refractory to conventional treatment. A 61-year-old male patient presented with locally advanced disease at presentation, which progressed on androgen deprivation therapy and systemic therapy with involvement of the visceral organs (lungs and liver). Portal venous tumor thrombosis involving the right and main branch was also observed on contrast-enhanced computed tomography (CECT) and magnetic resonance imaging (MRI), which showed intense uptake on Ga-labeled prostate-specific membrane antigen positron emission tomography/computed tomography ( Ga-PSMA-11 PET/CT) and F-fluorodeoxyglucose PET/CT ( F-FDG-PET/CT).

Unraveling the Complexity of Vaginismus in Marital Relationship: A Case Series.

This article presents a case series examining the interplay between marital dynamics and the management of vaginismus. Vaginismus is a spasm of the perivaginal muscles sufficient to prevent penile entry or make it uncomfortable. Given the multifactorial nature of vaginismus, with psychological and relational factors playing significant roles, understanding these dynamics is crucial for effective treatment.

Metacarpophalangeal Joint Dislocations Two Cases, Two Stories.

Introduction: Metacarpophalangeal (MCP) joint dislocation and its pathoanatomy was first discussed in detail in an article written by Kaplan et al . ,in 1957. They had identified certain features of complex, that is irreducible MCP joint dislocation through closed method to differentiate from a simple MCP joint dislocation, that is MCP joint dislocation that can be reduced by closed method.

A Cheaper Alternative to Conventional Mid-urethral Sling Surgery Can Also Have Comparable Obstetric Outcome in the Long Term: A Case Report.

Stress urinary incontinence (SUI) is a common disorder in females, which significantly affects the quality of life in females. There are many consensus that describe the safety of childbearing after surgery for SUI, but still, a large proportion of surgeons worldwide recommend that women should wait to complete childbearing before pursuing surgical treatment for SUI. There is also some opinion that if patients conceive after surgical treatment for SUI, women should be delivered by cesarean section.

Giant Broad Ligament Leiomyoma: A Diagnostic and Surgical Challenge.

Broad ligament leiomyomas are rare tumors present outside the uterine body. The incidence of giant broad ligament leiomyomas (weighing over 3 kg) remains relatively rare. In this report, we present the case of a peri-menopausal woman who came in with a large abdominal mass.

Uncovering the Hidden Threat: Ileocolic Intussusception in an Adult With Appendicular Tumor.

Intussusception in adults is a rare condition, often associated with an underlying pathological lead point. This case report describes a case of intussusception in a 37-year-old female patient with an unusual lead point: an appendicular mucinous neoplasm. This case highlights the clinical presentation, diagnostic process, and management of adult intussusception caused by an appendicular neoplasm.

Severe and Persistent Thrombocytopenia in an Adolescent Girl Following Dengue Infection Manifesting As Pulmonary Hemorrhage.

Thrombocytopenia is common in the critical phase of dengue due to decreased production from the bone marrow and increased peripheral destruction of platelets. Platelet count improves with resolution of the disease. However, further evaluation is required if thrombocytopenia persists for a longer period following dengue infection.

Treating a Refractory Locally Advanced Carcinoma of the Cervix With Cone-Beam Computed Tomography-Based Adaptive External Beam Radiotherapy: A Case Report.

Adaptive radiotherapy (ART) refers to methods that allow a radiation therapy plan to be adjusted based on images obtained during the treatment. Using cutting-edge imaging methods such as computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), ART can adjust the treatment plan in response to observed changes in anatomy and even biology while the patient is receiving treatment. The backbone of ART is intensity-modulated RT (IMRT), which permits better sparing of normal critical organs while still delivering a uniform dose to target tumor volume.

Can combined paravertebral and erector spinae block provide perioperative analgesia for mastectomy with LD flap reconstruction surgery? An observational study.

Background: Mastectomy and breast reconstruction with latissimus dorsi myocutaneous flap (LDF) is a major surgery that covers eight or more dermatomes causing severe pain in the postoperative period.

Objectives: We evaluated the analgesic effect of a hybrid technique of ultrasound-guided combined thoracic paravertebral block (TPVB) and erector spinae plane block (ESPB) in a single needle pass in ten consecutive patients scheduled for mastectomy with LDF reconstruction as a part of a multimodal analgesia regimen.

Design: Prospective observational study.

, a new genus of jumping spiders (Salticidae, Plexippina) from South Asia, with the new Indian species .

We describe a new plexippine genus, , supported by phylogenomic data from ultraconserved elements (UCEs), Sanger sequences of four genes, and morphological evidence. The type species, (Caleb, Christudhas, Laltanpuii & Chitra, 2014), is transferred from , as is (Caleb, 2022), The phylogenomic data places among the plexippines near C.L.

Henri Coutard (1876-1950): A Pioneer of Fractionated Radiotherapy Regimens.

Henri Coutard was a prominent French roentgen therapist (radiation therapist). He was a pioneer physician and scientist who established the development of the "protracted-fractional method" of radiation dosing. He treated laryngeal cancer with super-voltage x-rays and also published data on five-year survival rates while his contemporary physicians indulged in treating cancer with radioactive sources.