Effectiveness of non-invasive vagal nerve stimulation in Parkinson's disease: A comprehensive systematic review and meta-analysis.

Background: Parkinson's disease (PD) is a debilitating neurodegenerative disorder characterized by movement impairments. Vagus nerve stimulation (VNS) is a non-invasive brain stimulation technique that has shown promise in treating various neurological conditions, including PD. This systematic review aimed to evaluate the existing evidence on the efficacy of nVNS in managing PD symptoms.

Subthalamic nucleus versus globus pallidus internus deep brain stimulation in the treatment of dystonia: A systematic review and meta-analysis of safety and efficacy.

Objective: This systematic review and meta-analysis aimed to compare the efficacy and safety of deep brain stimulation (DBS) targeting subthalamic nucleus (STN) versus the globus pallidus internus (GPI) in the treatment of dystonia.

Methods: A comprehensive search strategy was implemented up to July 2024, across five databases, identifying studies relevant to STN-DBS and GPI-DBS in dystonia. Eligibility criteria included randomized controlled trials (RCTs) and observational studies comparing the two interventions.

Spigelian Hernia Unveiled: A Case Report of Unexpectedly Extended Hernial Sac and Successful Surgical Intervention.

Spigelian hernia is a rare type of abdominal hernia; diagnosis is primarily through computed tomography, which is crucial for accurate diagnosis and planning early surgical intervention to preserve the herniated sac's contents.

The dermatological manifestations and differential diagnosis of monkeypox: A narrative review.

Monkeypox (MPX) is a zoonotic viral disease caused by the monkeypox virus (MPXV), which belongs to the Orthopoxvirus genus. The main clinical features of MPX are fever, rash, and lymphadenopathy. It is usually a self-limited disease and can resolve within a few weeks in most cases.

An integrated approach of support vector machine (SVM) and weight of evidence (WOE) techniques to map groundwater potential and assess water quality.

This study addresses the critical need for effective groundwater (GW) management in Muzaffarabad, Pakistan, amidst challenges posed by rapid urbanization and population growth. By integrating Support Vector Machine (SVM) and Weight of Evidence (WOE) techniques, this study aimed to delineate GW potential zones and assess water quality. This study fills the gap in applying advanced machine learning and geostatistical methods for accurate GW potential mapping.

Complex complications following ventriculoperitoneal shunt placement in Syria: A case report on multiple bowel perforations, migration, and obstruction.

Introduction: In patients with hydrocephalus, the most effective technique since the early 1900s is through the implantation of a ventriculoperitoneal shunt (VPS). VPS can cause abdominal issues such as infection, bowel obstruction due to adhesions, or viscus perforation. In our patient, the combination of infection, bowel obstruction, multiple intestinal perforations, and anal migration of the shunt creates a unique blend of complications that may be caused by VPS.

Unveiling urban air quality dynamics during COVID-19: a Sentinel-5P TROPOMI hotspot analysis.

In India, the spatial coverage of air pollution data is not homogeneous due to the regionally restricted number of monitoring stations. In a such situation, utilising satellite data might greatly influence choices aimed at enhancing the environment. It is essential to estimate significant air contaminants, comprehend their health impacts, and anticipate air quality to safeguard public health from dangerous pollutants.

GERD: Latest update on acid-suppressant drugs.

GERD is a very familiar diagnosis among health care providers due to its massive spread, and its symptoms can affect the quality of life for a respectable slice of its patients. Therefore, what can only be described as a logical consequence, a pursuit of a treatment that can both relieve symptoms and have minimal side effects is still ongoing to cover the large demographic affected by GERD. In the following review, analysis will be made of GERD, including possible regulatory activity, of certain drugs to the already discussed pathways involved in GERD patients.

Spontaneous resolution of synovial lumbar cyst presented with severe symptoms: a case report.

Introduction: Spinal cysts have traditionally been treated with surgery since it was first described in 1950. However, there have been rare instances where these cysts have resolved on their own without the need for surgical intervention. Here, we discuss the 27th reported case of such spontaneous resolution in the medical literature and delve into the details of this unique case.

The relationship between gender and pharmacology.

The part of sexuality in pharmacology research was not acknowledged, and it was not thought-out to be a determinant that could impact strength and disease. For decades research has mainly contained male, women and animals, leading to a lack of news about syndromes in females. Still, it is critical to guarantee equal likeness so that determine the security, influence, and resistance of healing agents for all individuals.

A rare case of benign retrorectal teratoma in an adult female: Diagnostic challenges and successful surgical management.

Introduction: Retrorectal tumors are rare growths with various types which are found in the space behind the rectum. They can be diverse and are often diagnosed through imaging and surgery.

Presentation: A 31-year-old female patient came to the clinic with concerns about irregular periods and constipation, but no history of abdominal pain, pelvic pressure, or weight loss.

A successful management of Candy Cane syndrome post Roux-en-Y gastric bypass: a rare case report.

Introduction And Importance: Candy Cane syndrome (CCS) is a rare condition in which the proximal gastrojejunal attachment's afferent blind limb is elongated. This can lead to different symptoms, including nausea and vomiting, with less commonly described reflux and regurgitation symptoms.

Case Presentation: A 38-year-old female presented with a chronic complaint of postprandial pain, discomfort, and reflux lasting for about 2 years after a previous Roux-en-y gastric bypass (RYGB) surgery.

Massive cystic falcine meningioma presented with slight symptoms: a case report.

Introduction And Importance: Meningiomas are the most common intracranial tumors while their presence with cysts is relatively low. In general, large ones usually present with severe symptoms and have a high recurrence rate even after total resection which is also difficult.

Case Presentation: The authors present a case of an elderly patient with a large Falcine meningioma associated with peritumoral cysts.

Early diagnosis and treatment of perianal Crohn's disease in a 1-year-old infant: Case report and review of literature.

Inflammatory bowel disease is rare in infants and it includes perianal Crohn's disease, which is inflammation at or near the anus. An early diagnosis is essential to prevent the complications that may affect the development and growth of the child.

Subclavian steal syndrome: a case study of diagnosis, management, and successful surgical resolution.

Subclavian steal syndrome (SSS) is a rare vascular condition characterized by retrograde blood flow in the vertebral artery, often discovered incidentally in asymptomatic patients. We present a 65-year-old male with recurrent transient ischemic attacks (TIAs) attributed to 99% stenosis at the origin of the left subclavian artery, leading to SSS. Diagnostic modalities included duplex ultrasound, confirming inverted left vertebral artery flow, and multi-slice computed tomography angiography, confirming the diagnosis.

A male fetus with cyclopia was discovered after miscarriage: A rare case report from Syria.

Key Clinical Message: This case of alobar holoprosencephaly and cyclopia emphasizes the value of prenatal check-ups, particularly in low-income countries. Early ultrasound diagnosis leads to early gestational termination, preventing psychological trauma for the parents.

Abstract: Alobar holoprosencephaly is a rare-occurrence malformation with a bad prognosis linked to cyclopia, the most severe cranial feature.

A new cloud-based method for composition of healthcare services using deep reinforcement learning and Kalman filtering.

Healthcare has significantly contributed to the well-being of individuals around the globe; nevertheless, further benefits could be derived from a more streamlined healthcare system without incurring additional costs. Recently, the main attributes of cloud computing, such as on-demand service, high scalability, and virtualization, have brought many benefits across many areas, especially in medical services. It is considered an important element in healthcare services, enhancing the performance and efficacy of the services.

Bartter syndrome in a female infant: A rare case report from Syria.

Antenatal Bartter syndrome is a rare condition that affects approximately 1.2 individuals per million. It is caused by renal tubular dysfunction that impairs the reabsorption of sodium and chloride.

Overlapping between squamous cell carcinoma and mucocutaneous leishmaniasis in a diabetic patient.

Mucocutaneous leishmaniasis (MCL) is a leishmania infection; that usually affects the oral and nasal mucosa. The coexistence of leishmania and malignancy is rarely reported and mainly in immunocompromised patients. We report a case of an overlapping between leishmania and squamous cell carcinoma (SCC) in a 60-year-old immunocompetent Syrian female.

Double aneuploidy in a 2-month-old male with Edward syndrome and Klinefelter syndrome: a case report.

Introduction And Importance: Edward syndrome is a severe chromosomal defect that occurs as a result of non-disjunction through meiosis. It presents with cardiac septal defects, horseshoe kidneys, patent ductus arteriosus, central nervous system dysgenesis, distinctive craniofacial deformities, and overriding or overlapping fingers. Klinefelter syndrome (47, XXY) is found in 1 in 660 newborn males.

Prevalence of Keratoconus and Keratoconus Suspect among Patients Seeking Refractive Surgery in Syria.

Purpose: The purpose of this study was to determine the prevalence of keratoconus (KC) and keratoconus suspect (KCS) among patients seeking refractive surgery in Syria.

Methods: This is a retrospective multicenter screening study. The study was conducted in Damascus University, Tishreen University, and Tartous Specialist Eye Center (a private center).