Optimized microwave-assisted extraction and characterization of spray dried Luffa aegyptiaca nanomucilage: Physicochemical properties, biological activities, and anticancer efficacy against MCF-7 human breast cancer cells.

Microwave-assisted extraction conditions were optimized using response surface methodology to evaluate the effects of extraction parameters on the yield and carbohydrate content of Luffa aegyptiaca mucilage. Extraction at 540 W for 2 min with a 1:20 (g/mL) was determined as the optimal parameter, resulting in a maximum yield of 5.90 % (w/w) with 63 % carbohydrate content consisting of glucose, galactose, maltose, mannose, and galacturonic acid, with structural linkages of β (1 → 4) and β (1 → 6) glycosidic bonds.

Synthesis, Characterization, and Investigation of Corona Formation of Dipeptide-Based Nanomaterials.

Peptide-based nanomaterials can be easily functionalized due to their functional groups, as well as being biocompatible, stable under physiological conditions, and nontoxic. Here, diphenylalanineamide-based nanomaterials (FFANMs) were synthesized, decorated with Ca ions to set the surface charge, and characterized for possible use in gene delivery and drug release studies. FFANMs were characterized by SEM, TEM, dynamic light scattering (DLS), and LC-MS/MS.

Impact of hopelessness on migration intentions of nursing students: a path analysis.

Background: Brain drain refers to the migration of qualified professionals to developed countries in search of better living and working conditions, and has become a global concern, particularly in the healthcare sector. Migration of highly skilled nurses results in increased workload for the remaining nursing staff, limited access to quality healthcare services, and contributes to disparities in healthcare. Therefore, nursing students represent a critical demographic group for understanding the drivers of brain drain in the healthcare sector.

Exploration of Agrocybe aegerita mushroom polysaccharide-polyphenolic complex: Functional properties, binding efficiency, and biological activities.

This study investigates the functional and biological activities of a polysaccharide-polyphenolic complex derived from the edible mushroom Agrocybe aegerita. Polyphenols were extracted using a modified solvent evaporation technique, and polysaccharides (AMP) were extracted using enzyme-assisted methods, yielding 8.02 %.

Optimization of chromium (VI) reduction in aqueous solution using magnetic Fe3O4 sludge resulting from electrocoagulation process.

The reuse of electro-coagulated sludge as an adsorbent for Cr(VI) ion reduction was investigated in this study. Electro-coagulated sludge was obtained during the removal of citric acid wastewater by the electrocoagulation process. The following parameters were optimized for Cr(VI) reduction: pH (5-7), initial Cr(VI) concentration (10-50 mg/L), contact time (10-45 min), and adsorbent dosage (0.

Screening and identification of potential target of 1'-acetoxychavicol acetate (ACA) in acquired lapatinib-resistant breast cancer.

1'-Acetoxychavicol acetate (ACA) eliminates breast cancer cells via the HER2/MAPK/ERK1/2 and PI3K/AKT pathways, and it also directly influences endocrine resistance by both enhancing pro-apoptotic signals and suppressing pro-survival molecules. This study utilized bioinformatics to assess ACA target genes for lapatinib-resistant breast cancer. We identified differentially expressed genes (DEGs) using GSE16179 microarray data.

Exploring the Link Between Mothers' Spiritual Well-Being and Positive Parenting in the Turkish Context: The Role of Mindful Parenting.

This cross-sectional study examined the role of mindful parenting in the association between spiritual well-being and positive parenting behaviors among mothers of typically developing children. The sample comprised 381 mothers of children aged 4-17 years. We collected the data using the Three-Factor Spiritual Well-Being Scale (SWBS-3), the Mindfulness in Parenting Questionnaire (MIPQ), and the Multidimensional Assessment of Parenting Scale (MAPS).

Novel Schiff Base Sulfonate Derivatives as Carbonic Anhydrase and Acetylcholinesterase Inhibitors: Synthesis, Biological Activity, and Molecular Docking Insights.

Sulfonate derivatives are an essential class of compounds with diverse pharmacological applications. This study presents the synthesis and detailed characterization of six novel Schiff base sulfonate derivatives (L-L) through spectroscopic techniques (FT-IR and NMR). Their inhibitory potential was evaluated against human carbonic anhydrase isoenzymes (hCA I and hCA II) and acetylcholinesterase (AChE), which are crucial therapeutic targets for diseases such as glaucoma, epilepsy, and Alzheimer's disease.

Effect of using a kaleidoscope projector and matching cards on fear and vital signs in children aged 3-6 years receiving inhaled medication.

Aim: The aim of this study was to investigate the effect of the use of projector kaleidoscope and matching card on children's fear and physiological parameters in children aged 3-6 years receiving inhaled medication.

Methods: This randomised controlled study was conducted with the guidelines of Consolidated Standards of Reporting Trials (CONSORT). The sample of children was allocated to the projector kaleidoscope group (n = 38), matching card group (n = 38) and control group (n = 38).

Weakly Solvating Cyclic Ether-Based Deep Eutectic Electrolytes for Stable High-Temperature Lithium Metal Batteries.

Deep eutectic electrolytes (DEE) have emerged as an innovative approach to address the instability and safety issues of lithium metal batteries at elevated temperatures. However, in practice, there is often an undesirable incompatibility between the eutectic mixture and electrodes, and also an insufficient reduction stability of DEE due to the increased Li concentration. Herein, we designed a new DEE by utilizing weakly solvating tetrahydropyran (THP) solvent.

A comparison of watching cartoons versus playing games as a distraction method on pain and fear of pain during peripheral intravenous cannula placement in children aged 6-9 years: A randomized experimental study.

Purpose: This study aimed to compare the effects of watching cartoons and playing games as a distraction method during peripheral intravenous cannula insertion on pain and fear of pain in children aged 6-9 years.

Design & Methods: This RCT with a parallel-group randomized experimental design was conducted between May and July 2024 in the pediatric unit of a university hospital with a tertiary referral centre. Sixty-eight children aged 6-9 years were assigned to two different groups using block randomization method (Cartoon Group = CG; n = 34, Gaming Group = GG; n = 34).

Performance analysis and science mapping of family resilience research in the context of children and adolescents: A bibliometric study.

Problem: The present study explores research on family resilience in the context of children and adolescents, as well as studies covering all family members, and examines the conceptual, intellectual, and social structures of the research through bibliometric analysis.

Materials And Methods: We carried out the search procedure on the abstracts of papers indexed to Social Science Citation Index (SSCI), Science Citation Index Expanded (SCI-E), Emerging Sources Citation Index (ESCI), and Arts & Humanities Citation Index (AHCI) within the Web of Science (WoS) database.

Results: We could access 407 papers since 1994 pertaining to the topic of family resilience in the context of children and adolescents.

Nutraceutical tablets: Manufacturing processes, quality assurance, and effects on human health.

Consumers are increasingly focused on food products' nutritional content and health aspects. Nutraceutical tablets containing nutritional supplements have seen remarkable progress and are well-known for their precise dosage, which can improve consumer health by increasing the intake of bioactive compounds and vital nutrients. Oral nutraceuticals are frequently used to enhance consumer well-being, with around 80% of products being in solid form.

Sustainable algal proteins, novel extraction techniques and applications in the bakery, dairy and pharmaceutical industries: A comprehensive review.

Microalgae have emerged as favorable substitutes for traditional animal-based proteins in the search for sustainable protein sources. Despite being underexplored, microalgae offer the possibility of large-scale protein production via novel extraction techniques. This review synthesizes current knowledge on microalgal proteins, shedding light on their novel extraction techniques and techno-functional properties, which are still in the early stages of exploration.

A comparative study on utilization of different plant-derived nano-mucilage as a fat replacer in yogurt: Product optimization, physicochemical attributes, shelf-life evaluation, and consumer perception with market orientation.

This study aimed to utilize different plant-derived mucilage as a fat substitute in yogurt production. rhizome mucilage (CEM), fruit mucilage (CDM), and husk mucilage (PHM) were extracted using different extraction process, and spray dried to acquire nano-scaled mucilage particles (100-300 nm). Seven different types of yogurts were prepared with the addition of varied mucilage concentrations (1-10 % /).

Synthesis of hydrothermal-assisted papaya peel-derived carbon quantum dots impregnated carboxymethyl cellulose and pectin crosslinked nanohydrogel for shelf-life enhancement of strawberry.

This study focuses on utilizing papaya peel to produce carbon quantum dots (PP-CQDs) via a hydrothermal method and the PP-CQDs are subsequently embedded into carboxymethyl cellulose and pectin nanohydrogel to enhance the shelf-life of strawberries. The synthesis of PP-CQDs was found to be optimal under conditions of 12 h and 200 °C, resulting in a quantum yield of 39.15 % and an average particle size of 4.

Formulation of functional noodles by adding mushroom powder: Physiochemical attributes, cellular mineral uptake and improved glycemic index.

This study investigated the physicochemical, low glycemic index, and mineral uptake of functional noodles added with varying concentrations (0-10 %) of (also known as shiitake) powder. Noodles with 4 % mushroom powder (L3) exhibited comparable sensory attributes in comparison with control noodles. The L3 showed significantly higher protein (1.

Optimization of ultrasonication assisted extraction of fruit shell nano polysaccharide and evaluation of photocatalytic dye reduction and edible coating for fresh-cut fruits.

(AM) fruit shell, considered waste, is an excellent source of bioactive compounds, including polysaccharides. Therefore, this study focuses on the extraction of AM polysaccharides using an ultrasonication-assisted approach. Different parameters, including ultrasonic power (200-600 W), time (5-15 min), and solid-to-solvent ratio (10-20 mg/mL), were employed, and significantly ( < 0.

Arabinogalactans-rich microwave-assisted nanomucilage originated from garden cress seeds as an egg replacement in the production of cupcakes: Market orientation and in vitro digestibility.

The increasing demand for functional foods arises from concerns regarding food allergies, dietary restrictions, and ethical considerations related to egg consumption. Consequently, this study investigates the feasibility of using arabinogalactan-rich nanomucilage derived from garden cress seeds as an egg replacement in cupcake production. The microwave-assisted process resulted in 23.

Effects of the Helfer skin tap technique and Buzzy® application on the levels of pain and fear experienced by children during vaccination: A randomized controlled trial.

Purpose: Vaccination is an invasive procedure that causes pain. Uncontrolled pain negatively affects all aspects of life, including health. This study aimed to determine the effects of the Helfer skin tap technique and Buzzy® application on the levels of pain and fear experienced by 4-year-old children during measles-mumps-rubella (MMR) vaccination.

Toxicity, Antibacterial, Antioxidant, Antidiabetic, and DNA Cleavage Effects of Dextran-Graft-Polyacrylamide/Zinc Oxide Nanosystems.

Synthesis of metal oxide nanoparticles-polymer nanocomposites is an emerging strategy in nanotechnology to improve targeted delivery and reduce the toxicity of nanoparticles. In this study, we report biological effects of previously described hybrid nanocomposites containing dextran-graft-polyacrylamide/zinc oxide nanoparticles (D-PAA/ZnO NPs) prepared from zinc sulfate (D-PAA/ZnONPs(SO)) and zinc acetate (D-PAA/ZnONPs(-OAc)) focusing primarily on their antimicrobial activity. D-PAA/ZnONPs(SO) and D-PAA/ZnONPs(-OAc) nanosystems were tested in a complex way to assess their antioxidant activity (DPPH assay), antidiabetic potential (α-amylase inhibition), DNA cleavage activity, antimicrobial, and antibiofilm activity.

Efficacy of different warming methods for perioperative hypothermia prevention on body temperature and shivering among transurethral resection patients: A systematic review and meta-analysis study.

Purpose: The present study attempts to assess the impacts of distinct warming strategies employed to avert perioperative hypothermia on core body temperature and shivering among transurethral resection patients.

Methods: We performed a comprehensive search of Turkish and English keywords across a range of databases, including PUBMED, Web of Science, Cochrane Library, SCOPUS, Ovid, EBSCOhost, Yöktez, DergiPark, and TR Index, to identify studies on the subject published between January 1, 2001-2024. The search procedure yielded 11 studies to be recruited for meta-analysis.

Global trends in technology-dependent children, home care, and parental discharge education: A bibliometric analysis using Biblioshiny.

Background: Parents of technology-dependent children constitute a different population in society and face diverse problems during caregiving.

Methods: This study aimed to identify and visualize studies conducted from 1990 to 2024 on technology-dependent children, home care, and parental discharge education and determine global trends. A descriptive and bibliometric study design was employed.