117 results match your criteria: "Tarbiat Modares University Tehran Iran.[Affiliation]"

Background And Objectives: Epstein-Barr virus (EBV) infection is ubiquitous all around the world. Tonsils seem to be candidate replication sites for EBV, and these tissues can be infected acutely or chronically. Some studies reported an association between EBV infection and tonsillar hypertrophy.

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Background And Aim: Complementary therapies, such as aromatherapy, were used to manage acute and chronic symptoms of diseases. Anxiety symptoms and deviations in vital signs are frequently manifest in patients admitted to the cardiac care unit (CCU). This study aimed to evaluate the impact of and chamomile aromas on anxiety levels and vital signs of patients hospitalized in CCU.

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Bioactive peptides and protein hydrolysates have gained considerable attention in the food industry and functional food markets due to their diverse health effects, including antioxidant, antihypertensive, and antidiabetic properties. This study aimed to produce combined soy and corn protein hydrolysates using Alcalase (Al), modification of Al-hydrolysates through sequential hydrolysis using Flavourzyme (Al-FL), cross-linking of Al-hydrolysates using microbial transglutaminase (MTGase) (Al-TG), and fractionation of Al-hydrolysates by ultrafiltration (UF) with molecular weight (MW) cut-off of 100 (Al-F4), 30 (Al-F3), 10 (Al-F2), and 2 kDa (Al-F1). Notably, the < 2 kDa fraction (Al-F1) showcased exceptional biological activities, including antioxidant (81.

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The quantity and quality of the active components of plants are strongly influenced by environmental factors. In this regard, dried cumin seeds were collected from four different locations (SaadatShahr (P1) and Sarvestan (P2) from Fars Province and Kashmar (P3) and Sabzevar (P4) from Khorasan), and their essential oils were isolated by Clevenger apparatus and evaluated using GC and GC-MS. In addition, the hypnotic and antinociceptive activities of the cumin EO sample, which had the highest yield and quality, respectively, were assessed via the pentobarbital-induced loss of righting test and acetic acid-induced writhing test.

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The purpose of the present study was to determine the total phenolic, flavonoid, and galegine content and antioxidant activity, as well as the in vitro antidiabetic potential of different extracts of using the solvent extraction method. The results demonstrated that the highest yield of extraction (28.05%) and galegine content (17.

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  • The article with DOI: 10.1039/D3NA00923H has been formally retracted.
  • This means that the findings or claims made in the article are no longer considered valid.
  • Retraction can occur due to issues like errors, misconduct, or ethical breaches in the research process.
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A novel cell-penetrating peptide (CPP) called -YR, with as a fluorescent probe, was developed. Initially, we aimed to use Y as a supramolecular host for water-insoluble drugs, with R driving the complex into cells. However, an unexpected hurdle was discovered; the peptide self-assembled into amorphous aggregates, rendering it ineffective for our intended purpose.

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  • The study investigates the effectiveness of pregnancy-associated plasma protein-A (PAPP-A) in predicting gestational diabetes mellitus (GDM) during the first trimester of pregnancy, as current testing methods may be delayed.
  • By analyzing serum PAPP-A levels in 344 pregnant women using a Bayesian statistical model, researchers sought to evaluate PAPP-A's diagnostic accuracy without relying on the gold standard glucose tolerance test.
  • Results indicated that PAPP-A showed high sensitivity (92%) and specificity (81%) for detecting GDM, suggesting it could be a valuable early screening tool for this condition.
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  • - The study explores the connection between microRNA miR-141, Sirtuin 1 (SIRT1), and non-alcoholic fatty liver disease (NAFLD) in adults, finding significant changes in these factors related to obesity and metabolic health.
  • - In a group of 100 adults, it was revealed that miR-141 levels were higher and SIRT1 expression was lower in those with obesity compared to normal-weight individuals, indicating a negative relationship between the two.
  • - The findings suggest that increased miR-141 could inhibit SIRT1, leading to obesity-related issues like NAFLD, highlighting the potential of miR-141 as a target for diagnosis and treatment in these conditions.
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This study explores the efficacy of a ceramic membrane combining filtration, electrofiltration, and backwashing for oily water treatment. A secondary mullite membrane was synthesized, showcasing high permeate flux (534 LMH), biaxial flexural strength (75.21 MPa), and cost-effectiveness.

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Graphitic carbon nitride (g-CN) nanostructures were synthesized the calcination of urea at various temperatures ranging between 400 and 600 °C and were utilized for photoreduction of Cr(vi) in aqueous medium. Due to the low adsorption of Cr(vi) on the g-CN surface, a more accurate assessment of the photocatalytic performance of the samples was carried out. Although the characterization showed that the specific surface of samples increased as the calcination temperature increased, the most efficient product in terms of the photoreduction duration of Cr(vi) was produced through the calcination process carried out at 450 °C, which reduced the concentration by more than 99% in 40 minutes.

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Posttranslational modifications play a crucial role in governing cellular functions and protein behavior. Researchers have implicated dysregulated posttranslational modifications in protein misfolding, which results in cytotoxicity, particularly in neurodegenerative diseases such as Alzheimer disease, Parkinson disease, and Huntington disease. These aberrant posttranslational modifications cause proteins to gather in certain parts of the brain that are linked to the development of the diseases.

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MXene-based composites in smart wound healing and dressings.

Nanoscale Adv

July 2024

Department of Biomedical Engineering, Faculty of Engineering and Natural Sciences, Istinye University Istanbul 34396 Turkey

MXenes, a class of two-dimensional materials, exhibit considerable potential in wound healing and dressing applications due to their distinctive attributes, including biocompatibility, expansive specific surface area, hydrophilicity, excellent electrical conductivity, unique mechanical properties, facile surface functionalization, and tunable band gaps. These materials serve as a foundation for the development of advanced wound healing materials, offering multifunctional nanoplatforms with theranostic capabilities. Key advantages of MXene-based materials in wound healing and dressings encompass potent antibacterial properties, hemostatic potential, pro-proliferative attributes, photothermal effects, and facilitation of cell growth.

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  • Advanced glycation end products (AGEs) are harmful compounds formed during the Maillard reaction, linked to serious health issues like diabetes and chronic inflammation.
  • The study explored the antiglycation properties of pistachio green hull (PGH) and pomegranate peel (PP) extracts, both rich in polyphenols, and compared their effectiveness to traditional antiglycation agents like vitamin B6, metformin, and EDTA.
  • Results showed that PGH and PP extracts significantly inhibited AGE formation, with PP demonstrating a stronger effect than PGH, suggesting their potential use in creating healthier food products.
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Lentil protein hydrolysates (LPH) and lentil protein hydrolysates cross-linked (LPHC) were grafted with gum Arabic (GA) through a wet Maillard reaction at 100°C for 2 h and called MLPH and MLPHC. The samples were assessed for absorption, degree of grafting (DG), surface hydrophobicity, antioxidant activity, molecular weight (MW) profile, chemical alteration, volatile compounds, functional and sensory properties. Results showed that Maillard grafting led to increase in absorption and DG (maximum value: MLPHC), and led to the reduction of the surface hydrophobicity and antioxidant activity (minimum value: MLPHC).

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This study aimed to investigate the effect of adding ficin-hydrolyzed wheat gluten at different levels (0%, 1%, 2%, 4%) on bread quality, and in vitro antioxidant activity before and after simulated gastrointestinal digestion. Our findings revealed that the incorporation of the generated wheat gluten hydrolysates (WGH) up to 4 g per 100 g flour positively affected the technological and physical-chemical characterizations of breads, including dough rheological properties, color, specific volume, and moisture. The texture profile analysis indicated reductions in hardness, springiness, and chewiness of the breads, and confirmed anti-staling properties during storage.

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In this research, ZSM-12 zeolite with six Si/Al ratios (20 to 320) was synthesized by a hydrothermal method and systematically investigated. The physicochemical properties of the synthesized nano zeolites were evaluated and compared by XRD, FE-SEM,ICP-AES, NH-TPD, BET, FT-IR, and TGA analyses. The results show that when the Si/Al ratio increases, the amount of microcrystals increases with the dominant competitive phase of cristobalite by decreasing the MTW phase.

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  • Adipose triglyceride lipase (ATGL) is a key enzyme involved in breaking down fats and is influenced by insulin; it also plays a role in inflammation and insulin resistance related to obesity and metabolic syndrome.
  • The study involved 100 participants, comparing 50 with obesity to 50 healthy individuals, measuring lipid profiles, insulin levels, and gene expression of ATGL in immune cells.
  • Results showed ATGL expression was higher in participants with obesity and metabolic syndrome, linked to inflammation and insulin resistance, indicating ATGL could be crucial in developing metabolic issues associated with obesity.
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In a stride towards sustainable solutions, this research endeavors to address the critical issue of water pollution heavy metals by coupling the power of magnetic nanotechnology, in combination with a green chemistry approach, to eliminate two noxious inorganic pollutants: chromium(vi) and nickel(ii) from aqueous environments. The synthesis of magnetite (FeO) nanoparticles was achieved using ferric chloride hexahydrate (FeCl·6HO) as a precursor, with the assistance of Lam. leaves extract, known for its remarkable salt-reducing properties.

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The presence of aflatoxins in food products can lead to health risks in human societies. Therefore, in the present study, the effect of yeast strains isolated from fermented products and titanium dioxide nanoparticles (TiO-NPs) was studied on aflatoxin reduction. Yeast strains were isolated from fermented products such as sweet fruits and dairy products and identified using biochemical, ascospore (testing by culture medium optimization V8 which is called V8NLF), and molecular methods.

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In this study, we synthesized manganese selenide under magnetic fields ranging from 0 to 800 gauss and investigated its optical, electrical, and magnetic properties. In the absence of a magnetic field, we observed the formation of MnSe nanorods. As the field strength increased, impurities arose.

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Lung cancer is indeed a major cause of cancer-related deaths worldwide. The development of tumors involves a complex interplay of genetic, epigenetic, and environmental factors. Epigenetic mechanisms, including DNA methylation (DNAm), histone modifications, and microRNA expression, play a crucial role in this process.

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Congenital myasthenic syndromes-5 (CMS5) is a rare autosomal recessive heterogeneous disorder, caused by pathogenic variants in the that lead to skeletal muscle weakness and abnormal fatigability. The onset is usually from birth to childhood. Disease-causing variants in the collagen-like tail subunit are the most explained etiology in synaptic CMS, causing defected acetylcholinesterase.

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Background And Aims: Real-time reverse-transcriptase polymerase chain reaction (real-time RT-PCR) is the gold standard test for diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, when the test result is near the detection limit of the assay the possibility of getting false positive or negative results is high. In addition, it might result in single target gene positive (STGP) results which should be interpreted with caution.

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  • This study compares demographic and clinical outcomes of hospitalized COVID-19 patients in Iran infected with different SARS-CoV-2 variants (Alpha, Delta, and Omicron).
  • It analyzes data from 760 confirmed cases between April 2021 and May 2022, focusing on factors like age, laboratory results, hospital stay duration, and ICU admissions.
  • The study found that although the Omicron variant led to less severe disease overall, older patients had longer hospital stays, highlighting their increased vulnerability to severe illness.
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