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The possible therapeutic role of intravenous lipid emulsion in acute aluminium phosphide poisoning: a randomized controlled clinical trial.
Toxicol Res (Camb)
June 2024
Forensic Medicine and Clinical Toxicology at Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Tanta University-Medical collages complex-Al-Geish Street-Tanta,Gharbia 31527, Egypt.
Article Synopsis
- Aluminum phosphide (ALP) is a highly toxic rodenticide with mortality rates between 70-100%, and there's currently no specific antidote for its poisoning.* -
- In this study, 64 patients with acute ALP poisoning received either intravenous lipid emulsion (ILE) alongside conventional treatment or just conventional treatment, allowing researchers to assess the efficacy and safety of ILE.* -
- Results showed that ILE improved survival time, arterial blood pressure, and metabolic status in patients, but it did not significantly reduce mortality rates or the need for intubation and ventilation.*