1 results match your criteria: "Tanshan Medical University[Affiliation]"
[Effect of tanshitone on prevention and treatment of retinoic acid induced osteoporosis in mice].
Zhongguo Zhong Yao Za Zhi
November 2010
Pharmacy Department, Tanshan Medical University, Tan'an 271016, China.
Objective: To observe the prevention and therapeutic effects of tanshitone (TAN) on retinoic acid induced osteoporosis in mice.
Method: The mice osteoporosis was induced by given retinoic acid intragastrically for two weeks. The histomorphological features of bone were observed and biochemical indexes in serum (Ca, P, ALP, TRAP, E2, BGP) were determined after the mice were given TAN at the dose of 40, 80, 160 mg x kg(-1) respectly.