A novel combined oxidative stress and extracellular matrix related predictive gene signature for keratoconus.

Keratoconus (KC) is an ectatic cornea disease with high prevalence and asymptomatic at early stage, leading to decreased visual acuity and even cornea transplantation. However, the etiology mechanism of keratoconus is still poorly understood. Oxidative stress (OS) and extracellular matrix (ECM) remodeling play critical roles in keratoconus development.

Molecularly Imprinted Nanozymes with Substrate Specificity: Current Strategies and Future Direction.

Molecular imprinting technology (MIT) stands out for its exceptional simplicity and customization capabilities and has been widely employed in creating artificial antibodies that can precisely recognize and efficiently capture target molecules. Concurrently, nanozymes have emerged as promising enzyme mimics in the biomedical field, characterized by their remarkable stability, ease of production scalability, robust catalytic activity, and high tunability. Drawing inspiration from natural enzymes, molecularly imprinted nanozymes combine the unique benefits of both MIT and nanozymes, thereby conferring biomimetic catalysts with substrate specificity and catalytic selectivity.

Design of judicial public opinion supervision and intelligent decision-making model based on Bi-LSTM.

Fuzzy preference modeling in intelligent decision support systems aims to improve the efficiency and accuracy of decision-making processes by incorporating fuzzy logic and preference modeling techniques. While network public opinion (NPO) has the potential to drive judicial reform and progress, it also poses challenges to the independence of the judiciary due to the negative impact of malicious public opinion. To tackle this issue within the context of intelligent decision support systems, this study provides an insightful overview of current NPO monitoring technologies.

Microscopic Mechanism of Coal Wetting-Dissolution under Surfactant-Assisted Acidification Conditions.

Coal wetting-acidification is a promising method to enhance the coal dust control and gas permeability. To elucidate the internal transformation process of coal wetting-dissolution, this study employs contact angle measurements, low-temperature nitrogen adsorption, scanning electron microscopy, and X-ray diffraction to investigate the wetting characteristics and pore structure changes of coal before and after treatment with acid and surfactant composite reagents. The interaction mechanisms between mineral dissolution and wetting-dissolution characteristics are explored.

[Effect and Mechanism of Water-soluble Chitosan Promoting Phytoremediation of Cd and/or Pb-contaminated Soils by L].

A pot experiment was conducted to investigate the growth response, concentration, and transportation characteristics of Cd and Pb in L. in four typical Cd/Pb-contaminated soils from northern and southern China with the addition of different levels of water-soluble chitosan （WSC）. The effect of WSC on physicochemical properties, Cd and Pb forms, and functional groups in contaminated soils was determined to clarify the internal mechanism of WSC promoting Cd and Pb accumulation by .

Research on autonomous walking performance and electromechanical characteristics of mining double-track chassis.

To study the autonomous walking performance and corresponding electromechanical characteristics of unmanned mining equipment under different slopes, turning radii, and ground conditions. Firstly, the autonomous walking systems based on PID, fuzzy PID, and BP PID, in this paper, are constructed, and then the electromechanical coupling simulation is carried out to analyse autonomous walking performance and electromechanical characteristics of mining double-track chassis under different working conditions. Finally, the feasibility of the autonomous walking system based on fuzzy PID is verified by the path-tracking experiment.

Sludge enrichment and intermittent gradient aeration: Modulating microbial communities for start-up of partial nitrification in a sequencing batch reactor (SBR).

A novel approach has been proposed integrating sludge enrichment with intermittent gradient aeration to achieve partial nitrification (PN). Results indicated that this method suppressed nitrite-oxidizing bacteria (NOB) activity while maintained ammonia-oxidizing bacteria (AOB) activity, achieving an 82.87 % nitrite accumulation rate (NAR) during startup.

Behavior and mechanism of element dissolution from albite by mannose: experimental and theorical study.

Context: In this work, the release behaviors of element from albite by mannose are studied experimentally, and the corresponding decomposition mechanism is explored from a microscopic perspective via density functional theory (DFT) calculations, with the aim of promoting the development of a microbial mineral weathering theory. The sodium, silicon and aluminium in albite are released into a solution under the action of mannose, and the release of these elements makes the surface of albite rough and decreases crystallinity and interplanar spacing of the crystal. The DFT results show that the hydroxyl H atom in mannose forms a hydrogen bond with the O atom on the surface of albite, thus causing the surface atoms to move away from their original positions, destroying the stability of the silica tetrahedron.

One-step hydrothermal synthesis of CQDs/TiO/NH-MIL-125 for efficient photocatalytic production of HO under visible light.

NH-MIL-125 and its derivatives are receiving more attention in various aspects of photocatalytic reactions, especially in the photocatalytic hydrogen peroxide (HO) production from water (HO) and oxygen (O), which is a promising and sustainable strategy. However, the generation of HO from NH-MIL-125 is far from satisfactory due to rapid photo-generated carriers recombination and poor surface electron transfer. In the work, the composite photocatalyst CQDs/TiO/NH-MIL-125 (C/T/NM) was designed for the first time by one-step hydrothermal method.

Gas migration control in goaf with double roof cutting and retaining roadway.

The behavior of gas migration in goaf under double roof cutting conditions directly influences the effectiveness of gas control measures. This study employs a combination of numerical simulation and field verification to investigate the patterns of gas migration and accumulation in goaf and to develop coordinated gas control methods under the conditions of double roof cutting and retained roadway. The results indicate that with double roof cutting, goaf permeability generally increases from the interior towards the exterior, with significantly higher porosity in the separation range compared to other areas.

Topological Defect-Regulated Porous Carbon Nanoribbon for High-Performance Potassium-Ion Batteries.

Potassium-ion batteries (PIBs) using carbonaceous anode materials have attracted a great deal of research interest. However, the large atomic size of potassium ions inevitably leads to huge volume expansion and the collapse of anodes during intercalation, which greatly hinders rate performance and cycling life. In this work, carbon nanotube-derived porous N-doped carbon nanoribbon (CNR) bundles are designed as an anode for PIBs.

Catalytic Advancements in NH Selective Catalytic Oxidation: The Impact of Cu-Induced Lattice Distortion in TiO Crystal Structure.

A series of x Cu-TiO obtained from the sol-gel method were tested for NH selective catalytic oxidation (NH-SCO). Its performance was higher than that of supported Cu/TiO-Im and solvent-free Cu/TiO-SF. The catalyst exhibits better water resistance at 300 °C.

Emodin Enhanced Microwave-Responsive Heterojunction with Powerful Bactericidal Capacity and Immunoregulation for Curing Bacteria-Infected Osteomyelitis.

Eradication of osteomyelitis caused by bacterial infections is still a major challenge. Microwave therapy has the inherent advantage of deep penetration in curing deep tissue infections. However, the antibacterial efficiency of sensitizers is limited by the weak energy of microwaves.

Intratumoral Transforming Boron Nanosensitizers for Amplified Boron Neutron Capture Therapy.

Boron neutron capture therapy (BNCT) is an advanced binary tumor-cell-selected heavy-particle radiotherapy used for treating invasive malignant tumors. However, its clinical applications have been impeded by the rapid metabolism and insufficient tumor-specific accumulation of boron agents. To tackle this issue, we develop a smart boron nanosensitizer (BATBN) capable of transforming its size in response to cancer biomarker for optimal balance between penetration and retention of boron-10 for BNCT.

Intelligent Fault Diagnosis of Hydraulic System Based on Multiscale One-Dimensional Convolutional Neural Networks with Multiattention Mechanism.

Hydraulic systems are critical components of mechanical equipment, and effective fault diagnosis is essential for minimizing maintenance costs and enhancing system reliability. In practical applications, data from hydraulic systems are collected with varying sampling frequencies, coupled with complex interdependencies within the data, which poses challenges for existing fault diagnosis algorithms. To solve the above problems, this paper proposes an intelligent fault diagnosis of a hydraulic system based on a multiscale one-dimensional convolution neural network with a multiattention mechanism (MA-MS1DCNN).

The Impacts of Volcanic Activity on Microbial Growth-A Simulation Experiment in the Qiliao Section in Shizhu County, Chongqing, China.

The impact of volcanic activity on microorganisms has always been a hot topic of discussion during geological history. Further studies are needed on the effects of volcanic activity on microbial growth in shale and the differences in nutrients provided by volcanic ash and other weathered rocks. This study's results indicated that TOC contents at the bottom of the shale layer are 1.

Ethane Triggered Gate-Opening in a Flexible-Robust Metal-Organic Framework for Ultra-High Purity Ethylene Purification.

Priority recognition separation of inert and larger ethane molecules from high-concentration ethylene mixtures instead of the traditional thermodynamic or size sieving strategy is a fundamental challenge. Herein, we report ethane triggered gate-opening in the flexible-robust metal-organic framework Zn(ad)(min), the 3-methylisonicotinic acid ligand can spin as a flexible gate when adsorbing the cross-section well-matched ethane molecule, achieving an unprecedented ethane adsorption capacity (62.6 cm g) and ethane/ethylene uptake ratio (3.

Load recognition of connecting-shaft rotor system under complex working conditions.

A method for qualitatively recognizing the load of the rolling equipment's connecting-shaft rotor system is proposed in this paper due to the complexity of rolling production conditions and the limitations of single source response signals. The method is oriented towards fusing the vibration and motor's current information. First, singular value decomposition and wavelet packet analysis are used to preprocess the two types of response signals.

Reconfiguring FeN sites through axial FeO clusters to enhance d-orbital electronic delocalization for improved oxygen reduction reaction.

Effectively controlling the electronic configuration of metal sites within single-atom catalysts (SACs) is essential for improving their oxygen reduction reaction (ORR) performance. Here, we construct hybrid catalysts featuring Fe single atoms and FeO clusters (Fe SACs/FeO@NHPC) to realize highly efficient ORR. Specifically, the Fe SACs/FeO@NHPC delivers a remarkable half-wave potential (E) of 0.