326,008 results match your criteria: "Taiwan; National Taiwan University Children's Hospital[Affiliation]"

Biomineralization reaction from nanosized calcium silicate: A new method for reducing dentin hypersensitivity.

J Dent Sci

January 2025

Department of Conservative Dentistry, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea.

Background/purpose: This study assessed the ability of experimental materials consisting of dicalcium silicate (DCS) and tricalcium silicate (TCS) with nanosized particles to form intratubular crystals under phosphate-buffered saline (PBS) and the effect on dentin permeability reduction.

Materials And Methods: By isolating the cervical part of the extracted premolars, 195 specimens were obtained. Two experimental materials (DCS/TCS and TCS) were applied to the dentin surface by brushing and stored in PBS (n = 65).

View Article and Find Full Text PDF

Background/purpose: COVID-19 vaccines are supplied at no-cost to residents as a measure to prevent comorbidities, fatalities, and the increased risk of community transmission, thus protecting public health systems. However, vaccine acceptance among cancer patients remained uncertain. This study aimed to elucidate the vaccination rates among oral cancer patients at a medical center in Taiwan.

View Article and Find Full Text PDF

Background/purpose: Salivary microbiome has become a surrogate indicator of oral disease due to its collective reservoirs and convenience in sampling. However, failed clinical trials often lead to wastes of resources, indicating a need for preclinical models. In this pilot study, we aimed to compare the salivary microbiome by metagenomics analysis before and after lysogeny broth culture for prospective translational studies.

View Article and Find Full Text PDF

Background/purpose: The relationship among chewing ability, food texture selection, and nutritional status in the elderly is well-known. This study tried to find the reliable biomarkers to predict the chewing ability and nutritional status of the elderly people.

Materials And Methods: Sixty-eight elderly subjects (mean age, 80.

View Article and Find Full Text PDF

Background/purpose: Orthodontic movement is often necessary for periodontally compromised patients to enhance esthetics, function, and long-term occlusal stability. However, the impact of orthodontic treatment immediately following the regeneration of intrabony defects on periodontal healing remains a topic of debate. The objective of this long-term case series study was to test the hypothesis that orthodontic treatment performed immediately after regenerative procedures for periodontal intrabony defects did not adversely affect periodontal healing.

View Article and Find Full Text PDF

Antimicrobial properties of bimetallic-containing mesoporous bioglass against .

J Dent Sci

January 2025

Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan.

Background/purpose: Various pulp-covering materials offer advantages in regenerative root canal treatment, but each has limitations, highlighting the need for more effective antibacterial strategies for pulp repair and regeneration. Mesoporous bioactive glasses (MBG) show significant biological activity, making them valuable in tissue/dental repair. Silver-incorporated MBG exhibits promising antibacterial effects against various bacteria; copper ions are crucial in regulating angiogenesis signals.

View Article and Find Full Text PDF

Background/purpose: Dentists often focus on masticatory performance (MP) rather than masticatory ability (MA) and treatment expectations when evaluating older adults. This study aimed to determine if MA aligns with MP and to explore influencing factors.

Materials And Methods: This cross-sectional study utilized a multi-stage stratified cluster sampling, including one thousand community-dwelling adults aged 60 and older.

View Article and Find Full Text PDF

Background/purpose: Oral mucosal lesions are associated with a variety of pathological conditions. Most deep-learning-based convolutional neural network (CNN) systems for computer-aided diagnosis of oral lesions have typically concentrated on determining limited aspects of differential diagnosis. This study aimed to develop a CNN-based diagnostic model capable of classifying clinical photographs of oral ulcerative and associated lesions into five different diagnoses, thereby assisting clinicians in making accurate differential diagnoses.

View Article and Find Full Text PDF

Background/purpose: Although clinical studies have suggested a link between non-axial forces and reduced longevity of cervical restorations, the underlying mechanisms require further numerical investigation. This in-silico study employed a cohesive zone model (CZM) to investigate interfacial damage in a cervical restoration subjected to different load directions.

Materials And Methods: A plane strain model of a maxillary premolar was established, with a wedge-shaped buccal cervical restoration.

View Article and Find Full Text PDF

Background/purpose: In general, improving oral health can reduce the risk of pneumonia. The purpose of this retrospective cohort study was to investigate the risk of pneumonia between cerebral palsy (CP) cohort and non-CP cohort as well as the association of pneumonia with the number of dental visits in CP patients in Taiwan.

Materials And Methods: We identified 10,544 patients who were diagnosed with CP between 2010 and 2019 from the Taiwan National Health Insurance Research Database.

View Article and Find Full Text PDF

Background/purpose: -2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (THSG) is a bioactive component in the Chinese herb Polygonum multiflorum, recognized for its anti-inflammatory and lipid-lowering properties. Human dental pulp stem cells (hDPSCs) have excellent capabilities in tooth regeneration, wound healing, and neural repair. The exosomes (Exo) released by hDPSCs contain bioactive molecules that influence cell proliferation, differentiation, and immune responses.

View Article and Find Full Text PDF

Background: : The metabolic by-product butyric acid of Gram-negative anaerobic bacteria can invoke pathological effects on periodontal cells resulting in inflammation and further destruction of periodontium. However, limited researches on the effects of butyric acid on cementoblasts were reported. Therefore, this study aimed to investigate the type of cell death in murine cementoblast (OCCM.

View Article and Find Full Text PDF

Background/purpose: The performance of intraoral scanners (IOSs) relies on the operator's skills. However, whether operator experience influences IOS accuracy remains unclear. This study investigated the effect of operator experience on the trueness accuracy and time-based efficiency of IOSs.

View Article and Find Full Text PDF

Novel early vertical ridge augmentation technique.

J Dent Sci

January 2025

School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.

Background/purpose: Multiple augmentation protocols are documented in the literature to rebuild the deficient alveolar ridge after tooth extraction; however, achieving adequate vertical augmentation remains the most challenging goal. This study demonstrated a novel surgical technique of early vertical ridge augmentation for post-dental extraction. This technique offers several biological and technical advantages regarding the timing of the procedure and its relative simplicity compared to other complex techniques.

View Article and Find Full Text PDF

Background/purpose: Osseointegration potential is greatly depended on the interaction between bone cells and dental implant surface. Since zirconia ceramic has a bioinert surface, functionalization of the surface with an organic compound allylamine was conducted to overcome its drawback of minimal interaction with the surrounding bone.

Materials And Methods: The zirconia surface was initially treated with argon glow discharge plasma (GDP), then combined with amine plasma at three different conditions of 50-W, 75-W and 85-W, to prepare the final samples.

View Article and Find Full Text PDF

Background/purpose: Studies have demonstrated a relation between hypercholesterolemia and development of apical periodontitis (AP), but the underlying mechanism is uncertain. 27-hydroxycholesterol (27HC), produced by cytochrome P450 27A1 (CYP27A1)-catalyzed hydroxylation of cholesterol, is known to possess pro-inflammatory activity. Felodipine is an anti-hypertensive agent able to inhibit CYP27A1.

View Article and Find Full Text PDF

Background/purpose: Different types of scanners are gradually used to produce digital dental casts in the current dental practice. This study tested the accuracy of the three desktop scanners and two intraoral scanners and evaluated whether the desktop scanners had higher precision than the intraoral scanners.

Materials And Methods: This study used the three desktop and two intraoral scanners to scan a standard dental cast 5 times.

View Article and Find Full Text PDF