Machine learning-driven prediction of medical expenses in triple-vessel PCI patients using feature selection.

Revascularization therapies, such as percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG), alleviate symptoms and treat myocardial ischemia. Patients with multivessel disease, particularly those undergoing 3-vessel PCI, are more susceptible to procedural complications, which can increase healthcare costs. Developing efficient strategies for resource allocation has become a paramount concern due to tightening healthcare budgets and the escalating costs of treating heart conditions.

ARTN and CCL23 predicted chemosensitivity in acute myeloid leukemia: an Olink proteomics approach.

Background: The standard "7 + 3" induction results in 30% of de novo acute myeloid leukemia (AML) patients not achieving complete remission (CR). We aimed to utilize the Olink platform to compare the bone marrow plasma proteomic profiles of newly diagnosed de novo AML patients who did and did not achieve CR following "7 + 3" induction treatment.

Methods: This prospective study included 43 untreated AML patients, stratified into CR (n = 29) and non-CR (n = 14) groups based on their response to "7 + 3" induction therapy.

Vitreomacular traction - a review.

Vitreomacular traction (VMT) is characterised by abnormal adhesion of the posterior cortical vitreous with the macula causing distortion of the foveal contour and associated with symptoms of reduction in visual acuity and/or metamorphopsia. This review article explores the pathophysiology, clinical features, diagnostic and treatment options for VMT. Advances in imaging modalities such as optical coherence tomography (OCT) have revolutionized the understanding of the vitreoretinal interface abnormalities and helps in monitoring the disease progression.

Noncryopexy versus cryopexy treatment during scleral buckling: a systematic review and meta-analysis.

Objectives: To evaluate the differences in surgical outcomes between scleral buckling (SB) with noncryopexy and cryopexy methods.

Methods: We systematically searched the Embase, Medline, Cochrane Library, and Scopus databases for randomized controlled trials (RCTs) published from their inception until January 1, 2024. A random-effects model was applied, and outcomes are presented as risk ratios (RRs) or standardized mean differences with 95% confidence intervals (CIs).

Population genetic structure of Uroteuthis edulis in the East China Sea based on the COI gene.

Background: Uroteuthis edulis is a significant economic cephalopod resource utilized by mainland China, Taiwan, and Japan. Understanding the population genetic structure of U.edulis is essential to evaluate the changes of its resource abundance.

Deep learning algorithms for predicting pathological complete response in MRI of rectal cancer patients undergoing neoadjuvant chemoradiotherapy: a systematic review.

Purpose: This systematic review examines the utility of deep learning algorithms in predicting pathological complete response (pCR) in rectal cancer patients undergoing neoadjuvant chemoradiotherapy (nCRT). The primary goal is to evaluate the performance of MRI-based artificial intelligence (AI) models and explore factors affecting their diagnostic accuracy.

Methods: The review followed PRISMA guidelines and is registered with PROSPERO (CRD42024628017).

Trust in scientists and their role in society across 68 countries.

Science is crucial for evidence-based decision-making. Public trust in scientists can help decision makers act on the basis of the best available evidence, especially during crises. However, in recent years the epistemic authority of science has been challenged, causing concerns about low public trust in scientists.

Exploring the utility of different bulking agents for speeding up the composting process of household kitchen waste.

Household kitchen waste (HKW) is produced in large quantity and its management is difficult due to high moisture content and complex organic matter. Aerobic composting of HKW is an easy, efficient, cost-effective and eco-friendly method. This study is designed to achieve a zero-waste concept and to convert HKW.

Long-term outcomes and lymph node metastasis following endoscopic resection with additional surgery or primary surgery for T1 colorectal cancer.

Optimal management of T1 colorectal cancer (CRC) remains controversial. This study compared the long-term outcomes of endoscopic resection with additional surgical resection (ER + ASR) versus primary surgical resection (PS) in patients with T1 CRC and identified risk factors for lymph node metastasis (LNM). This retrospective cohort study included 373 patients with T1 CRC who underwent ER + ASR or PS between January 2010 and December 2020 at a tertiary center in Taiwan.

Triadic balance and network evolution in predictive models of signed networks.

This paper introduces a novel approach for identifying dynamic triadic transformation processes, applied to five networks: three undirected and two directed. Our method significantly enhances the prediction accuracy of network ties. While balance theory offers insights into evolving patterns of triadic structures, its effects on overall network dynamics remain underexplored.

Perceptions of science, science communication, and climate change attitudes in 68 countries - the TISP dataset.

Science is integral to society because it can inform individual, government, corporate, and civil society decision-making on issues such as public health, new technologies or climate change. Yet, public distrust and populist sentiment challenge the relationship between science and society. To help researchers analyse the science-society nexus across different geographical and cultural contexts, we undertook a cross-sectional population survey resulting in a dataset of 71,922 participants in 68 countries.

Epidemiological feature of imported malaria in Taiwan during the 2014-to-2020 period.

Although the World Health Organization (WHO) certified Taiwan as being malaria-free in 1965, there are reports of a few imported cases each year by travelers who visit malaria-endemic areas. This study examined the epidemiology of imported malaria cases in Taiwan from 2014 to 2020, utilizing national surveillance data from the Taiwan Centers for Disease Control. Malaria cases were confirmed through the application of standard laboratory methods.

Low-dose dasatinib-induced chylothorax, pulmonary hypertension, and pericardial effusion in a patient with chronic myeloid leukemia: A case report and literature review.

Rationale: Chylothorax is a rare adverse effect that is associated with dasatinib, a tyrosine kinase inhibitor administered for chronic myeloid leukemia (CML) treatment. Most reported cases have described standard dosing. In this case report, we described a 43-year-old male patient with CML who developed chylothorax after 4 years of low-dose dasatinib therapy.

Longitudinal associations of flare and damage accrual in patients with systemic lupus erythematosus.

Objective: To estimate the prevalence of organ damage (damage) and flare and to examine longitudinal associations between flares and subsequent damage accrual, in patients with systemic lupus erythematosus (SLE).

Methods: Patients enrolled in the Asia Pacific Lupus Collaboration cohort with ≥3 years of prospectively captured data were studied. Flares were assessed at routine visits, while damage ((Systemic Lupus International Collaborating Clinics/American College of Rheumatology) Damage Index) was assessed annually.

Liquid crystal sensor for Cr(III)-citrate detection via interfacial coagulation.

Background: Trivalent chromium (Cr(III)) and its highly soluble carboxyl complexes, often discharged into the environment by industries such as electroplating, leather tanning, and textile manufacturing, present severe risks to human health and ecosystems due to their high toxicity. These compounds are notoriously difficult to detect and remove during wastewater treatment, as they can persist in aqueous environments. Consequently, there is a pressing need for the development of simple, cost-effective, and reliable methods for their detection, which can improve monitoring, facilitate timely interventions, and enhance environmental protection efforts.

Enhanced assessment of water quality for both nitrate and nitrite using engineered E. coli with para-aminobenzoic acid biosynthesis.

Background: Monitoring nitrate and nitrite levels in water is vital for protecting human health, aquatic ecosystems, and regulatory compliance. However, traditional detection methods often involve environmentally harmful chemicals. This study introduces a sustainable alternative by leveraging metabolically engineered E.

Negative Prognostic Factors and Clinical Improvement Prediction Modeling for ESWT in Calcific Shoulder Tendinitis Using Artificial Intelligence Techniques.

Background: The efficacy of extracorporeal shockwave therapy (ESWT) for treating shoulder calcific tendinitis can be influenced by various prognostic factors. This study aimed to identify prognostic factors associated with the failure of ESWT for symptom relief and to evaluate the predictive capability of the eXtreme Gradient Boosting (XGBoost) algorithm of artificial intelligence techniques in this context.

Methods: This retrospective study enrolled patients with persistent shoulder pain attributed to calcific tendinitis who underwent ESWT after failed conservative treatment between January 1998 and December 2022.

Characterizing the diabetes-induced pathological changes of the mouse lung by single-cell RNA sequencing.

Pulmonary disorders are exacerbated by high blood sugar, leading to a disordered immune defense and increased susceptibility to infection. Type 2 diabetes mellitus (T2D) is characterized by insulin resistance and inadequate insulin production. Mechanisms leading to pulmonary alternation due to T2D are not clear.

Dexlansoprazole acts as a disruptor of the aryl hydrocarbon receptor and ITE.

Dexlansoprazole, a proton pump inhibitor, is commonly used to treat gastro-oesophageal reflux disease and erosive esophagitis. The activated aryl hydrocarbon receptor (AhR) functions as a transcription factor by binding to the aryl hydrocarbon response element (AHRE) of its target genes, with cytochrome P450 (CYP) 1A1 being the most well-known target. In this study, we demonstrated that dexlansoprazole stimulates AhR activity, leading to increased CYP1A1 expression.

Identification and Validation of SPP1 as a Potential Biomarker for COPD Through Comprehensive Bioinformatics Analysis.

Background: Chronic Obstructive Pulmonary Disease (COPD) is a challenging respiratory condition characterized by persistent airflow limitation and progressive lung function decline. The identification of robust biomarkers is crucial for early diagnosis, monitoring disease progression, and guiding therapeutic strategies.

Methods: In this study, we employed a comprehensive bioinformatics approach utilizing multiple Gene Expression Omnibus (GEO) datasets to identify potential COPD biomarkers.

Scopolamine affects fear learning and social recognition in adult zebrafish.

Scopolamine is the secondary metabolite of the Datura stramonium and act as a muscarinic receptor antagonist. Previous studies showed that scopolamine caused attention and memory deficit. However, the effects of scopolamine on specific cognitive functions, such as fear learning and social recognition, remain poorly understood.

Geographical and Socioeconomic Disparities in Substance and Opioid Use Disorders Among Inflammatory Bowel Disease Hospitalizations in the United States From the National Inpatient Sample.

We compared substance use disorder (SUD) prevalence among adult inflammatory bowel disease (IBD) hospitalizations with non-IBD controls from the 2016-2018 National Inpatient Sample, assessing correlations with demographics, socioeconomic status, geographic regions, depression, and anxiety. The primary aim focused on SUD, defined as substance abuse or dependence (: F10-F19) excluding unspecified use or remission, among hospitalizations documenting IBD (Crohn's disease or ulcerative colitis; : K50-51) as one admitting diagnosis (IBD-D). The prevalence of SUD among hospitalizations with and without IBD was compared.