Torsion and ruptured ovarian cystadenocarcinoma with internal bleeding complicated with retroperitoneal hematoma after tumor transection: A case report.

Rationale: Ovarian tumor torsion is a critical gynecological emergency, predominantly affecting women of reproductive age, with benign teratomas being the most common culprits. In contrast, malignant ovarian tumors, such as mucinous cystadenocarcinoma, infrequently present with torsion due to their invasive and angiogenic characteristics. The occurrence of torsion in malignant tumors complicates diagnosis and management, particularly when associated with complications like congestion, infarction, and internal bleeding.

AI-Driven Innovations for Early Sepsis Detection by Combining Predictive Accuracy With Blood Count Analysis in an Emergency Setting: Retrospective Study.

Background: Sepsis, a critical global health challenge, accounted for approximately 20% of worldwide deaths in 2017. Although the Sequential Organ Failure Assessment (SOFA) score standardizes the diagnosis of organ dysfunction, early sepsis detection remains challenging due to its insidious symptoms. Current diagnostic methods, including clinical assessments and laboratory tests, frequently lack the speed and specificity needed for timely intervention, particularly in vulnerable populations such as older adults, intensive care unit (ICU) patients, and those with compromised immune systems.

Observation of Robust Compressed CuO Octahedra and Exotic Spin Structure in CaCuFeO.

CuO octahedra usually show elongated distortion, leading to active orbitals and planar exchange interactions, while compressed CuO octahedra with active orbitals and unidirectional exchange interactions are exceptionally rare. Here, we design and synthesize a new frustrated antiferromagnet CaCuFeO through a high-pressure and high-temperature approach, in which robust compressed CuO octahedra are realized, separating the FeO sheets that comprise zigzag spin ladders. Magnetic susceptibility and specific heat measurements exhibit a long-range antiferromagnetic order below the Néel temperature of 165 K, which is further confirmed by neutron diffraction.

Acceptance of Virtual Reality Training for Chemotherapy Administration Among Nursing Students.

Virtual reality technology offers an extended and repeatable environment for delivering digital learning and training. This study investigated the acceptance of a smartphone virtual reality training program among nursing students for chemotherapy administration using a modified Technology Acceptance Model. The teaching materials for the chemotherapy administration process were designed using smartphone virtual reality to provide prelicensure students with an opportunity to learn procedural steps in a controlled, risk-free environment.

Direct Frequency Comb Cavity Ring-Down Spectroscopy Using Vernier Filtering.

We present direct frequency comb cavity ring-down spectroscopy with Vernier filtering as a straightforward approach to sensitive and multiplexed trace gas detection. The high finesse cavity acts both to extend the interaction length with the sample and as a spectral filter, alleviating the need for dispersive elements or an interferometer. In this demonstration, a free running interband cascade laser was used to generate a comb centered at 3.

Nanophotonic inspection of deep-subwavelength integrated optoelectronic chips.

Artificial nanostructures with ultrafine and deep-subwavelength features have emerged as a paradigm-shifting platform to advanced light-field management, becoming key building blocks for high-performance integrated optoelectronics and flat optics. However, direct optical inspection of integrated chips remains a missing metrology gap that hinders quick feedback between design and fabrications. Here, we demonstrate that photothermal nonlinear scattering microscopy can be used for direct imaging and resolving of integrated optoelectronic chips beyond the diffraction limit.

Secondary metabolites of Alternaria alternate appraisal of their SARS-CoV-2 inhibitory and anti-inflammatory potentials.

This study identifies the secondary metabolites from Alternaria alternate and evaluates their ACE-2: Spike RBD (SARS-CoV-2) inhibitory activity confirmed via immunoblotting in human lung microvascular endothelial cells. In addition, their in vitro anti-inflammatory potential was assessed using a cell-based assay in LPS-treated RAW 264.7 macrophage cells.

Protocol for oral fecal gavage to reshape the gut microbiota in mice.

Fecal microbiota transplantation (FMT) is clinically applied, while oral FMT (oral fecal gavage [OFG]) is preferred for experimental mice. Here, we present a protocol for OFG in antibiotic-pretreated mice, demonstrating the progressive, time-dependent evolution of the gut microbiota in the recipients. We describe steps for fecal sample collection and preparation procedures, oral gavage, and monitoring gut microbiota changes.

Dose-response analysis of music intervention for improving delirium in intensive care unit patients: A systematic review and meta-analysis.

Background: Delirium is a common and severe condition among adult intensive care unit (ICU) patients. Music intervention, as a non-pharmacological approach, has the potential to reduce delirium, but the optimal dosage and type of intervention remain unclear.

Aim: To explore the effects of music intervention at different doses and types on reducing delirium in ICU patients.

Effects of mirror therapy on motor and functional recovery of the upper extremity in subacute stroke: Systematic review and meta-analysis.

Objective: To review and synthesize existing evidence on the effect of mirror therapy (MT) on motor and functional recovery and the effect of unimanual and bimanual MT in individuals with subacute stroke.

Methodology: PubMed, Physiotherapy Evidence Database, Cochrane, and Airiti Library were searched for relevant studies. Randomized and pilot randomized controlled trials comparing MT with sham MT or conventional therapy were included.

Distinct Behavioural and Brain Response Profiles Between Arithmetic Word Problem Solving and Sentence Comprehension in Third and Fourth Graders.

Word problems are essential for math learning and education, bridging numerical knowledge with real-world applications. Despite their importance, the neural mechanisms underlying word problem solving, especially in children, remain poorly understood. Here, we examine children's cognitive and brain response profiles for arithmetic word problems (AWPs), which involve one-step mathematical operations, and compare them with nonarithmetic word problems (NWPs), structured as parallel narratives without numerical operations.

Comprehensive Characterization of Overt Myelofibrosis in an Asian Cohort: Phenotype, Mutation Landscape and Discordance Among Scoring Systems.

Various prognostic scoring systems in myelofibrosis (MF) have been developed to guide clinical decision-making in MF. However, discrepancies between different scoring systems for individual patients remain poorly understood, which can result in conflicting treatment recommendations. Moreover, data regarding there applicability in Asian populations remain scarce.

Nonparametric Path-Specific Effects on a Survival Outcome Through Multiple Time-to-Event Mediators.

A causal mediation model with multiple time-to-event mediators is exemplified by the natural course of human disease marked by sequential milestones with a time-to-event nature. For example, from hepatitis B infection to death, patients may experience intermediate events such as liver cirrhosis and liver cancer. The sequential events of hepatitis, cirrhosis, cancer, and death are susceptible to right censoring; moreover, the latter events may preclude the former events.

Enhancing surface energy and characterizing optical properties of ultra-high translucency zirconia via an innovative heat treatment process.

Purpose: Ultra-high translucency zirconia (UT-Zr) is known for its high esthetic quality; however, its inert surface results in low hydrophilicity and surface energy (SE). To address this limitation, this study proposes an innovative zirconia heat treatment process (ZHTP) and aims to evaluate the effects of ZHTP on the surface characteristics of UT-Zr, offering a novel and practical approach for surface pretreatment in dental practice.

Material And Methods: The plate-shaped UT-Zr samples were fabricated.

Assessment of delirium in Indonesian pediatric intensive care unit: a psychometric evaluation of the Cornell Assessment of Pediatric Delirium.

Unlabelled: This study has the objective to translate the Cornell Assessment of Pediatric Delirium (CAPD) into Indonesian and evaluate the psychometric properties and diagnostic accuracy of the Indonesian version of the CAPD (I-CAPD) in identifying delirium in critically ill children. This prospective methodological study was conducted between January and April 2024 in a 6-bed pediatric intensive care unit (PICU). In total, 90 children aged 0-18 years hospitalized in the PICU were included.

Mediating roles of weight stigma and physical activity avoidance in the associations between severity of gaming disorder and levels of physical activity among young adults.

Background And Aims: There are limited data regarding associations between gaming disorder and physical activity (PA). The present study investigated the direct association between these two variables and assessed the potentially mediating roles of PA avoidance and two types of weight stigma (i.e.

Development and Validation of the Scale of Hypoglycemia Self-Care Behavior in Type 2 Diabetes.

Background: Inappropriate dietary, exercise, and medication self-care behaviors among persons with diabetes can easily trigger hypoglycemia. Clinically, it is necessary to quickly identify high-risk groups for hypoglycemic events to provide targeted hypoglycemia education. However, there is currently a lack of precise tools to assess self-care behaviors related to hypoglycemia.

Apple Vision Pro-guided Laparoscopic Radio Frequency Ablation for Liver Tumors: The Pioneer Experience.

This study evaluates the feasibility of Apple Vision Pro goggles as an augmented reality (AR) surgical navigation tool for laparoscopic-assisted ultrasound-guided radiofrequency ablation (RFA) of liver tumors. Traditional RFA is effective but challenging due to the integration of multiple imaging modalities. The primary aim of this research is to assess how Vision Pro goggles can enhance the surgical navigation process during RFA, improving tumor localization and the overall effectiveness of the procedure.

Clinical Characteristics of Snakebite Envenomings in Taiwan.

Snakebite envenomings continue to represent a major public health concern in Taiwan because of the presence of various venomous snakes whose habitats intersect with human activities. This review provides a comprehensive analysis of the clinical characteristics, complications, and management strategies associated with snakebite envenomings in Taiwan. Taiwan is inhabited by six principal venomous snakes: , , , , , and , each presenting distinct clinical challenges.

Lipoprotein Signal Peptide as Adjuvants: Leveraging Lipobox-Driven TLR2 Activation in Modern Vaccine Design.

Toll-like receptor 2 (TLR2) signaling is a pivotal component of immune system activation, and it is closely linked to the lipidation of bacterial proteins. This lipidation is guided by bacterial signal peptides (SPs), which ensure the precise targeting and membrane anchoring of these proteins. The lipidation process is essential for TLR2 recognition and the activation of robust immune responses, positioning lipidated bacterial proteins as potent immunomodulators and adjuvants for vaccines against bacterial-, viral-, and cancer-related antigens.

Digital Mini-LED Lighting Using Organic Thin-Film Transistors Reaching over 100,000 Nits of Luminance.

This paper demonstrates the use of organic thin-film transistors (OTFTs) to drive active digital mini light-emitting diode (mini-LED) backlights, aiming to achieve exceptional display performance. Our findings reveal that OTFTs can effectively power mini-LED backlights, reaching brightness levels exceeding 100,000 nits. This approach not only enhances image quality but also improves energy efficiency.

Effects of Pickleball Intervention on the Self-Esteem and Symptoms of Patients with Schizophrenia.

Schizophrenia is classified by the World Health Organization (WHO) as one of the top ten diseases contributing to the global medical economic burden. Some studies have pointed out that exercise is effective for physical and mental health, as well as cognition. We hypothesized that participation in pickleball intervention would lead to improved self-esteem and reduced psychiatric symptoms in schizophrenia patients.

Long-Term Stability and Osteogenic Activity of Recycled Polysulfone-Calcium Silicate Bone Implants In Vitro.

Environmental protection issues have received widespread attention, making material recycling increasingly important. The upcycling of polysulfone (PSF) medical waste, recognized as a high-performance plastic with excellent mechanical properties, deserves promotion. While PSF is suitable for use as an orthopedic implant material, such as internal fixation, its osteogenesis capabilities must be enhanced.