325,801 results match your criteria: "Taiwan; Duke Clinical Research Institute[Affiliation]"
Medicina (Kaunas)
December 2024
Department of Pharmacy, Tajen University, Pingtung 907, Taiwan.
: This study aimed to illustrate a novel method for improving presbyopia by drinking cassiae tea. : A total of 425 eyes from 425 participants (aged 52.5 ± 9.
View Article and Find Full Text PDFMedicina (Kaunas)
December 2024
Division of Gastroenterology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, No. 325, Section 2, Chenggong Road, Neihu District, Taipei City 114202, Taiwan.
Ingestion of foreign bodies is a prevalent issue in clinical practice, with fish bones being the predominant cause. While the upper gastrointestinal tract is commonly affected, small intestine impactions pose significant diagnostic challenges due to nonspecific symptoms and lack of awareness of foreign body ingestion. Herein, we describe a case presenting with recurrent, unexplained abdominal pain and hematochezia.
View Article and Find Full Text PDFMedicina (Kaunas)
December 2024
Graduate Institute of Business Administration, Fu Jen Catholic University, New Taipei City 242, Taiwan.
The rising prevalence of myopia is a significant global health concern. Atropine eye drops are commonly used to slow myopia progression in children, but their long-term use raises concern about intraocular pressure (IOP). This study uses SHapley Additive exPlanations (SHAP) to improve the interpretability of machine learning (ML) model predicting end IOP, offering clinicians explainable insights for personalized patient management.
View Article and Find Full Text PDFMedicina (Kaunas)
December 2024
Department of Pharmacy, Kaohsiung Show Chwan Memorial Hospital, Kaohsiung 821, Taiwan.
: The relationship between pregnancy complications and the risk of gynecological and breast cancer remains inconclusive, with limited research available. This study aimed to determine whether pregnancy complications, including preeclampsia, gestational diabetes mellitus (GDM), large for gestational age (LGA), or intrauterine growth restriction (IUGR) are associated with the development of endometrial cancer (EC), ovarian cancer (OC), or breast cancer (BC). : This was a population-based case-control study linked to the National Health Insurance Research Database from 2008 to 2020, using ICD codes to identify parous gynecological cases (n = 6714).
View Article and Find Full Text PDFMicroorganisms
January 2025
Graduate Institute of Human Resource and Knowledge Management, National Kaohsiung Normal University, Kaohsiung 802561, Taiwan.
Vancomycin-intermediate (VISA) is a multi-drug-resistant pathogen of significant clinical concern. Various strains can cause infections, from skin and soft tissue infections to life-threatening conditions such as bacteremia and pneumonia. VISA infections, particularly bacteremia, are associated with high mortality rates, with 34% of patients succumbing within 30 days.
View Article and Find Full Text PDFMicroorganisms
January 2025
Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Healthcare-associated infections (HAIs) significantly increase morbidity, mortality, length of hospital stays, and costs, particularly among ICU patients. Despite standard interventions, catheter-associated urinary tract infections (CAUTI) and central line-associated bloodstream infections (CLABSI) remain major HAI contributors. This study evaluated the efficacy of daily 2% chlorhexidine gluconate (CHG) bathing in reducing HAI incidence, specifically CAUTI, CLABSI, and multidrug-resistant organisms (MDROs), in a 20-bed ICU at a regional hospital.
View Article and Find Full Text PDFMicroorganisms
December 2024
Department of Aquaculture, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.
Aquaculture, a vital industry supplying a significant portion of the world's seafood, faces challenges such as the deterioration of the aquaculture environment. The objective of this study was to isolate and identify microorganisms with the capacity to eliminate nitrite in water from shrimp ponds and evaluate their potential as probiotics to improve water quality. Additionally, the study also determines the ideal conditions for the probiotic to effectively reduce nitrite-N and ammonia-N.
View Article and Find Full Text PDFMicromachines (Basel)
December 2024
Department of Biomedical Engineering, National Taiwan University, No. 1, Sec. 1, Jen-Ai Road, Taipei City 10051, Taiwan.
The authors wish to make a change to the published paper [...
View Article and Find Full Text PDFMicromachines (Basel)
January 2025
Department of Biomechatronics Engineering, National Taiwan University, Taipei 106319, Taiwan.
Silicon carbide (SiC) has significant potential as a third-generation semiconductor material due to its exceptional thermal and electronic properties, yet its high hardness and brittleness make processing costly and complex. This study introduces ultraviolet laser ablation as a method for direct SiC material removal, investigating the effects of varying scanning speeds on surface composition, hardness, and ablation depth. The results indicate optimal processing speeds for the Si and C faces at 200 mm/s and 100 mm/s, respectively.
View Article and Find Full Text PDFMicromachines (Basel)
December 2024
Taiwan Instrument Research Institute, National Applied Research Laboratories, Hsinchu 300092, Taiwan.
The development of bionic organ-on-a-chip technology relies heavily on advancements in in situ sensors and biochip packaging. By integrating precise biological and fluid condition sensing with microfluidics and electronic components, long-term dynamic closed-loop culture systems can be achieved. This study aims to develop biocompatible heterogeneous packaging and laser surface modification techniques to enable the encapsulation of electronic components while minimizing their impact on fluid dynamics.
View Article and Find Full Text PDFMicromachines (Basel)
December 2024
Department of Electrical Engineering, Chinese Culture University, Taipei 11114, Taiwan.
Based on additive manufacturing via photopolymerization, this study combines polymer-dispersed liquid crystal (PDLC) technology with 3D printing technology to produce tunable micro-optical components with switchable diffraction or focusing characteristics. The diffraction grating and Fresnel zone plate are the research targets. Their structures are designed and simulated to achieve expected optical functions.
View Article and Find Full Text PDFAntibiotics (Basel)
January 2025
Department of Laboratory Medicine and Biotechnology, Tzu Chi University, Hualien 970374, Taiwan.
Background: Increasing evidence shows that () largely affects colorectal cancer (CRC) growth and progression; therefore, the inhibition of intratumoral may be one realistic approach to combat CRC. Although antibiotics are helpful in eliminating bacteria, the major problem remains the rise of potential antibiotic-resistant strains and antibiotic-associated adverse effects. Currently, bacteriophage therapy has gained interest because of its high selectivity to bacterial hosts and may become a realistic approach in treating bacteria-associated cancers.
View Article and Find Full Text PDFAnimals (Basel)
January 2025
Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand.
Coffee cherry pulp (CCP) is a by-product of coffee bean production. CCP contains amounts of phenolic compounds that are beneficial for animals. This study evaluated the impact of coffee cherry pulp extract (CCPE) supplementation on growth performance, meat quality, carcass characteristics, serum biochemistry, cecum microbial population, intestinal morphology, and immune and antioxidant responses of broilers.
View Article and Find Full Text PDFAnimals (Basel)
January 2025
Key Laboratory of Fujian-Taiwan Animal Pathogen Biology, College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
is a zoonotic parasite that causes gastrointestinal diseases in both humans and animals. To evaluate the prevalence and genetic diversity of in black goats, we collected 539 fecal samples from nine districts in Fujian Province, China. The presence of was confirmed through nested PCR targeting the SSU rRNA gene, and genotyping was performed at the beta-giardin, glutamate dehydrogenase, and triosephosphate isomerase loci.
View Article and Find Full Text PDFCancers (Basel)
January 2025
Division of Colorectal Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung 40705, Taiwan.
: Colorectal cancer (CRC) is the third most common cancer worldwide, with colon cancer accounting for approximately 60% of all CRC cases. Surgery remains the primary and most effective treatment. Robotic-assisted surgery (RAS) has emerged as a promising approach for colon cancer resection.
View Article and Find Full Text PDFCancers (Basel)
January 2025
Division of Hematology-Oncology, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung 82445, Taiwan.
Background/objectives: The aim of this study is to assess the effectiveness of cetuximab combination therapy in patients with recurrent or metastatic head and neck cancer treated at a hospital in Southern Taiwan.
Methods: This study analyzed a retrospective cohort of 67 patients who were treated between January 2020 and May 2024 with two cetuximab regimens, cetuximab combined with cisplatin and 5-Fu, which were administered every four weeks during hospitalization (CPF4) and every two weeks as outpatient treatment (CPF2), respectively. The clinical outcomes, including overall survival and progression-free survival (PFS), were compared across the treatment regimens and age groups using Kaplan-Meier survival curves and Cox proportional hazard models.
Cancers (Basel)
January 2025
Department of General Surgery, Chang Gung Transplantation Institute, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan 33302, Taiwan.
Background: Liver transplantation (LT) is a promising treatment option for patients with hepatocellular carcinoma (HCC) comorbid with cirrhosis. However, HCC with portal vein tumor thrombosis (PVTT) remains an absolute contraindication for LT. This study aimed to analyze the outcomes of LT in patients with HCC plus portal vein thrombosis and further evaluate the impact of PVTT on the long-term outcomes of patients.
View Article and Find Full Text PDFCancers (Basel)
January 2025
Graduate Institute of Biomedical Sciences, China Medical University, Taichung 404333, Taiwan.
Background: This study aimed to investigate the polymorphic genotypes of rs937282, rs937283, rs2279744, and rs769412, as well as the combined effects of genotypes and environmental factors on RCC susceptibility.
Methods: A total of 135 RCC patients and 590 controls were recruited for genotyping using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. Quantitative PCR was performed to assess MDM2 mRNA levels among 30 healthy individuals and 22 RCC patients.
Children (Basel)
January 2025
Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung 83301, Taiwan.
Background/objectives: This cohort study aimed to establish a correlation between salivary cytokines and retinopathy of prematurity (ROP) in premature neonates. Additionally, we sought to identify a minimally invasive method for cytokine detection in this population.
Methods: We recruited premature neonates born at less than 34 weeks gestational age (GA), with no history of maternal or neonatal infections.
Children (Basel)
January 2025
Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.
Background: Argonautes (AGOs) are a type of protein that degrade specific messenger RNAs, consequently reducing the expression of a specific gene. These proteins consist of small, single-stranded RNA or DNA and may provide a route for detecting and silencing complementary mobile genetic elements. In this research, we investigated which AGO(s) were involved in Kawasaki disease (KD).
View Article and Find Full Text PDFBiomedicines
January 2025
Program in Molecular Medicine, College of Life Sciences, National Yang Ming Chiao Tung University, Taipei 11221, Taiwan.
In the original publication [...
View Article and Find Full Text PDFBiomedicines
January 2025
Department of Urology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien 97002, Taiwan.
The current study aimed to investigate the clinical comorbidities and urodynamic characteristics of a large cohort of women with dysfunctional voiding (DV) validated on a videourodynamic study (VUDS). Women who presented with VUDS-confirmed DV from 1998 to 2022 were retrospectively analyzed. Data on clinical symptoms, VUDS findings, and medical comorbidities including medical illness and previous surgical history were recorded and examined.
View Article and Find Full Text PDFBiomedicines
January 2025
Department of Mechanical Engineering, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.
: Cold atmospheric plasma (CAP) has been demonstrated as an adjustable device to generate various combinations of short-lived reactive oxygen and nitrogen species (RONS) and as a promising appliance for cancer therapy. This study investigated the effects of direct and indirect treatments of Argon-based CAP to cancer cells (A2058, A549, U2OS and BCC) and fibroblasts (NIH3T3 and L929) on cell viability. We also aimed to understand whether plasma-generated RONS were involved in this process using genetic evidence.
View Article and Find Full Text PDFBiomedicines
January 2025
Departments of Neurosurgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, No. 707, Sec. 3, Zhongyang Rd., Hualien City 970, Hualien County, Taiwan.
: To determine whether epidural electrical stimulation (EES) improves sensory recovery and walking function in patients with chronic spinal cord injury (SCI) with a grade on the American Spinal Cord Injury Association impairment scale (AIS) of C or D at the cervical level. : Three individuals with cervical-level chronic AIS D SCI were enrolled in the study. The mean injury duration and age were 4.
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