An Eye-Tracking-Based Investigation on the Principle of Closure in Logo Design.

This study employs subjective evaluation and eye movement experiments to explore the application and conveyance of logo graphics design, which conforms to the Gestalt principle of closure, to understand the psychological process of this principle in the perception of a logo. The study found that there is no significant difference between completely enclosed logos and unenclosed ones that conform to the principle of closure in their influence on sightline behavior due to the effects of closure, but the subjective evaluation favors unenclosed logos as more attractive and comfortable to perceive, which agrees with modern logo design trends. In addition, the sightline distribution of the image-type logos is more scattered and has the most extended fixation duration.

Revisiting the female germline cell development.

The formation of the female germline is the fundamental process in most flowering plants' sexual reproduction. In , only one somatic cell obtains the female germline fate, and this process is regulated by different pathways. Megaspore mother cell (MMC) is the first female germline, and understanding MMC development is essential for comprehending the complex mechanisms of plant reproduction processes.

New perspectives on djulis ( Koidz.) and its potential application in functional food.

Djulis ( Koidz.) is an endemic cereal plant to Taiwan that has been cultivated by Taiwanese aborigines for hundreds of years. Djulis Djulis is a well-known ruby cereal because it contains betanin and exhibits strong antioxidant activity.

Do meteorological variables impact air quality differently across urbanization gradients? A case study of Kaohsiung, Taiwan, China.

Air pollution has become a major challenge to global urban sustainable development, necessitating urgent solutions. Meteorological variables are key determinants of air quality; however, research on their impact across different urban gradients remains limited, and their mechanisms are largely unexplored. This study investigates the dynamic effects of meteorological variables on air quality under varying levels of urbanization using Kaohsiung City, Taiwan, as a case study.

Highly sensitive non-enzymatic glucose sensing using Ni nanowires and graphene thin film on the gate area of extended gate electric double-layer field-effect transistor.

This study presents an innovative glucose detection platform, featuring a highly sensitive, non-enzymatic glucose sensor. The sensor integrates nickel nanowires and a graphene thin film deposited on the gate region of an extended-gate electric double-layer field-effect transistor (EGEDL-FET). This unique combination of materials and device structure enables superior glucose sensing performance.

Light-Programmable g-CN Microrobots with Negative Photogravitaxis for Photocatalytic Antibiotic Degradation.

Microrobots enhance contact with pollutants through their movement and flow-induced mixing, substantially improving wastewater treatment efficiency beyond traditional diffusion-limited methods. g-CN is an affordable and environmentally friendly photocatalyst that has been extensively researched in various fields such as biomedicine and environmental remediation. However, compared to other photocatalytic materials like TiO and ZnO, which are widely used in the fabrication of micro- and nanorobots, research on g-CN for these applications is still in its early stages.

Detecting autism in children through drawing characteristics using the visual-motor integration test.

This study introduces a novel classification method to distinguish children with autism from typically developing children. We recruited 50 school-age children in Taiwan, including 44 boys and 6 girls aged 6 to 12 years, and asked them to draw patterns from a visual-motor integration test to collect data and train deep learning classification models. Ensemble learning was adopted to significantly improve the classification accuracy to 0.

Mothers' experiences as legal guardian of children's phlebitis during hospitalization in Indonesia: A phenomenological study.

Background: Peripheral intravenous catheter (PIVC) insertion is a common procedure performed by nurses for hospitalized children, but phlebitis-an inflammation of the vein-is a frequent complication. The response of the mother, as the child's primary caregiver, plays a key role in the healing process when phlebitis occurs.

Objective: This study aimed to explore mothers' experiences and perceptions regarding the occurrence and management of phlebitis in their children during hospitalization.

Challenges and support factors in managing type 2 diabetes among pregnant women in Thailand: A convergent mixed-methods study.

Background: Sociocultural and behavioral factors have a multifaceted impact on maternal health. In Thailand, cultural influences significantly shape behaviors of diabetes self-management in women. However, the experience of self-managing diabetes in pregnant women with preexisting Type 2 Diabetes Mellitus (T2DM) remains unclear.

Honduran nursing care to pressure injuries in patients with invasive mechanical ventilation: A qualitative study.

Background: Although substantial evidence exists regarding the treatment of pressure ulcers, there is a lack of studies demonstrating a comprehensive nursing approach for managing pressure ulcers in the ICU, particularly among patients with invasive mechanical ventilation from developing countries like Honduras. This gap in research is significant as the risk and impact of pressure ulcers on health recovery cannot be disregarded.

Objective: This study aimed to analyze Honduran nursing care for pressure ulcers in patients with invasive mechanical ventilation admitted to Intensive Care Units.

Impact of Leading Line Composition on Visual Cognition: An Eye-Tracking Study.

Leading lines, a fundamental composition technique in photography, are crucial to guiding the viewer's visual attention. Leading line composition is an effective visual strategy for influencing viewers' cognitive processes. However, in-depth research on the impact of leading line composition on cognitive psychology is lacking.

Second-line treatment patterns and outcomes in advanced HCC after progression on atezolizumab/bevacizumab.

Background & Aims: Atezolizumab/bevacizumab (A/B) is now a standard first-line treatment for advanced hepatocellular carcinoma (HCC), but the optimal second-line regimen is not known. We evaluated real-world treatment patterns and outcomes to investigate factors associated with post-progression survival (PPS).

Methods: In this multicenter, international, retrospective study, we examined clinical characteristics and outcomes of patients with advanced HCC who progressed on first-line A/B.

Durvalumab, Tremelimumab, and Platinum Chemotherapy in Mutation-Positive NSCLC: An Open-Label Phase 2 Trial (ILLUMINATE).

Introduction: -mutant NSCLC is associated with low mutation burden and low levels of PD-L1 expression. We conducted a phase 2 trial to determine the efficacy of durvalumab, tremelimumab, and platinum-pemetrexed in mutant NSCLC after progression with EGFR tyrosine kinase inhibitors (TKIs).

Methods: Participants were treated with induction durvalumab, tremelimumab, and platinum-pemetrexed, followed by durvalumab-pemetrexed maintenance.

Spatio-temporal patterns of tigers in response to prey species and anthropogenic activities.

Understanding factors influencing the spatio-temporal patterns of apex predators is prerequisite for their conservation. We studied space use and diel activity of tigers () in response to prey availability and anthropogenic activities with trail cameras in Nepal during December 2022-March 2023. We used hierarchical occupancy models to evaluate how prey availability (space use of prey species) and anthropogenic activities (number of humans and livestock) contributed to the tigers' space use, while accounting for landscape effects on their detection probability.

The Effects of Blue Light on Locomotion and Cognition in Early Adult Drosophila melanogaster.

Artificial light sources, particularly blue light, have raised concerns about their impact on biological health and behavior. In this study, we explored the effects of blue light on the locomotion and cognitive functions of early adult Drosophila melanogaster. Our experiments were conducted in a custom-designed behavioral arena to assess how blue light influences these parameters.

Ventilatory variables and computed tomography features in COVID-19 ARDS and non-COVID-19-related ARDS: a prospective observational cohort study.

Background: This study compared the ventilatory variables and computed tomography (CT) features of patients with coronavirus disease 2019 (COVID-19) versus those of patients with pulmonary non-COVID-19-related acute respiratory distress syndrome (ARDS) during the early phase of ARDS.

Methods: This prospective, observational cohort study of ARDS patients in Taiwan was performed between February 2017 and June 2018 as well as between October 2020 and January 2024. Analysis was performed on clinical characteristics, including consecutive ventilatory variables during the first week after ARDS diagnosis.

Interleukin-23 versus Interleukin-17 Inhibitors in Preventing Incidental Psoriatic Arthritis in Patients with Psoriasis: A Real-World Comparison From the TriNetX US Collaborative Network.

Background: Psoriatic arthritis (PsA) is a common comorbidity in patients with psoriasis (PsO) that leads to significant disease burden. Biologic therapies targeting the interleukin (IL)-23/IL-17 axis have been widely used for PsO, but their comparative effectiveness in preventing PsA remains unclear.

Objective: The study objective was to compare the occurrence of developing incidental PsA among PsO patients treated with interleukin-23 inhibitors (IL23is) or interleukin-17 inhibitors (IL17is).

Addressing healthcare disparities and improving osteoporosis management in rural communities: a cluster randomized control trial.

Unlabelled: Rural communities face healthcare challenges. This study assessed a multicomponent intervention to improve hospital visits and anti-osteoporosis medication (AOM) treatment rates. A total of 567 patients were randomized into three groups.

Dual modality feature fused neural network integrating binding site information for drug target affinity prediction.

Accurately predicting binding affinities between drugs and targets is crucial for drug discovery but remains challenging due to the complexity of modeling interactions between small drug and large targets. This study proposes DMFF-DTA, a dual-modality neural network model integrates sequence and graph structure information from drugs and proteins for drug-target affinity prediction. The model introduces a binding site-focused graph construction approach to extract binding information, enabling more balanced and efficient modeling of drug-target interactions.

Associations between common genetic variants and income provide insights about the socio-economic health gradient.

We conducted a genome-wide association study on income among individuals of European descent (N = 668,288) to investigate the relationship between socio-economic status and health disparities. We identified 162 genomic loci associated with a common genetic factor underlying various income measures, all with small effect sizes (the Income Factor). Our polygenic index captures 1-5% of income variance, with only one fourth due to direct genetic effects.

Soliton solutions of the (2 + 1)-dimensional Jaulent-Miodek evolution equation via effective analytical techniques.

In this study, we investigate the [Formula: see text]-D Jaulent-Miodek (JM) equation, which is significant due to its energy-based Schrödinger potential and applications in fields such as optics, soliton theory, signal processing, geophysics, fluid dynamics, and plasma physics. Given its broad utility, a rigorous mathematical analysis of the JM equation is essential. The primary objective of this work is to derive exact soliton solutions using the Modified Sub-Equation (MSE) and Modified Auxiliary Equation (MAE) techniques.